{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:1101,10,HGNC:1101,170,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:1101","source":"HGNC:1101|BRCA2 DNA repair associated","targets":["1000184|NM_000059.4(BRCA2):c.5491A>C (p.Ile1831Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1000548|NM_000059.4(BRCA2):c.2916A>C (p.Lys972Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1000707|NM_000059.4(BRCA2):c.8315A>G (p.Glu2772Gly)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1000790|NM_000059.4(BRCA2):c.4990A>G (p.Ile1664Val)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1001380|NM_000059.4(BRCA2):c.9176A>G (p.Lys3059Arg)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1001460|NM_000059.4(BRCA2):c.3461C>A (p.Thr1154Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1001575|NM_000059.4(BRCA2):c.8008T>C (p.Ser2670Pro)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1001941|NM_000059.4(BRCA2):c.9022A>T (p.Ile3008Phe)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1002158|NM_000059.4(BRCA2):c.7918A>G (p.Lys2640Glu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1002261|NM_000059.4(BRCA2):c.10199G>C (p.Ser3400Thr)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1002381|NM_000059.4(BRCA2):c.4208C>T (p.Thr1403Ile)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1002452|NM_000059.4(BRCA2):c.3128C>T (p.Ala1043Val)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1002496|NM_000059.4(BRCA2):c.3344C>A (p.Ser1115Tyr)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1002504|NM_000059.4(BRCA2):c.8345G>C (p.Ser2782Thr)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1002572|NM_000059.4(BRCA2):c.560A>T (p.Glu187Val)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1002580|NM_000059.4(BRCA2):c.9718G>C (p.Val3240Leu)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1002811|NM_000059.4(BRCA2):c.-38C>T|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1002814|NM_000059.4(BRCA2):c.9457G>A (p.Gly3153Ser)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1003168|NM_000059.4(BRCA2):c.9056A>G (p.Lys3019Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1003281|NM_000059.4(BRCA2):c.7173A>C (p.Glu2391Asp)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1003304|NM_000059.4(BRCA2):c.7312G>A (p.Asp2438Asn)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1003413|NM_000059.4(BRCA2):c.6929C>T (p.Thr2310Ile)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1003450|NM_000059.4(BRCA2):c.10130A>G (p.Glu3377Gly)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1003710|NM_000059.4(BRCA2):c.6169G>A (p.Gly2057Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1003817|NM_000059.4(BRCA2):c.8910G>T (p.Trp2970Cys)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1003949|NM_000059.4(BRCA2):c.6366G>A (p.Met2122Ile)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1004040|NM_000059.4(BRCA2):c.3739A>G (p.Ile1247Val)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1004129|NM_000059.4(BRCA2):c.5728A>G (p.Asn1910Asp)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1004353|NM_000059.4(BRCA2):c.9476T>A (p.Phe3159Tyr)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1004457|NM_000059.4(BRCA2):c.8331+3A>G|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1005003|NM_000059.4(BRCA2):c.7892T>C (p.Leu2631Pro)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005106|NM_000059.4(BRCA2):c.3624A>C (p.Leu1208Phe)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005180|NM_000059.4(BRCA2):c.2008T>G (p.Cys670Gly)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005400|NM_000059.4(BRCA2):c.2759C>G (p.Pro920Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005600|NM_000059.4(BRCA2):c.5493A>G (p.Ile1831Met)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005825|NM_000059.4(BRCA2):c.6071A>T (p.Gln2024Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1005937|NM_000059.4(BRCA2):c.7219G>C (p.Val2407Leu)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1005995|NM_000059.4(BRCA2):c.7064A>G (p.Glu2355Gly)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1006123|NM_000059.4(BRCA2):c.1970T>G (p.Leu657Trp)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1006462|NM_000059.4(BRCA2):c.715A>G (p.Ser239Gly)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1006585|NM_000059.4(BRCA2):c.7414A>C (p.Lys2472Gln)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1006966|NM_000059.4(BRCA2):c.468T>G (p.Asp156Glu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1007322|NM_000059.4(BRCA2):c.644A>T (p.Glu215Val)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1007420|NM_000059.4(BRCA2):c.2996C>T (p.Pro999Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1007476|NM_000059.4(BRCA2):c.3708A>T (p.Lys1236Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1007501|NM_000059.4(BRCA2):c.8180C>T (p.Ala2727Val)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1007715|NM_000059.4(BRCA2):c.9653C>T (p.Ser3218Phe)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1007927|NM_000059.4(BRCA2):c.4436G>A (p.Ser1479Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1008104|NM_000059.4(BRCA2):c.7797A>C (p.Glu2599Asp)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1008199|NM_000059.4(BRCA2):c.9665G>A (p.Cys3222Tyr)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1008514|NM_000059.4(BRCA2):c.9668A>T (p.Glu3223Val)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1008583|NM_000059.4(BRCA2):c.8369C>G (p.Thr2790Ser)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1008584|NM_000059.4(BRCA2):c.4738T>C (p.Cys1580Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1008590|NM_000059.4(BRCA2):c.1817C>G (p.Pro606Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009212|NM_000059.4(BRCA2):c.9067G>T (p.Ala3023Ser)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1009220|NM_000059.4(BRCA2):c.1145A>G (p.Lys382Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009339|NM_000059.4(BRCA2):c.5886_5887delinsTA (p.Gly1963Arg)|Indel|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009410|NM_000059.4(BRCA2):c.3495T>G (p.His1165Gln)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009557|NM_000059.4(BRCA2):c.2973C>G (p.Asn991Lys)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009654|NM_000059.4(BRCA2):c.4054G>A (p.Asp1352Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1009962|NM_000059.4(BRCA2):c.9347C>G (p.Pro3116Arg)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1009999|NM_000059.4(BRCA2):c.8746T>C (p.Tyr2916His)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1010135|NM_000059.4(BRCA2):c.5942C>G (p.Ala1981Gly)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1010397|NM_000059.4(BRCA2):c.4287G>T (p.Gln1429His)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1010580|NM_000059.4(BRCA2):c.475+4T>A|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1010616|NM_000059.4(BRCA2):c.962A>C (p.Gln321Pro)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1010733|NM_000059.4(BRCA2):c.6575T>C (p.Met2192Thr)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1011057|NM_000059.4(BRCA2):c.7805+19T>G|single nucleotide variant|Likely benign|BRCA2|criteria provided, multiple submitters, no conflicts|13","1011290|NM_000059.4(BRCA2):c.3153G>C (p.Leu1051Phe)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1011297|NM_000059.4(BRCA2):c.2955A>T (p.Lys985Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1011473|NM_000059.4(BRCA2):c.10218A>C (p.Lys3406Asn)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1011729|NM_000059.4(BRCA2):c.3527T>C (p.Val1176Ala)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1012001|NM_000059.4(BRCA2):c.9383G>T (p.Arg3128Leu)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1012157|NM_000059.4(BRCA2):c.9163del (p.Leu3055fs)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012158|NM_000059.4(BRCA2):c.5934del (p.Phe1978fs)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012159|NM_000059.4(BRCA2):c.5566_5567inv (p.His1856Cys)|Inversion|Pathogenic|BRCA2|no assertion criteria provided|13","1012160|NM_000059.4(BRCA2):c.5362del (p.Ser1788fs)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012161|NM_000059.4(BRCA2):c.5297del (p.Asn1766fs)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012162|NM_000059.4(BRCA2):c.1561del (p.Ser521fs)|Deletion|Pathogenic|BRCA2|criteria provided, single submitter|13","1012163|NM_000059.4(BRCA2):c.1053del (p.Lys351fs)|Deletion|Pathogenic/Likely pathogenic|BRCA2|criteria provided, multiple submitters, no conflicts|13","1012164|NM_000059.4(BRCA2):c.728del (p.Asn243fs)|Deletion|Pathogenic|BRCA2|criteria provided, multiple submitters, no conflicts|13","1012165|NM_000059.4(BRCA2):c.691_692delinsGA (p.Ser231Asp)|Indel|Pathogenic|BRCA2|no assertion criteria provided|13","1012166|NM_000059.4(BRCA2):c.2588del (p.Asn863fs)|Deletion|Pathogenic|BRCA2|criteria provided, single submitter|13","1012167|NM_000059.4(BRCA2):c.7177del (p.Lys2392_Met2393insTer)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012168|NM_000059.4(BRCA2):c.10248del (p.Lys3416fs)|Deletion|Pathogenic|BRCA2|no assertion criteria provided|13","1012202|NM_000059.4(BRCA2):c.8423_8427delinsA (p.Leu2808fs)|Indel|Pathogenic|BRCA2|criteria provided, single submitter|13","1012203|NM_000059.4(BRCA2):c.8487+2T>G|single nucleotide variant|Pathogenic|BRCA2|criteria provided, single submitter|13","1012631|NM_000059.4(BRCA2):c.1490_1493del (p.Ser497fs)|Deletion|Pathogenic|BRCA2|criteria provided, single submitter|13","1014181|NM_000059.4(BRCA2):c.4213A>C (p.Asn1405His)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1014423|NC_000013.10:g.(?_32899193)_(32972907_?)dup|Duplication|Uncertain significance|BRCA2|criteria provided, single submitter|13","1014486|NM_000059.4(BRCA2):c.6258C>G (p.Ile2086Met)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1014504|NM_000059.4(BRCA2):c.5222_5224del (p.Ser1741del)|Deletion|Uncertain significance|BRCA2|criteria provided, multiple submitters, no conflicts|13","1014505|NM_000059.4(BRCA2):c.5502T>A (p.Ser1834Arg)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1014602|NM_000059.4(BRCA2):c.5558G>A (p.Cys1853Tyr)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1014828|NM_000059.4(BRCA2):c.4117A>T (p.Met1373Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1014837|NM_000059.4(BRCA2):c.2935A>G (p.Ile979Val)|single nucleotide variant|Conflicting classifications of pathogenicity|BRCA2|criteria provided, conflicting classifications|13","1015159|NM_000059.4(BRCA2):c.5581_5583del (p.Lys1861del)|Deletion|Uncertain significance|BRCA2|criteria provided, single submitter|13","1015347|NM_000059.4(BRCA2):c.7850G>A (p.Arg2617Lys)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1015352|NM_000059.4(BRCA2):c.8916G>T (p.Leu2972Phe)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13","1015355|NM_000059.4(BRCA2):c.7228T>C (p.Phe2410Leu)|single nucleotide variant|Uncertain significance|BRCA2|criteria provided, single submitter|13"]}]}