{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:15979,10,HGNC:15979,131,2]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:15979","source":"HGNC:15979|tumor protein p63","targets":["1018494|NM_003722.5(TP63):c.796C>T (p.Arg266Ter)|single nucleotide variant|Pathogenic|TP63|criteria provided, single submitter|3","1024583|NM_003722.5(TP63):c.1861del (p.Ser621fs)|Deletion|Pathogenic|TP63|criteria provided, single submitter|3","1038841|NM_003722.5(TP63):c.1121C>T (p.Thr374Met)|single nucleotide variant|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1042494|NM_003722.5(TP63):c.1697C>T (p.Thr566Met)|single nucleotide variant|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1049484|NM_003722.5(TP63):c.580-11A>T|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1051579|NM_003722.5(TP63):c.1027C>G (p.Arg343Gly)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1054108|NM_003722.5(TP63):c.799G>A (p.Val267Ile)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1062831|NM_003722.5(TP63):c.1050A>T (p.Arg350Ser)|single nucleotide variant|Pathogenic|TP63|criteria provided, single submitter|3","1070564|NM_003722.5(TP63):c.1007G>A (p.Gly336Asp)|single nucleotide variant|Pathogenic/Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","1076262|NM_003722.5(TP63):c.1670G>T (p.Gly557Val)|single nucleotide variant|Pathogenic/Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","1104553|NM_003722.5(TP63):c.1885G>A (p.Gly629Ser)|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1110153|NM_003722.5(TP63):c.1626G>A (p.Pro542=)|single nucleotide variant|Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1138613|NM_003722.5(TP63):c.1213-17del|Deletion|Likely benign|TP63|criteria provided, single submitter|3","1151667|NM_003722.5(TP63):c.708C>T (p.His236=)|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1164337|NM_003722.5(TP63):c.62+6895T>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1167533|NM_003722.5(TP63):c.62+8236T>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1177730|NM_003722.5(TP63):c.62+50063C>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1177797|NM_003722.5(TP63):c.325-18252dup|Duplication|Likely benign|TP63|criteria provided, single submitter|3","1177997|NM_003722.5(TP63):c.767-333C>T|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1178002|NM_003722.5(TP63):c.1129+296dup|Duplication|Benign|TP63|criteria provided, single submitter|3","1178305|NM_003722.5(TP63):c.579+158T>A|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1178338|NM_003722.5(TP63):c.3G>T (p.Met1Ile)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1182249|NC_000003.12:g.189897324C>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1183005|NM_003722.5(TP63):c.767-93T>C|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1187502|NM_003722.5(TP63):c.1350-62A>G|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1188518|NM_003722.5(TP63):c.191+275A>C|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1189866|NM_003722.5(TP63):c.1350-56A>C|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1189873|NM_003722.5(TP63):c.766+105G>A|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1190738|NM_003722.5(TP63):c.566C>T (p.Ser189Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|TP63|criteria provided, conflicting classifications|3","1191899|NM_003722.5(TP63):c.1507+300T>C|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1193256|NM_003722.5(TP63):c.325-268A>G|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1193285|NM_003722.5(TP63):c.766+104C>T|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1193434|NM_003722.5(TP63):c.882+321T>G|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1199099|NM_003722.5(TP63):c.1508-126C>T|single nucleotide variant|Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1202029|NM_003722.5(TP63):c.325-18195A>G|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1202722|NM_003722.5(TP63):c.374A>C (p.Gln125Pro)|single nucleotide variant|Conflicting classifications of pathogenicity|TP63|criteria provided, conflicting classifications|3","1204553|NM_003722.5(TP63):c.62+225C>T|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1206637|NM_003722.5(TP63):c.1129+202A>C|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1211813|NM_003722.5(TP63):c.1508-29C>A|single nucleotide variant|Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1214233|NM_003722.5(TP63):c.192-287A>G|single nucleotide variant|Likely benign|TP63|criteria provided, single submitter|3","1214793|NM_003722.5(TP63):c.1350-6145G>A|single nucleotide variant|Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1215430|NM_003722.5(TP63):c.883-88G>C|single nucleotide