{"context":{"query":">>hgnc>>clinvar[germline_classification==\"Likely pathogenic\"]","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":38,"mapped":1},"pagination":{"has_next":false},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:1097","source":"HGNC:1097|B-Raf proto-oncogene, serine/threonine kinase","targets":["1163474|NM_004333.6(BRAF):c.1402T>C (p.Phe468Leu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","1198003|NM_004333.6(BRAF):c.1448A>T (p.Lys483Ile)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","1320917|NM_004333.6(BRAF):c.708C>G (p.Asn236Lys)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, multiple submitters, no conflicts|7","177776|NM_004333.6(BRAF):c.1742A>G (p.Asn581Ser)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","2769805|NM_004333.6(BRAF):c.1695T>A (p.Asp565Glu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, multiple submitters, no conflicts|7","279935|NM_004333.6(BRAF):c.1493T>A (p.Phe498Tyr)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","3220902|NM_004333.6(BRAF):c.1749T>G (p.Phe583Leu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","3338728|NM_004333.6(BRAF):c.1099C>G (p.Pro367Ala)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","3343956|NM_004333.6(BRAF):c.2132T>C (p.Leu711Pro)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","3393207|NM_004333.6(BRAF):c.794G>C (p.Gly265Ala)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","372757|NM_004333.6(BRAF):c.1765A>C (p.Thr589Pro)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","375944|NM_004333.6(BRAF):c.1782T>G (p.Asp594Glu)|single nucleotide variant|Likely pathogenic|BRAF|no assertion criteria provided|7","375948|NM_004333.6(BRAF):c.1779_1780delinsGA (p.Asp594Asn)|Indel|Likely pathogenic|BRAF|no assertion criteria provided|7","394939|GRCh37/hg19 7q34(chr7:140616125-140740863)x3|copy number gain|Likely pathogenic|BRAF|no assertion criteria provided|7","40349|NM_004333.6(BRAF):c.740T>C (p.Phe247Ser)|single nucleotide variant|Likely pathogenic|BRAF|reviewed by expert panel|7","40365|NM_004333.6(BRAF):c.1391G>C (p.Gly464Ala)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","40368|NM_004333.6(BRAF):c.1411G>A (p.Val471Ile)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","40370|NM_004333.6(BRAF):c.1454T>C (p.Leu485Ser)|single nucleotide variant|Likely pathogenic|BRAF|reviewed by expert panel|7","40379|NM_004333.6(BRAF):c.1592G>T (p.Trp531Leu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","40380|NM_004333.6(BRAF):c.1595G>A (p.Cys532Tyr)|single nucleotide variant|Likely pathogenic|BRAF|reviewed by expert panel|7","4072207|NM_004333.6(BRAF):c.1082A>T (p.Asp361Val)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","44804|NM_004333.6(BRAF):c.1409C>G (p.Thr470Arg)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, multiple submitters, no conflicts|7","44807|NM_004333.6(BRAF):c.1501G>C (p.Glu501Gln)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","44813|NM_004333.6(BRAF):c.1780G>A (p.Asp594Asn)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","44815|NM_004333.6(BRAF):c.1798G>A (p.Val600Met)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","44816|NM_004333.6(BRAF):c.1798G>T (p.Val600Leu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","44817|NM_004333.6(BRAF):c.1799_1801del (p.Val600_Lys601delinsGlu)|Deletion|Likely pathogenic|BRAF|criteria provided, single submitter|7","44830|NM_004333.6(BRAF):c.739T>G (p.Phe247Val)|single nucleotide variant|Likely pathogenic|BRAF|reviewed by expert panel|7","44832|NM_004333.6(BRAF):c.793G>C (p.Gly265Arg)|single nucleotide variant|Likely pathogenic|BRAF|reviewed by expert panel|7","575127|NM_004333.6(BRAF):c.1505_1507dup (p.Val502dup)|Duplication|Likely pathogenic|BRAF|criteria provided, single submitter|7","599445|NM_004333.6(BRAF):c.1388_1408dup (p.Ile463_Gly469dup)|Duplication|Likely pathogenic|BRAF|criteria provided, single submitter|7","636502|NM_004333.6(BRAF):c.1441_1442delinsAA (p.Ala481Lys)|Indel|Likely pathogenic|BRAF|criteria provided, single submitter|7","645347|NM_004333.6(BRAF):c.1096G>C (p.Ala366Pro)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","666410|NM_004333.6(BRAF):c.1406_1411del (p.Gly469_Thr470del)|Deletion|Likely pathogenic|BRAF|no assertion criteria provided|7","666411|NM_004333.6(BRAF):c.1408A>C (p.Thr470Pro)|single nucleotide variant|Likely pathogenic|BRAF|no assertion criteria provided|7","802372|NM_004333.6(BRAF):c.2276G>A (p.Gly759Glu)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","802377|NM_004333.6(BRAF):c.644C>T (p.Ser215Phe)|single nucleotide variant|Likely pathogenic|BRAF|criteria provided, single submitter|7","976167|NM_004333.6(BRAF):c.1475_1477del (p.Pro492del)|Deletion|Likely pathogenic|BRAF|criteria provided, single submitter|7"]}]}