{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:11138,10,HGNC:11138,60,2]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:11138","source":"HGNC:11138|synuclein alpha","targets":["1003636|NM_000345.4(SNCA):c.100A>G (p.Lys34Glu)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1009952|NM_000345.4(SNCA):c.47T>C (p.Val16Ala)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1020728|NM_000345.4(SNCA):c.*464C>A|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1049281|NM_000345.4(SNCA):c.391G>C (p.Glu131Gln)|single nucleotide variant|Uncertain significance|SNCA|no assertion criteria provided|4","1051847|NM_000345.4(SNCA):c.71A>G (p.Gln24Arg)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1120010|GRCh37/hg19 4q22.1(chr4:90647764-90758128)|copy number gain|Pathogenic|SNCA|criteria provided, single submitter|4","1147109|NM_000345.4(SNCA):c.306+7C>T|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1196020|NM_000345.4(SNCA):c.390+36T>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1196419|NM_000345.4(SNCA):c.122-100A>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1199658|NM_000345.4(SNCA):c.163+206A>G|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1200375|NM_000345.4(SNCA):c.391-211ACT[4]|Microsatellite|Likely benign|SNCA|criteria provided, single submitter|4","1201597|NM_000345.4(SNCA):c.122-135_122-134insTATTT|Microsatellite|Likely benign|SNCA|criteria provided, single submitter|4","1211371|NM_000345.4(SNCA):c.121+165G>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1214888|NM_000345.4(SNCA):c.121+72G>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1222121|NM_000345.4(SNCA):c.121+277C>G|single nucleotide variant|Benign|SNCA|criteria provided, single submitter|4","1223289|NM_000345.4(SNCA):c.306+78dup|Duplication|Benign|SNCA|criteria provided, single submitter|4","1232535|NM_000345.4(SNCA):c.122-174_122-173del|Deletion|Benign|SNCA|criteria provided, single submitter|4","1243292|NM_000345.4(SNCA):c.163+162T>A|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1243971|NM_000345.4(SNCA):c.122-136A>T|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1252508|NM_000345.4(SNCA):c.391-54A>G|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1291645|NM_000345.4(SNCA):c.122-135_122-131dup|Duplication|Benign|SNCA|criteria provided, single submitter|4","1296756|NM_000345.4(SNCA):c.306+66G>A|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1296765|NM_000345.4(SNCA):c.164-316G>C|single nucleotide variant|Benign|SNCA|criteria provided, single submitter|4","1296792|NM_000345.4(SNCA):c.121+148G>C|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1301528|NM_000345.4(SNCA):c.370G>T (p.Ala124Ser)|single nucleotide variant|Uncertain significance|SNCA|no assertion criteria provided|4","1339894|GRCh37/hg19 4q22.1(chr4:90647779-90756863)x3|copy number gain|not provided|SNCA|no classification provided|4","1372807|NC_000004.11:g.(?_90647315)_(90756828_?)del|Deletion|Uncertain significance|SNCA|criteria provided, single submitter|4","1373474|NM_000345.4(SNCA):c.122-2A>C|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1388864|NM_000345.4(SNCA):c.163+6C>A|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1393530|NM_000345.4(SNCA):c.158C>T (p.Ala53Val)|single nucleotide variant|Conflicting classifications of pathogenicity|SNCA|criteria provided, conflicting classifications|4","14007|NM_000345.4(SNCA):c.157G>A (p.Ala53Thr)|single nucleotide variant|Pathogenic|SNCA|criteria provided, multiple submitters, no conflicts|4","14008|NM_000345.4(SNCA):c.88G>C (p.Ala30Pro)|single nucleotide variant|Likely pathogenic|SNCA|criteria provided, single submitter|4","14010|NM_000345.4(SNCA):c.136G>A (p.Glu46Lys)|single nucleotide variant|Pathogenic|SNCA|criteria provided, single submitter|4","1454898|NC_000004.11:g.(?_90647779)_(90756818_?)dup|Duplication|Pathogenic|SNCA|criteria provided, single submitter|4","1472092|NM_000345.4(SNCA):c.391-7A>G|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1509118|NM_000345.4(SNCA):c.247G>C (p.Glu83Gln)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1524438|NM_000345.4(SNCA):c.359C>T (p.Pro120Leu)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","1553611|NM_000345.4(SNCA):c.390+11A>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1590414|NM_000345.4(SNCA):c.306+8T>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","162095|NM_000345.4(SNCA):c.150T>G (p.His50Gln)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, multiple submitters, no conflicts|4","1654927|NM_000345.4(SNCA):c.121+13C>T|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1657000|NM_000345.4(SNCA):c.391-16A>G|single nucleotide variant|Likely benign|SNCA|criteria provided, multiple submitters, no conflicts|4","1670833|NM_000345.4(SNCA):c.246G>A (p.Val82=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1678622|NM_000345.4(SNCA):c.89C>G (p.Ala30Gly)|single nucleotide variant|Conflicting classifications of pathogenicity|SNCA|criteria provided, conflicting classifications|4","1698083|NM_000345.4(SNCA):c.164-108T>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1711594|NM_000345.4(SNCA):c.183G>A (p.Glu61=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1804058|NM_000345.4(SNCA):c.174G>C (p.Lys58Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|SNCA|criteria provided, conflicting classifications|4","1902821|NM_000345.4(SNCA):c.307-13C>T|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","1970513|NM_000345.4(SNCA):c.203G>A (p.Gly68Glu)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2038359|NM_000345.4(SNCA):c.349C>T (p.Pro117Ser)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2045977|NM_000345.4(SNCA):c.367G>A (p.Glu123Lys)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2163003|NM_000345.4(SNCA):c.217G>A (p.Gly73Ser)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2196956|NM_000345.4(SNCA):c.342A>C (p.Glu114Asp)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2475984|NM_000345.4(SNCA):c.187G>C (p.Val63Leu)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2573879|NM_000345.4(SNCA):c.106G>C (p.Gly36Arg)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2574845|NM_000345.4(SNCA):c.8T>A (p.Val3Glu)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2578966|NM_000345.4(SNCA):c.307-30022del|Deletion|Benign|SNCA|criteria provided, single submitter|4","2654945|NM_000345.4(SNCA):c.*1260CT[10]|Microsatellite|Benign|SNCA|criteria provided, single submitter|4","2654946|NM_000345.4(SNCA):c.102A>G (p.Lys34=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2654947|NM_000345.4(SNCA):c.9A>G (p.Val3=)|single nucleotide variant|Likely benign|SNCA|criteria provided, multiple submitters, no conflicts|4","2663805|NM_000345.4(SNCA):c.391-14T>C|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2923907|NM_000345.4(SNCA):c.381G>A (p.Met127Ile)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2924961|NM_000345.4(SNCA):c.31G>T (p.Ala11Ser)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2925064|NM_000345.4(SNCA):c.99A>G (p.Thr33=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2933325|NM_000345.4(SNCA):c.164-16T>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2934109|NM_000345.4(SNCA):c.121+9A>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2940508|NM_000345.4(SNCA):c.401A>G (p.Gln134Arg)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","2942456|NM_000345.4(SNCA):c.396G>T (p.Gly132=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2947523|NM_000345.4(SNCA):c.390+7G>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2947524|NM_000345.4(SNCA):c.375T>C (p.Tyr125=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2949370|NM_000345.4(SNCA):c.306+20G>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","2950001|NM_000345.4(SNCA):c.105G>A (p.Glu35=)|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","3068157|NM_000345.4(SNCA):c.106G>A (p.Gly36Ser)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","3365939|NM_000345.4(SNCA):c.280T>G (p.Phe94Val)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","3446670|NM_000345.4(SNCA):c.394G>A (p.Gly132Arg)|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350057|NM_000345.4(SNCA):c.*2501C>A|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350058|NM_000345.4(SNCA):c.*2330C>T|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350059|NM_000345.4(SNCA):c.*2291C>T|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","350060|NM_000345.4(SNCA):c.*2277A>C|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","350061|NM_000345.4(SNCA):c.*2269C>T|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350062|NM_000345.4(SNCA):c.*2227C>A|single nucleotide variant|Likely benign|SNCA|criteria provided, single submitter|4","350063|NM_000345.4(SNCA):c.*2108A>T|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","350064|NM_000345.4(SNCA):c.*2105G>A|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","350065|NM_000345.4(SNCA):c.*2037T>C|single nucleotide variant|Uncertain significance|SNCA|criteria provided, multiple submitters, no conflicts|4","350066|NM_000345.4(SNCA):c.*1896C>T|single nucleotide variant|Benign|SNCA|criteria provided, multiple submitters, no conflicts|4","350067|NM_000345.4(SNCA):c.*1702G>A|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350068|NM_000345.4(SNCA):c.*1677C>T|single nucleotide variant|Benign|SNCA|criteria provided, single submitter|4","350069|NM_000345.4(SNCA):c.*1325A>G|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350070|NM_000345.4(SNCA):c.*1307_*1311dup|Duplication|Uncertain significance|SNCA|criteria provided, single submitter|4","350071|NM_000345.4(SNCA):c.*1311del|Deletion|Uncertain significance|SNCA|criteria provided, single submitter|4","350072|NM_000345.4(SNCA):c.*1310_*1311insTTT|Insertion|Uncertain significance|SNCA|criteria provided, single submitter|4","350073|NM_000345.4(SNCA):c.*1310_*1311insTTTTT|Insertion|Uncertain significance|SNCA|criteria provided, single submitter|4","350074|NM_000345.4(SNCA):c.*1308_*1310dup|Duplication|Uncertain significance|SNCA|criteria provided, single submitter|4","350075|NM_000345.4(SNCA):c.*1306_*1310dup|Duplication|Uncertain significance|SNCA|criteria provided, single submitter|4","350076|NM_000345.4(SNCA):c.*1310A>T|single nucleotide variant|Uncertain significance|SNCA|criteria provided, single submitter|4","350077|NM_000345.4(SNCA):c.*1306_*1309dup|Duplication|Uncertain significance|SNCA|criteria provided, multiple submitters, no conflicts|4","350078|NM_000345.4(SNCA):c.*1305_*1309dup|Duplication|Uncertain significance|SNCA|criteria provided, multiple submitters, no conflicts|4","350079|NM_000345.4(SNCA):c.*1308_*1309dup|Duplication|Uncertain significance|SNCA|criteria provided, single submitter|4","350080|NM_000345.4(SNCA):c.*1291_*1292insTTT|Insertion|Uncertain significance|SNCA|criteria provided, single submitter|4","350081|NM_000345.4(SNCA):c.*1291_*1292insTTTTT|Insertion|Uncertain significance|SNCA|criteria provided, single submitter|4"]}]}