{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:1097,10,HGNC:1097,33,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:1097","source":"HGNC:1097|B-Raf proto-oncogene, serine/threonine kinase","targets":["1013818|NM_004333.6(BRAF):c.1103A>G (p.Asn368Ser)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, single submitter|7","1018019|NM_004333.6(BRAF):c.84C>T (p.Gly28=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1018730|NM_004333.6(BRAF):c.41C>T (p.Pro14Leu)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1021694|NM_004333.6(BRAF):c.1331G>A (p.Arg444Gln)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1035210|NM_004333.6(BRAF):c.58A>G (p.Asn20Asp)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1038315|NM_004333.6(BRAF):c.969G>A (p.Ser323=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1046282|NM_004333.6(BRAF):c.1898A>G (p.Tyr633Cys)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, single submitter|7","1047782|NM_004333.6(BRAF):c.112G>C (p.Ala38Pro)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1050230|NM_004333.6(BRAF):c.1789C>T (p.Leu597=)|single nucleotide variant|Conflicting classifications of pathogenicity|BRAF|criteria provided, conflicting classifications|7","1050479|NM_004333.6(BRAF):c.1790T>C (p.Leu597Pro)|single nucleotide variant|Uncertain significance|BRAF|no assertion criteria provided|7","1054243|NM_004333.6(BRAF):c.2156G>A (p.Arg719His)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1058193|NM_004333.6(BRAF):c.929C>T (p.Thr310Ile)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1060771|NM_004333.6(BRAF):c.1662A>G (p.Ile554Met)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, single submitter|7","1064425|NM_004333.6(BRAF):c.1759G>A (p.Asp587Asn)|single nucleotide variant|Uncertain significance|BRAF|no assertion criteria provided|7","1065152|NM_004333.6(BRAF):c.858T>G (p.Leu286=)|single nucleotide variant|Conflicting classifications of pathogenicity|BRAF|criteria provided, conflicting classifications|7","1082791|NM_004333.6(BRAF):c.987A>G (p.Gln329=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1084088|NM_004333.6(BRAF):c.1767A>C (p.Thr589=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1086044|NM_004333.6(BRAF):c.1330C>A (p.Arg444=)|single nucleotide variant|Benign/Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1086109|NM_004333.6(BRAF):c.81C>T (p.Ala27=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1091347|NM_004333.6(BRAF):c.915G>A (p.Ala305=)|single nucleotide variant|Conflicting classifications of pathogenicity|BRAF|criteria provided, conflicting classifications|7","1094511|NM_004333.6(BRAF):c.957C>G (p.Ser319=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1096283|NM_004333.6(BRAF):c.1993-10C>A|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1098828|NM_004333.6(BRAF):c.612G>A (p.Glu204=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1115576|NM_004333.6(BRAF):c.1491C>T (p.Ala497=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1115802|NM_004333.6(BRAF):c.1203C>A (p.Thr401=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1130636|NM_004333.6(BRAF):c.1797A>G (p.Thr599=)|single nucleotide variant|Conflicting classifications of pathogenicity|BRAF|criteria provided, conflicting classifications|7","1131755|NM_004333.6(BRAF):c.1140+7A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1137370|NM_004333.6(BRAF):c.139-9del|Deletion|Likely benign|BRAF|criteria provided, single submitter|7","1147384|NM_004333.6(BRAF):c.1719C>A (p.Ile573=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1154928|NM_004333.6(BRAF):c.1848C>A (p.Ser616=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1157284|NM_004333.6(BRAF):c.87C>T (p.Ala29=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1163474|NM_004333.6(BRAF):c.1402T>C (p.Phe468Leu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","1163475|NM_004333.6(BRAF):c.786A>G (p.Gln262=)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, single submitter|7","1176544|NM_004333.6(BRAF):c.1070T>C (p.Phe357Ser)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1176545|NM_004333.6(BRAF):c.141G>A (p.Val47=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1181586|NM_004333.6(BRAF):c.156A>G (p.Gln52=)|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1181744|NM_004333.6(BRAF):c.1177+247del|Deletion|Likely benign|BRAF|criteria provided, single submitter|7","1182644|NM_004333.6(BRAF):c.2128-280T>C|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1182987|NM_004333.6(BRAF):c.2128-26T>C|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1185866|NM_004333.6(BRAF):c.1177+224_1177+225dup|Duplication|Likely benign|BRAF|criteria provided, single submitter|7","1188158|NM_004333.6(BRAF):c.901C>T (p.Pro301Ser)|single nucleotide variant|Conflicting classifications of pathogenicity|BRAF|criteria provided, conflicting classifications|7","1192217|NM_004333.6(BRAF):c.608+19G>A|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1192823|NM_004333.6(BRAF):c.504+76A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1192978|NM_004333.6(BRAF):c.1178-271T>C|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1193097|NM_004333.6(BRAF):c.138+226C>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1195613|NM_004333.6(BRAF):c.1518-117A>T|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1197861|NM_004333.6(BRAF):c.1177+158C>T|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1198003|NM_004333.6(BRAF):c.1448A>T (p.Lys483Ile)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","1198516|NC_000007.14:g.140924965G>A|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1198861|NM_004333.6(BRAF):c.609-294_609-290del|Deletion|Likely benign|BRAF|criteria provided, single submitter|7","1198981|NM_004333.6(BRAF):c.2128-15T>C|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1199855|NM_004333.6(BRAF):c.609-315_609-313dup|Duplication|Likely benign|BRAF|criteria provided, single submitter|7","1200852|NM_004333.6(BRAF):c.2128-210A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1201232|NM_004333.6(BRAF):c.2127+282dup|Duplication|Likely benign|BRAF|criteria provided, single submitter|7","1201760|NM_004333.6(BRAF):c.2127+206A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1202093|NM_004333.6(BRAF):c.609-315dup|Duplication|Likely benign|BRAF|criteria provided, single submitter|7","1203496|NM_004333.6(BRAF):c.1518-117dup|Duplication|Likely benign|BRAF|criteria provided, single submitter|7","1204045|NM_004333.6(BRAF):c.1518-282T>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1204135|NM_004333.6(BRAF):c.1742-29A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1205020|NM_004333.6(BRAF):c.241-149A>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1205197|NM_004333.6(BRAF):c.1993-11T>C|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1207147|NM_004333.6(BRAF):c.861-170A>T|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1207528|NM_004333.6(BRAF):c.1314+153G>C|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1210729|NM_004333.6(BRAF):c.2125C>G (p.Gln709Glu)|single nucleotide variant|Pathogenic|BRAF|criteria provided, single submitter|7","1211859|NM_004333.6(BRAF):c.505-292G>A|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1214656|NM_004333.6(BRAF):c.1315-338C>T|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1215321|NM_004333.6(BRAF):c.81C>G (p.Ala27=)|single nucleotide variant|Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1216776|NM_004333.6(BRAF):c.1433-162T>G|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1219184|NM_004333.6(BRAF):c.1860+156T>A|single nucleotide variant|Likely benign|BRAF|criteria provided, single submitter|7","1219871|NM_004333.6(BRAF):c.260G>A (p.Ser87Asn)|single nucleotide variant|Uncertain significance|BRAF|criteria provided, multiple submitters, no conflicts|7","1225064|NM_004333.6(BRAF):c.981-42C>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1226175|NM_004333.6(BRAF):c.2128-51_2128-50insTTTCT|Microsatellite|Benign|BRAF|criteria provided, single submitter|7","1227321|NM_004333.6(BRAF):c.980+52T>C|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1227662|NM_004333.6(BRAF):c.2128-50T>C|single nucleotide variant|Benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1227805|NM_004333.6(BRAF):c.1177+240_1177+247del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1237833|NM_004333.6(BRAF):c.609-292_609-290del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1239626|NM_004333.6(BRAF):c.609-293_609-290del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1243788|NM_004333.6(BRAF):c.1517+64A>G|single nucleotide variant|Benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1245513|NM_004333.6(BRAF):c.240+282ATTT[2]|Microsatellite|Benign|BRAF|criteria provided, single submitter|7","1245894|NM_004333.6(BRAF):c.2128-275A>G|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1252253|NM_004333.6(BRAF):c.1695-90T>A|single nucleotide variant|Benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1252895|NM_004333.6(BRAF):c.980+84A>G|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1253534|NM_004333.6(BRAF):c.1860+108A>G|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1262732|NM_004333.6(BRAF):c.1993-241A>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1264484|NM_004333.6(BRAF):c.1177+224dup|Duplication|Benign|BRAF|criteria provided, single submitter|7","1268111|NM_004333.6(BRAF):c.2127+283C>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1270239|NM_004333.6(BRAF):c.2127+291_2127+292del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1270731|NM_004333.6(BRAF):c.1141-110G>A|single nucleotide variant|Benign/Likely benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1273249|NM_004333.6(BRAF):c.609-289G>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1274282|NM_004333.6(BRAF):c.138+32G>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1276505|NM_004333.6(BRAF):c.241-30G>T|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1280023|NM_004333.6(BRAF):c.609-291_609-290del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1281713|NM_004333.6(BRAF):c.2127+292del|Deletion|Benign|BRAF|criteria provided, single submitter|7","1282076|NM_004333.6(BRAF):c.2128-62CTTT[4]|Microsatellite|Benign|BRAF|criteria provided, single submitter|7","1290137|NM_004333.6(BRAF):c.1140+45A>G|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1290404|NM_004333.6(BRAF):c.2128-34T>C|single nucleotide variant|Benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1292352|NM_004333.6(BRAF):c.861-54A>G|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1292353|NM_004333.6(BRAF):c.712-61G>A|single nucleotide variant|Benign|BRAF|criteria provided, multiple submitters, no conflicts|7","1292354|NM_004333.6(BRAF):c.-173G>A|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7","1292355|NM_004333.6(BRAF):c.1596T>C (p.Cys532=)|single nucleotide variant|Benign|BRAF|criteria provided, single submitter|7"]}]}