{"context":{"query":">>hgnc>>clinvar[germline_classification==\"Likely pathogenic\"]","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":50,"mapped":1},"pagination":{"has_next":false},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:15979","source":"HGNC:15979|tumor protein p63","targets":["1178338|NM_003722.5(TP63):c.3G>T (p.Met1Ile)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1299512|NM_003722.5(TP63):c.881A>G (p.Gln294Arg)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1325219|NM_003722.5(TP63):c.970_972del (p.Ile324del)|Deletion|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","1333911|NM_003722.5(TP63):c.858dup (p.Leu287fs)|Duplication|Likely pathogenic|TP63|criteria provided, single submitter|3","1341520|NM_003722.5(TP63):c.1789A>T (p.Ile597Phe)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1344645|NM_003722.5(TP63):c.1012C>T (p.Arg338Cys)|single nucleotide variant|Likely pathogenic|TP63|no assertion criteria provided|3","1349518|NM_003722.5(TP63):c.1973G>A (p.Trp658Ter)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1475057|NM_003722.5(TP63):c.1695C>G (p.Phe565Leu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1481716|NM_003722.5(TP63):c.517G>A (p.Gly173Ser)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1486558|NM_003722.5(TP63):c.797G>T (p.Arg266Leu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1492561|NM_003722.5(TP63):c.1769C>T (p.Pro590Leu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","1493391|NM_003722.5(TP63):c.929G>A (p.Ser310Asn)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","1675940|NM_003722.5(TP63):c.1717_1719dup (p.Ile573dup)|Duplication|Likely pathogenic|TP63|criteria provided, single submitter|3","1684042|NM_003722.5(TP63):c.563_571del (p.Lys188_Ala190del)|Deletion|Likely pathogenic|TP63|criteria provided, single submitter|3","1711583|NM_003722.5(TP63):c.934T>G (p.Cys312Gly)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2019212|NM_003722.5(TP63):c.731G>T (p.Cys244Phe)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2025488|NM_003722.5(TP63):c.956G>C (p.Arg319Pro)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2087371|NM_003722.5(TP63):c.1768C>T (p.Pro590Ser)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2203760|NM_003722.5(TP63):c.925A>G (p.Asn309Asp)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2434205|NM_003722.5(TP63):c.1963C>T (p.Arg655Ter)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","2502308|NM_003722.5(TP63):c.899C>T (p.Thr300Met)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2579131|NM_003722.5(TP63):c.604T>C (p.Tyr202His)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2630702|NM_003722.5(TP63):c.739C>G (p.His247Asp)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2636258|NM_003722.5(TP63):c.944G>A (p.Gly315Glu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2683855|NM_003722.5(TP63):c.589G>C (p.Glu197Gln)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","2686013|NM_003722.5(TP63):c.1283C>T (p.Pro428Leu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","30348|NM_003722.5(TP63):c.797G>C (p.Arg266Pro)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3233406|NM_003722.5(TP63):c.2032G>C (p.Glu678Gln)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3253399|NM_003722.5(TP63):c.1042C>T (p.Pro348Ser)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3377066|NM_003722.5(TP63):c.1646T>A (p.Ile549Asn)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3589070|NM_003722.5(TP63):c.345dup (p.Leu116fs)|Duplication|Likely pathogenic|TP63|criteria provided, single submitter|3","3589074|NM_003722.5(TP63):c.1129+1G>A|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3602938|NM_003722.5(TP63):c.796C>G (p.Arg266Gly)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3655584|NM_003722.5(TP63):c.1028G>T (p.Arg343Leu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","372786|NM_003722.5(TP63):c.605A>G (p.Tyr202Cys)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","372787|NM_003722.5(TP63):c.1048A>G (p.Arg350Gly)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","373009|NM_003722.5(TP63):c.942_944del (p.Gly315del)|Deletion|Likely pathogenic|TP63|criteria provided, single submitter|3","373405|NM_003722.5(TP63):c.1682G>A (p.Cys561Tyr)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3","381688|NM_003722.5(TP63):c.1805T>C (p.Leu602Pro)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","3910456|NM_003722.5(TP63):c.656del (p.Pro219fs)|Deletion|Likely pathogenic|TP63|criteria provided, single submitter|3","4073586|NM_003722.5(TP63):c.1862del (p.Ser621fs)|Deletion|Likely pathogenic|TP63|criteria provided, single submitter|3","418521|NM_003722.5(TP63):c.1922C>T (p.Ala641Val)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","493381|NM_003722.5(TP63):c.853_854del (p.Ser285fs)|Microsatellite|Likely pathogenic|TP63|criteria provided, single submitter|3","521882|NM_003722.5(TP63):c.500C>T (p.Ser167Phe)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","572273|NM_003722.5(TP63):c.497C>A (p.Pro166His)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","620399|NM_003722.5(TP63):c.1927C>T (p.Arg643Ter)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","651785|NM_003722.5(TP63):c.935G>T (p.Cys312Phe)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","653417|NM_003722.5(TP63):c.738C>G (p.Asn246Lys)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","6536|NM_003722.5(TP63):c.1681T>G (p.Cys561Gly)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, single submitter|3","846332|NM_003722.5(TP63):c.1061C>A (p.Ala354Glu)|single nucleotide variant|Likely pathogenic|TP63|criteria provided, multiple submitters, no conflicts|3"]}]}