{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:391,10,HGNC:391,100,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:391","source":"HGNC:391|AKT serine/threonine kinase 1","targets":["1002469|NM_001382430.1(AKT1):c.1088T>C (p.Met363Thr)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, multiple submitters, no conflicts|14","1003666|NM_001382430.1(AKT1):c.1173-6C>G|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1005578|NM_001382430.1(AKT1):c.1097T>C (p.Ile366Thr)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1006787|NM_001382430.1(AKT1):c.1436C>T (p.Thr479Met)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1009277|NM_001382430.1(AKT1):c.16A>G (p.Ile6Val)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1009874|NM_001382430.1(AKT1):c.1440C>G (p.Ala480=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1014444|NM_001382430.1(AKT1):c.567+5G>T|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1016933|NM_001382430.1(AKT1):c.1277A>C (p.Lys426Thr)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1018655|NM_001382430.1(AKT1):c.1393C>T (p.Arg465Cys)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1022066|NM_001382430.1(AKT1):c.1260+1G>C|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1023845|NM_001382430.1(AKT1):c.1130A>G (p.Lys377Arg)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, multiple submitters, no conflicts|14","1031512|NM_001382430.1(AKT1):c.1351C>T (p.Pro451Ser)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1035242|NM_001382430.1(AKT1):c.349G>A (p.Glu117Lys)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1035310|NM_001382430.1(AKT1):c.749C>T (p.Ala250Val)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1037529|NM_001382430.1(AKT1):c.719C>G (p.Ser240Cys)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, multiple submitters, no conflicts|14","1039217|NM_001382430.1(AKT1):c.661G>A (p.Asp221Asn)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1039404|NM_001382430.1(AKT1):c.983G>A (p.Arg328His)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1040994|NM_001382430.1(AKT1):c.1372A>G (p.Met458Val)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, multiple submitters, no conflicts|14","1042487|NM_001382430.1(AKT1):c.954C>A (p.Pro318=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1046456|NM_001382430.1(AKT1):c.957+3G>T|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1053790|NM_001382430.1(AKT1):c.641A>G (p.Lys214Arg)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, single submitter|14","1058918|NM_001382430.1(AKT1):c.374C>T (p.Pro125Leu)|single nucleotide variant|Uncertain significance|AKT1|criteria provided, multiple submitters, no conflicts|14","1083107|NM_001382430.1(AKT1):c.1080C>T (p.Leu360=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1096212|NM_001382430.1(AKT1):c.47-4G>T|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1103014|NM_001382430.1(AKT1):c.412C>T (p.Leu138=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1107585|NM_001382430.1(AKT1):c.1176T>C (p.Leu392=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1108424|NM_001382430.1(AKT1):c.1172+9C>A|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1109184|NM_001382430.1(AKT1):c.1113G>C (p.Thr371=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1110889|NM_001382430.1(AKT1):c.1119T>A (p.Gly373=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1113078|NM_001382430.1(AKT1):c.978C>T (p.Tyr326=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1113747|NM_001382430.1(AKT1):c.747G>T (p.Arg249=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1113813|NM_001382430.1(AKT1):c.357C>T (p.Asp119=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1118597|NM_001382430.1(AKT1):c.633+7G>T|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1118976|NM_001382430.1(AKT1):c.1113G>A (p.Thr371=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1122647|NM_001382430.1(AKT1):c.1248G>A (p.Val416=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1123356|NM_001382430.1(AKT1):c.927T>C (p.Phe309=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1126278|NM_001382430.1(AKT1):c.1437G>A (p.Thr479=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1126893|NM_001382430.1(AKT1):c.309C>T (p.Ile103=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1128057|NM_001382430.1(AKT1):c.561G>A (p.Val187=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1128750|NM_001382430.1(AKT1):c.957+7G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1132752|NM_001382430.1(AKT1):c.750C>G (p.Ala250=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1133109|NM_001382430.1(AKT1):c.1011G>A (p.Val337=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1134032|NM_001382430.1(AKT1):c.1261-10A>C|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1136296|NM_001382430.1(AKT1):c.1107G>C (p.Pro369=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1136308|NM_001382430.1(AKT1):c.1083C>T (p.Ile361=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1140873|NM_001382430.1(AKT1):c.288-4G>T|single nucleotide variant|Conflicting classifications of pathogenicity|AKT1|criteria provided, conflicting classifications|14","1142762|NM_001382430.1(AKT1):c.1146G>A (p.Gly382=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1149118|NM_001382430.1(AKT1):c.1149G>A (p.Leu383=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1150037|NM_001382430.1(AKT1):c.552A>G (p.Glu184=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1150665|NM_001382430.1(AKT1):c.6C>T (p.Ser2=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1152607|NM_001382430.1(AKT1):c.684G>A (p.Glu228=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1152993|NM_001382430.1(AKT1):c.43C>A (p.Arg15=)|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1153354|NM_001382430.1(AKT1):c.1419C>G (p.Ser473=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1154574|NM_001382430.1(AKT1):c.444C>T (p.Asn148=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1156017|NM_001382430.1(AKT1):c.47-4G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1160719|NM_001382430.1(AKT1):c.633+9G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1161933|NM_001382430.1(AKT1):c.252C>T (p.Ile84=)|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1174307|NM_001382430.1(AKT1):c.47-76C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1174492|NM_001382430.1(AKT1):c.653A>C (p.Gln218Pro)|single nucleotide variant|Uncertain significance|AKT1|no assertion criteria provided|14","1178734|NM_001382430.1(AKT1):c.634-213A>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1182199|NM_001382430.1(AKT1):c.46+43G>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1187314|NM_001382430.1(AKT1):c.567+14G>A|single nucleotide variant|Benign/Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1189582|NM_001382430.1(AKT1):c.1261-196C>T|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1201071|NM_001382430.1(AKT1):c.1172+71G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1202658|NM_001382430.1(AKT1):c.1172+207C>T|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1203922|NM_001382430.1(AKT1):c.288-121G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1207299|NM_001382430.1(AKT1):c.1260+190C>T|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1207622|NM_001382430.1(AKT1):c.-45C>G|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1208657|NM_001382430.1(AKT1):c.703-125G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1213011|NM_001382430.1(AKT1):c.176-245C>A|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1213239|NM_001382430.1(AKT1):c.47-319T>C|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1214756|NM_001382430.1(AKT1):c.176-261G>A|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1220388|NM_001382430.1(AKT1):c.1260+93C>T|single nucleotide variant|Likely benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1221497|NM_001382430.1(AKT1):c.436-63C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1221534|NM_001382430.1(AKT1):c.287+170G>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1223783|NM_001382430.1(AKT1):c.288-321C>T|single nucleotide variant|Likely benign|AKT1|criteria provided, single submitter|14","1229300|NM_001382430.1(AKT1):c.1260+66C>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1232426|NM_001382430.1(AKT1):c.288-281_288-265del|Deletion|Benign|AKT1|criteria provided, single submitter|14","1232529|NM_001382430.1(AKT1):c.47-139A>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1235192|NM_001382430.1(AKT1):c.1173-165G>A|single nucleotide variant|Benign|AKT1|criteria provided, single submitter|14","1235718|NM_001382430.1(AKT1):c.1172+23A>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1237020|NM_001382430.1(AKT1):c.1260+98G>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1238585|NM_001382430.1(AKT1):c.46+42T>C|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1247026|NM_001382430.1(AKT1):c.1363+52_1363+55del|Microsatellite|Benign|AKT1|criteria provided, single submitter|14","1247143|NM_001382430.1(AKT1):c.702+138C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1258466|NM_001382430.1(AKT1):c.288-273T>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1261565|NM_001382430.1(AKT1):c.436-32C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1262120|NM_001382430.1(AKT1):c.47-128C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1264628|NM_001382430.1(AKT1):c.176-113C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1264691|NM_001382430.1(AKT1):c.288-309_288-270del|Deletion|Benign|AKT1|criteria provided, single submitter|14","1267356|NM_001382430.1(AKT1):c.287+165G>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1268436|NM_001382430.1(AKT1):c.176-328C>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1270243|NM_001382430.1(AKT1):c.287+170G>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1270391|NM_001382430.1(AKT1):c.702+33C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1270593|NM_001382430.1(AKT1):c.1260+32G>A|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1272355|NM_001382430.1(AKT1):c.287+30A>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1274406|NM_001382430.1(AKT1):c.288-238C>T|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1280802|NM_001382430.1(AKT1):c.1173-31C>G|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14","1281566|NM_001382430.1(AKT1):c.288-289dup|Duplication|Benign|AKT1|criteria provided, single submitter|14","1281623|NM_001382430.1(AKT1):c.1172+69G>C|single nucleotide variant|Benign|AKT1|criteria provided, multiple submitters, no conflicts|14"]}]}