ZSWIM8-AS1

Summary

ZSWIM8-AS1 (ZSWIM8 antisense RNA 1, HGNC:45103) is a long non-coding RNA gene on chromosome 10q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45103
Approved symbol	ZSWIM8-AS1
Name	ZSWIM8 antisense RNA 1
Location	10q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272589
Ensembl biotype	lncRNA
Entrez	100507331
RNAcentral	URS000075C76D — lncRNA, 1476 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000456638

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456638 — 4 exons

Exon	Start	End
ENSE00001635134	73801340	73801399
ENSE00001733541	73796514	73797589
ENSE00001775921	73797822	73798088
ENSE00003706821	73800503	73800559

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 86.45.

Top tissues by expression

133 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.45	gold quality
cerebellar hemisphere	UBERON:0002245	83.84	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.76	gold quality
cerebellar cortex	UBERON:0002129	83.73	gold quality
cerebellum	UBERON:0002037	83.60	gold quality
right testis	UBERON:0004534	81.86	gold quality
muscle layer of sigmoid colon	UBERON:0035805	81.51	gold quality
left testis	UBERON:0004533	81.35	gold quality
right uterine tube	UBERON:0001302	81.09	gold quality
lower esophagus muscularis layer	UBERON:0035833	81.05	gold quality
lower esophagus	UBERON:0013473	81.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.73	gold quality
testis	UBERON:0000473	80.34	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	79.97	gold quality
spleen	UBERON:0002106	79.15	gold quality
mucosa of stomach	UBERON:0001199	78.99	gold quality
lower esophagus mucosa	UBERON:0035834	78.61	gold quality
granulocyte	CL:0000094	78.23	gold quality
left uterine tube	UBERON:0001303	77.32	gold quality
blood	UBERON:0000178	77.00	gold quality
esophagus	UBERON:0001043	76.60	gold quality
prostate gland	UBERON:0002367	76.47	gold quality
colon	UBERON:0001155	76.38	gold quality
small intestine Peyer’s patch	UBERON:0003454	76.38	gold quality
bone marrow	UBERON:0002371	76.18	gold quality
intestine	UBERON:0000160	75.53	gold quality
fundus of stomach	UBERON:0001160	75.41	gold quality
right lobe of thyroid gland	UBERON:0001119	75.29	gold quality
small intestine	UBERON:0002108	75.22	gold quality
transverse colon	UBERON:0001157	74.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.