{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:270,10,HGNC:270,35,0]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:270","source":"HGNC:270|poly(ADP-ribose) polymerase 1","targets":["1261945|NM_001618.4(PARP1):c.2285T>C (p.Val762Ala)|single nucleotide variant|Benign|PARP1|criteria provided, multiple submitters, no conflicts|1","2205461|NM_001618.4(PARP1):c.1840T>C (p.Phe614Leu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2205462|NM_001618.4(PARP1):c.1842C>A (p.Phe614Leu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2216601|NM_001618.4(PARP1):c.482G>T (p.Gly161Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2254608|NM_001618.4(PARP1):c.159C>A (p.His53Gln)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2263329|NM_001618.4(PARP1):c.472T>C (p.Tyr158His)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2263390|NM_001618.4(PARP1):c.1190C>T (p.Thr397Ile)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2270980|NM_001618.4(PARP1):c.1231A>G (p.Met411Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2272498|NM_001618.4(PARP1):c.845G>A (p.Arg282Gln)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2282750|NM_001618.4(PARP1):c.2599A>C (p.Thr867Pro)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2285831|NM_001618.4(PARP1):c.2342G>A (p.Gly781Glu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2286796|NM_001618.4(PARP1):c.1151C>T (p.Ala384Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2296528|NM_001618.4(PARP1):c.427A>G (p.Met143Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2305903|NM_001618.4(PARP1):c.554G>A (p.Ser185Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2320838|NM_001618.4(PARP1):c.1178T>C (p.Met393Thr)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2328794|NM_001618.4(PARP1):c.886G>A (p.Glu296Lys)|single nucleotide variant|Likely benign|PARP1|criteria provided, single submitter|1","2411502|NM_001618.4(PARP1):c.467G>A (p.Arg156His)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2477383|NM_001618.4(PARP1):c.437C>T (p.Pro146Leu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2487760|NM_001618.4(PARP1):c.1019G>A (p.Arg340Gln)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2509307|NM_001618.4(PARP1):c.1114T>C (p.Ser372Pro)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2518222|NM_001618.4(PARP1):c.97C>T (p.Leu33Phe)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2519170|NM_001618.4(PARP1):c.521C>G (p.Pro174Arg)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2527729|NM_001618.4(PARP1):c.2176G>A (p.Asp726Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","2598988|NM_001618.4(PARP1):c.2204G>A (p.Arg735His)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3034622|NM_001618.4(PARP1):c.659C>T (p.Ala220Val)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3035978|NM_001618.4(PARP1):c.14C>G (p.Ser5Trp)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3039691|NM_001618.4(PARP1):c.1148C>A (p.Ser383Tyr)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3040063|NM_001618.4(PARP1):c.2593A>C (p.Arg865=)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3041509|NM_001618.4(PARP1):c.2819A>G (p.Lys940Arg)|single nucleotide variant|Benign|PARP1|no assertion criteria provided|1","3045973|NM_001618.4(PARP1):c.656T>C (p.Val219Ala)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3058577|NM_001618.4(PARP1):c.2916G>A (p.Gly972=)|single nucleotide variant|Likely benign|PARP1|no assertion criteria provided|1","3059377|NM_001618.4(PARP1):c.287-6C>A|single nucleotide variant|Benign|PARP1|no assertion criteria provided|1","3208668|NM_001618.4(PARP1):c.1747T>C (p.Tyr583His)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3208669|NM_001618.4(PARP1):c.1792A>G (p.Ser598Gly)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3208670|NM_001618.4(PARP1):c.2161T>C (p.Ser721Pro)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3208671|NM_001618.4(PARP1):c.2741A>G (p.Asp914Gly)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3208672|NM_001618.4(PARP1):c.2897G>A (p.Gly966Asp)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3208674|NM_001618.4(PARP1):c.563C>T (p.Ala188Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3304344|NM_001618.4(PARP1):c.1271A>G (p.Asn424Ser)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3304345|NM_001618.4(PARP1):c.2444G>A (p.Arg815Lys)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3304347|NM_001618.4(PARP1):c.1793G>A (p.Ser598Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3304348|NM_001618.4(PARP1):c.2945C>G (p.Thr982Ser)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3304349|NM_001618.4(PARP1):c.859A>G (p.Met287Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414186|NM_001618.4(PARP1):c.592C>G (p.Gln198Glu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414187|NM_001618.4(PARP1):c.1171T>G (p.Ser391Ala)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414188|NM_001618.4(PARP1):c.95C>T (p.Ser32Leu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414190|NM_001618.4(PARP1):c.2236A>G (p.Met746Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414192|NM_001618.4(PARP1):c.371C>T (p.Thr124Met)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3414193|NM_001618.4(PARP1):c.2417G>A (p.Arg806Lys)|single nucleotide variant|Likely benign|PARP1|criteria provided, single submitter|1","3414194|NM_001618.4(PARP1):c.1874C>T (p.Ala625Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885672|NM_001618.4(PARP1):c.186C>G (p.His62Gln)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885675|NM_001618.4(PARP1):c.2527G>A (p.Gly843Ser)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885676|NM_001618.4(PARP1):c.628G>A (p.Gly210Ser)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885678|NM_001618.4(PARP1):c.3029A>G (p.Lys1010Arg)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885679|NM_001618.4(PARP1):c.851C>T (p.Ala284Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885680|NM_001618.4(PARP1):c.940G>A (p.Asp314Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3885682|NM_001618.4(PARP1):c.47G>A (p.Ser16Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3905751|NM_001618.4(PARP1):c.1236T>G (p.Ile412Met)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3927961|NM_001618.4(PARP1):c.103A>G (p.Met35Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3927962|NM_001618.4(PARP1):c.2932G>T (p.Gly978Cys)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3927964|NM_001618.4(PARP1):c.1266G>A (p.Thr422=)|single nucleotide variant|Likely benign|PARP1|criteria provided, single submitter|1","3927965|NM_001618.4(PARP1):c.1906A>G (p.Lys636Glu)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","3927966|NM_001618.4(PARP1):c.2194C>A (p.Leu732Ile)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131019|NM_001618.4(PARP1):c.2434G>A (p.Glu812Lys)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131020|NM_001618.4(PARP1):c.2803G>A (p.Ala935Thr)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131021|NM_001618.4(PARP1):c.2168G>A (p.Gly723Asp)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131023|NM_001618.4(PARP1):c.1253A>T (p.Lys418Met)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131024|NM_001618.4(PARP1):c.2560C>G (p.Leu854Val)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131025|NM_001618.4(PARP1):c.2243A>G (p.Lys748Arg)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131026|NM_001618.4(PARP1):c.2981T>C (p.Ile994Thr)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131027|NM_001618.4(PARP1):c.623G>A (p.Arg208Lys)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131029|NM_001618.4(PARP1):c.832G>T (p.Ala278Ser)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131030|NM_001618.4(PARP1):c.2227G>A (p.Asp743Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4131036|NM_001618.4(PARP1):c.1080A>C (p.Glu360Asp)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4284797|NM_001618.4(PARP1):c.2062del (p.Glu688fs)|Deletion||PARP1||1","4376398|NM_001618.4(PARP1):c.2964-7C>A|single nucleotide variant||PARP1||1","4376406|NM_001618.4(PARP1):c.2786+138A>G|single nucleotide variant||PARP1||1","4376438|NM_001618.4(PARP1):c.2659-11C>A|single nucleotide variant||PARP1||1","4376443|NM_001618.4(PARP1):c.2410G>T (p.Val804Phe)|single nucleotide variant||PARP1||1","4376453|NM_001618.4(PARP1):c.2277+3A>T|single nucleotide variant||PARP1||1","4376458|NM_001618.4(PARP1):c.2160G>T (p.Val720=)|single nucleotide variant||PARP1||1","4376460|NM_001618.4(PARP1):c.2157G>A (p.Ala719=)|single nucleotide variant||PARP1||1","4376466|NM_001618.4(PARP1):c.2155-92G>T|single nucleotide variant||PARP1||1","4376493|NM_001618.4(PARP1):c.2038G>A (p.Glu680Lys)|single nucleotide variant||PARP1||1","4376522|NM_001618.4(PARP1):c.1229C>T (p.Ala410Val)|single nucleotide variant||PARP1||1","4376530|NM_001618.4(PARP1):c.1160-205G>T|single nucleotide variant||PARP1||1","4376535|NM_001618.4(PARP1):c.1012G>T (p.Glu338Ter)|single nucleotide variant||PARP1||1","4376542|NM_001618.4(PARP1):c.1012G>C (p.Glu338Gln)|single nucleotide variant||PARP1||1","4376549|NM_001618.4(PARP1):c.1012-265G>T|single nucleotide variant||PARP1||1","4376555|NM_001618.4(PARP1):c.1011+2T>G|single nucleotide variant||PARP1||1","4376563|NM_001618.4(PARP1):c.1011+2T>C|single nucleotide variant||PARP1||1","4376564|NM_001618.4(PARP1):c.1011+2T>A|single nucleotide variant||PARP1||1","4376568|NM_001618.4(PARP1):c.942C>G (p.Asp314Glu)|single nucleotide variant||PARP1||1","4376635|NM_001618.4(PARP1):c.285A>T (p.Thr95=)|single nucleotide variant||PARP1||1","4376639|NM_001618.4(PARP1):c.-77C>G|single nucleotide variant||PARP1||1","4564577|NM_001618.4(PARP1):c.2262T>A (p.Asn754Lys)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4564579|NM_001618.4(PARP1):c.2636T>G (p.Ile879Arg)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4564580|NM_001618.4(PARP1):c.426G>T (p.Lys142Asn)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4564581|NM_001618.4(PARP1):c.700C>T (p.Leu234Phe)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1","4564582|NM_001618.4(PARP1):c.2238G>T (p.Met746Ile)|single nucleotide variant|Uncertain significance|PARP1|criteria provided, single submitter|1"]}]}