{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:1773,10,HGNC:1773,2,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:1773","source":"HGNC:1773|cyclin dependent kinase 4","targets":["1000634|NM_000075.4(CDK4):c.784C>T (p.Pro262Ser)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1001651|NM_000075.4(CDK4):c.681T>G (p.Phe227Leu)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1006266|NM_000075.4(CDK4):c.632+6G>A|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1006343|NM_000075.4(CDK4):c.244C>G (p.Arg82Gly)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1006345|NM_000075.4(CDK4):c.841C>A (p.His281Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1006586|NM_000075.4(CDK4):c.354+6T>A|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1006626|NM_000075.4(CDK4):c.218+3G>A|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1006709|NM_000075.4(CDK4):c.734C>T (p.Pro245Leu)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1014049|NM_000075.4(CDK4):c.749C>A (p.Pro250His)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1014782|NM_000075.4(CDK4):c.494A>G (p.Tyr165Cys)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1017299|NM_000075.4(CDK4):c.644G>C (p.Cys215Ser)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1018679|NM_000075.4(CDK4):c.295G>A (p.Asp99Asn)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1018837|NM_000075.4(CDK4):c.291C>A (p.Asp97Glu)|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1019503|NM_000075.4(CDK4):c.652T>A (p.Ser218Thr)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1019806|NM_000075.4(CDK4):c.116T>C (p.Val39Ala)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1019892|NM_000075.4(CDK4):c.172G>A (p.Ala58Thr)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1020131|NM_000075.4(CDK4):c.392T>G (p.Leu131Arg)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1026483|NM_000075.4(CDK4):c.317A>G (p.Lys106Arg)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1035270|NM_000075.4(CDK4):c.753dup (p.Arg252fs)|Duplication|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1037596|NM_000075.4(CDK4):c.792G>A (p.Met264Ile)|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1039892|NM_000075.4(CDK4):c.629G>T (p.Arg210Leu)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1040537|NM_000075.4(CDK4):c.218+6_218+7delinsGT|Indel|Uncertain significance|CDK4|criteria provided, single submitter|12","1041436|NM_000075.4(CDK4):c.790A>G (p.Met264Val)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1042239|NM_000075.4(CDK4):c.907G>A (p.Glu303Lys)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1042979|NM_000075.4(CDK4):c.319G>A (p.Ala107Thr)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1044287|NM_000075.4(CDK4):c.646G>A (p.Gly216Arg)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1044516|NC_000012.11:g.(?_58140510)_(58145500_?)dup|Duplication|Uncertain significance|CDK4|criteria provided, single submitter|12","1046694|NM_000075.4(CDK4):c.872A>C (p.Gln291Pro)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1047410|NM_000075.4(CDK4):c.356A>C (p.Asp119Ala)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1047485|NM_000075.4(CDK4):c.571T>A (p.Tyr191Asn)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1051111|NM_000075.4(CDK4):c.736C>G (p.Arg246Gly)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1051733|NM_000075.4(CDK4):c.235G>C (p.Ala79Pro)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1052125|NM_000075.4(CDK4):c.782T>C (p.Val261Ala)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1054508|NM_000075.4(CDK4):c.848G>C (p.Arg283Pro)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1056495|NM_000075.4(CDK4):c.752C>T (p.Pro251Leu)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1057985|NM_000075.4(CDK4):c.38G>A (p.Gly13Asp)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1059743|NM_000075.4(CDK4):c.890del (p.Lys297fs)|Deletion|Uncertain significance|CDK4|criteria provided, single submitter|12","1059884|NM_000075.4(CDK4):c.200A>T (p.Glu67Val)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, single submitter|12","1061882|NM_000075.4(CDK4):c.700C>G (p.Pro234Ala)|single nucleotide variant|Uncertain significance|CDK4|criteria provided, multiple submitters, no conflicts|12","1077907|NM_000075.4(CDK4):c.630A>C (p.Arg210=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1079516|NM_000075.4(CDK4):c.372T>C (p.Phe124=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1079999|NM_000075.4(CDK4):c.355-4C>T|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1080541|NM_000075.4(CDK4):c.684-5del|Deletion|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1084916|NM_000075.4(CDK4):c.523-7C>T|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1086511|NM_000075.4(CDK4):c.804A>C (p.Gly268=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1086955|NM_000075.4(CDK4):c.801G>C (p.Ser267=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1089164|NM_000075.4(CDK4):c.864A>T (p.Arg288=)|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1089676|NM_000075.4(CDK4):c.633-6C>T|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1091234|NM_000075.4(CDK4):c.906G>C (p.Pro302=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1091522|NM_000075.4(CDK4):c.657A>G (p.Glu219=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1093173|NM_000075.4(CDK4):c.465G>A (p.Lys155=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1094979|NM_000075.4(CDK4):c.666G>A (p.Gln222=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1095351|NM_000075.4(CDK4):c.870G>T (p.Leu290=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1101660|NM_000075.4(CDK4):c.111G>A (p.Val37=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1103857|NM_000075.4(CDK4):c.708T>C (p.Asp236=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1104135|NM_000075.4(CDK4):c.216C>A (p.Val72=)|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1104870|NM_000075.4(CDK4):c.632+8A>G|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1107811|NM_000075.4(CDK4):c.588C>T (p.Asp196=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1108398|NM_000075.4(CDK4):c.399C>T (p.Ala133=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1109876|NM_000075.4(CDK4):c.444G>A (p.Val148=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1113929|NM_000075.4(CDK4):c.820-5C>T|single nucleotide variant|Conflicting classifications of pathogenicity|CDK4|criteria provided, conflicting classifications|12","1115162|NM_000075.4(CDK4):c.271C>T (p.Leu91=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1117640|NM_000075.4(CDK4):c.600T>G (p.Val200=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1118017|NM_000075.4(CDK4):c.663C>T (p.Asp221=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1118246|NM_000075.4(CDK4):c.339A>T (p.Pro113=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1118259|NM_000075.4(CDK4):c.276G>A (p.Val92=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1118809|NM_000075.4(CDK4):c.654T>C (p.Ser218=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1120990|NM_000075.4(CDK4):c.312G>A (p.Leu104=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1121591|NM_000075.4(CDK4):c.630A>G (p.Arg210=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1122011|NM_000075.4(CDK4):c.632+7G>A|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1122337|NM_000075.4(CDK4):c.667T>C (p.Leu223=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1126143|NM_000075.4(CDK4):c.219-5del|Deletion|Likely benign|CDK4|criteria provided, single submitter|12","1127442|NM_000075.4(CDK4):c.744C>T (p.Ala248=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1130534|NM_000075.4(CDK4):c.552A>G (p.Glu184=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1133306|NM_000075.4(CDK4):c.138A>G (p.Gly46=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1136120|NM_000075.4(CDK4):c.549C>G (p.Pro183=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1142500|NM_000075.4(CDK4):c.375A>G (p.Leu125=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1143350|NM_000075.4(CDK4):c.603C>G (p.Gly201=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1144228|NM_000075.4(CDK4):c.720A>G (p.Arg240=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1145091|NM_000075.4(CDK4):c.683+8del|Deletion|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1145829|NM_000075.4(CDK4):c.777G>C (p.Ser259=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1145875|NM_000075.4(CDK4):c.639C>T (p.Leu213=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1147811|NM_000075.4(CDK4):c.840A>G (p.Pro280=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1149311|NM_000075.4(CDK4):c.117C>A (p.Val39=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1152094|NM_000075.4(CDK4):c.683+10C>A|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1152275|NM_000075.4(CDK4):c.820-8C>A|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1152499|NM_000075.4(CDK4):c.87C>T (p.Gly29=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1153325|NM_000075.4(CDK4):c.120C>T (p.Pro40=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1155116|NM_000075.4(CDK4):c.102C>G (p.Leu34=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1155424|NM_000075.4(CDK4):c.219-9T>C|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1155671|NM_000075.4(CDK4):c.27G>A (p.Val9=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1157324|NM_000075.4(CDK4):c.105G>A (p.Lys35=)|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1158088|NM_000075.4(CDK4):c.21G>A (p.Glu7=)|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12","1160538|NM_000075.4(CDK4):c.264G>A (p.Lys88=)|single nucleotide variant|Benign/Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1177716|NM_000075.4(CDK4):c.-19-56C>G|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1182049|NM_000075.4(CDK4):c.819+111G>T|single nucleotide variant|Benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1188699|NM_000075.4(CDK4):c.820-224C>G|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1190050|NM_000075.4(CDK4):c.633-200T>A|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1192966|NM_000075.4(CDK4):c.820-94A>G|single nucleotide variant|Likely benign|CDK4|criteria provided, multiple submitters, no conflicts|12","1195707|NM_000075.4(CDK4):c.633-215G>A|single nucleotide variant|Likely benign|CDK4|criteria provided, single submitter|12"]}]}