variant|Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1223026|NM_003722.5(TP63):c.1507+269A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1224575|NM_003722.5(TP63):c.63-6274G>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1225374|NM_003722.5(TP63):c.62+49875T>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1228444|NM_003722.5(TP63):c.62+25276G>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1229143|NM_003722.5(TP63):c.1349+40G>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1232095|NM_003722.5(TP63):c.1212+79A>G|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1233682|NM_003722.5(TP63):c.1507+264C>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1233871|NM_003722.5(TP63):c.62+50004G>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1234137|NM_003722.5(TP63):c.62+24991T>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1234146|NM_003722.5(TP63):c.62+50167A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1236039|NM_003722.5(TP63):c.191+254C>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1236231|NM_003722.5(TP63):c.992+121C>T|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1238951|NM_003722.5(TP63):c.1129+125C>G|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1241847|NM_003722.5(TP63):c.62+24867G>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1243129|NM_003722.5(TP63):c.1130-237T>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1244344|NM_003722.5(TP63):c.1349+269G>T|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1251400|NM_003722.5(TP63):c.993-187A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1254122|NM_003722.5(TP63):c.63-6388del|Deletion|Benign|TP63|criteria provided, single submitter|3","1256918|NM_003722.5(TP63):c.63-30964A>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1264717|NM_003722.5(TP63):c.992+299T>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1264861|NM_003722.5(TP63):c.62+49783A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1266631|NM_003722.5(TP63):c.1130-283A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1267398|NM_003722.5(TP63):c.63-6066G>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1268379|NM_003722.5(TP63):c.324+166C>G|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1270627|NM_003722.5(TP63):c.63-336A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1271522|NM_003722.5(TP63):c.63-149A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1272622|NM_003722.5(TP63):c.766+294A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1276115|NM_003722.5(TP63):c.63-6311C>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1279583|NM_003722.5(TP63):c.579+39T>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1281945|NM_003722.5(TP63):c.1653-264C>T|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1285650|NM_003722.5(TP63):c.324+76T>C|single nucleotide variant|Benign|TP63|criteria provided, multiple submitters, no conflicts|3","1290389|NM_003722.5(TP63):c.1350-34T>C|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1290390|NM_003722.5(TP63):c.882+304G>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1290392|NM_003722.5(TP63):c.325-75_325-74del|Deletion|Benign|TP63|criteria provided, single submitter|3","1290454|NM_003722.5(TP63):c.767-40A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1294557|NM_003722.5(TP63):c.1127G>A (p.Arg376His)|single nucleotide variant|Benign/Likely benign|TP63|criteria provided, multiple submitters, no conflicts|3","1296334|NM_003722.5(TP63):c.767-338A>G|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1298948|NM_003722.5(TP63):c.1350-6232G>A|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1299512|NM_003722.5(TP63):c.881A>G (p.Gln294Arg)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1310383|NM_003722.5(TP63):c.1204T>C (p.Tyr402His)|single nucleotide variant|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1314992|NM_003722.5(TP63):c.2021G>A (p.Arg674His)|single nucleotide variant|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1319322|NM_003722.5(TP63):c.1350-5670A>G|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1325219|NM_003722.5(TP63):c.970_972del (p.Ile324del)|Deletion|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","1327237|NM_003722.5(TP63):c.62+49918G>A|single nucleotide variant|Benign|TP63|criteria provided, single submitter|3","1328849|NM_003722.5(TP63):c.383C>T (p.Ser128Phe)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1333323|NM_003722.5(TP63):c.802G>A (p.Glu268Lys)|single nucleotide variant|Conflicting classifications of pathogenicity|TP63|criteria provided, conflicting classifications|3","1333911|NM_003722.5(TP63):c.858dup (p.Leu287fs)|Duplication|Likely pathogenic|TP63|criteria provided, single submitter|3","1335553|NM_001114980.2(TP63):c.2T>C (p.Met1Thr)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1341520|NM_003722.5(TP63):c.1789A>T (p.Ile597Phe)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1344645|NM_003722.5(TP63):c.1012C>T (p.Arg338Cys)|single nucleotide variant|Likely pathogenic|TP63|no assertion criteria provided|3","1346037|NM_003722.5(TP63):c.1497G>A (p.Met499Ile)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1349518|NM_003722.5(TP63):c.1973G>A (p.Trp658Ter)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1358479|NM_003722.5(TP63):c.1550A>G (p.Asn517Ser)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1370075|NM_003722.5(TP63):c.1320G>T (p.Gln440His)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3","1370657|NM_003722.5(TP63):c.1831TCC[1] (p.Ser612del)|Microsatellite|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1370798|NM_003722.5(TP63):c.1537G>C (p.Ala513Pro)|single nucleotide variant|Conflicting classifications of pathogenicity|TP63|criteria provided, conflicting classifications|3","1375700|NM_003722.5(TP63):c.1507+6_1507+7del|Microsatellite|Uncertain significance|TP63|criteria provided, multiple submitters, no conflicts|3","1380856|NM_003722.5(TP63):c.411C>G (p.Asp137Glu)|single nucleotide variant|Uncertain significance|TP63|criteria provided, single submitter|3"]}]}