{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":27,"mapped":1},"pagination":{"has_next":false},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:1504","source":"HGNC:1504|caspase 3","targets":["1255108|NM_004346.4(CASP3):c.*337T>C|single nucleotide variant|Benign|CASP3|criteria provided, multiple submitters, no conflicts|4","2221338|NM_004346.4(CASP3):c.142A>G (p.Ile48Val)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","2323338|NM_004346.4(CASP3):c.764C>T (p.Thr255Ile)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","2474590|NM_004346.4(CASP3):c.377T>C (p.Ile126Thr)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","2535319|NM_004346.4(CASP3):c.73G>A (p.Glu25Lys)|single nucleotide variant|Likely benign|CASP3|criteria provided, single submitter|4","2542222|NM_004346.4(CASP3):c.697A>G (p.Met233Val)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","2556682|NM_004346.4(CASP3):c.670A>G (p.Lys224Glu)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","2685135|GRCh37/hg19 4q35.1(chr4:185521937-185609790)x1|copy number loss|Uncertain significance|CASP3|criteria provided, single submitter|4","3137596|NM_004346.4(CASP3):c.237A>T (p.Arg79Ser)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","3137597|NM_004346.4(CASP3):c.760G>A (p.Ala254Thr)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","3263427|NM_004346.4(CASP3):c.22G>A (p.Val8Met)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","3827549|NM_004346.4(CASP3):c.687G>C (p.Lys229Asn)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","3827550|NM_004346.4(CASP3):c.292G>C (p.Glu98Gln)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","4219380|NM_004346.4(CASP3):c.740T>A (p.Phe247Tyr)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","4219381|NM_004346.4(CASP3):c.490C>T (p.Arg164Cys)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","4304329|NM_004346.4(CASP3):c.605-124A>T|single nucleotide variant||CASP3||4","4304330|NM_004346.4(CASP3):c.308-71A>T|single nucleotide variant||CASP3||4","4304331|NM_004346.4(CASP3):c.179-1G>T|single nucleotide variant||CASP3||4","4304332|NM_004346.4(CASP3):c.179-27A>G|single nucleotide variant||CASP3||4","4304333|NM_004346.4(CASP3):c.-182-16C>A|single nucleotide variant||CASP3||4","4648463|NM_004346.4(CASP3):c.826T>C (p.Tyr276His)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","4648464|NM_004346.4(CASP3):c.674A>G (p.Gln225Arg)|single nucleotide variant|Uncertain significance|CASP3|criteria provided, single submitter|4","562989|GRCh37/hg19 4q32.1-35.2(chr4:159492464-190957473)x3|copy number gain|Pathogenic|CASP3|no assertion criteria provided|4","723418|NM_004346.4(CASP3):c.302G>A (p.Arg101His)|single nucleotide variant|Likely benign|CASP3|criteria provided, single submitter|4","751793|NM_004346.4(CASP3):c.498A>C (p.Thr166=)|single nucleotide variant|Likely benign|CASP3|criteria provided, single submitter|4","799089|NM_004346.4(CASP3):c.690T>G (p.Leu230=)|single nucleotide variant|Likely benign|CASP3|criteria provided, single submitter|4","872273|NM_004346.4(CASP3):c.526_528del (p.Ser176del)|Deletion|Uncertain significance|CASP3|criteria provided, single submitter|4"]}]}