{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:5382,10,HGNC:5382,58,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:5382","source":"HGNC:5382|isocitrate dehydrogenase (NADP(+)) 1","targets":["1172783|NM_005896.4(IDH1):c.890G>T (p.Cys297Phe)|single nucleotide variant|Likely pathogenic|IDH1|criteria provided, single submitter|2","1228093|NM_005896.4(IDH1):c.1154+300C>T|single nucleotide variant|Benign|IDH1|criteria provided, single submitter|2","1232855|NM_005896.4(IDH1):c.992-273T>C|single nucleotide variant|Benign|IDH1|criteria provided, single submitter|2","1250304|NM_005896.4(IDH1):c.415-123del|Deletion|Benign|IDH1|criteria provided, single submitter|2","1261748|NM_005896.4(IDH1):c.415-141_415-140dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1263012|NM_005896.4(IDH1):c.520+27dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1266090|NM_005896.4(IDH1):c.699-241C>A|single nucleotide variant|Benign|IDH1|criteria provided, multiple submitters, no conflicts|2","1271012|NM_005896.4(IDH1):c.415-141dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1273575|NM_005896.4(IDH1):c.415-141_415-138dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1274994|NM_005896.4(IDH1):c.122+105G>A|single nucleotide variant|Benign|IDH1|criteria provided, multiple submitters, no conflicts|2","1275091|NM_005896.4(IDH1):c.1155-225_1155-224insGA|Insertion|Benign|IDH1|criteria provided, single submitter|2","1287620|NM_005896.4(IDH1):c.122+166dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1295204|NM_005896.4(IDH1):c.415-141_415-139dup|Duplication|Benign|IDH1|criteria provided, single submitter|2","1295248|NM_005896.4(IDH1):c.415-238A>G|single nucleotide variant|Benign|IDH1|criteria provided, multiple submitters, no conflicts|2","134515|NM_005896.4(IDH1):c.94T>G (p.Phe32Val)|single nucleotide variant|Likely benign|IDH1|criteria provided, multiple submitters, no conflicts|2","134516|NM_005896.4(IDH1):c.211G>A (p.Val71Ile)|single nucleotide variant|Benign|IDH1|criteria provided, multiple submitters, no conflicts|2","134517|NM_005896.4(IDH1):c.548A>G (p.Tyr183Cys)|single nucleotide variant|Benign|IDH1|criteria provided, single submitter|2","134518|NM_005896.4(IDH1):c.565A>G (p.Ile189Val)|single nucleotide variant|Likely pathogenic|IDH1|criteria provided, single submitter|2","134519|NM_005896.4(IDH1):c.659A>G (p.Asp220Gly)|single nucleotide variant|not provided|IDH1|no classification provided|2","134520|NM_005896.4(IDH1):c.532G>A (p.Val178Ile)|single nucleotide variant|Benign|IDH1|criteria provided, multiple submitters, no conflicts|2","134521|NM_005896.4(IDH1):c.665G>T (p.Arg222Leu)|single nucleotide variant|not provided|IDH1|no classification provided|2","134522|NM_005896.4(IDH1):c.622T>C (p.Tyr208His)|single nucleotide variant|not provided|IDH1|no classification provided|2","156444|NM_005896.4(IDH1):c.395G>A (p.Arg132His)|single nucleotide variant|Pathogenic/Likely pathogenic|IDH1|criteria provided, multiple submitters, no conflicts|2","1727353|NM_005896.4(IDH1):c.307C>T (p.Leu103=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1727573|NM_005896.4(IDH1):c.309G>A (p.Leu103=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1727581|NM_005896.4(IDH1):c.309G>C (p.Leu103=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1727734|NM_005896.4(IDH1):c.310G>A (p.Gly104Ser)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1727972|NM_005896.4(IDH1):c.112G>A (p.Asp38Asn)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, multiple submitters, no conflicts|2","1728275|NM_005896.4(IDH1):c.315C>G (p.Gly105=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1728632|NM_005896.4(IDH1):c.1131T>C (p.Ala377=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1728646|NM_005896.4(IDH1):c.318G>A (p.Thr106=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1728650|NM_005896.4(IDH1):c.318G>C (p.Thr106=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1728653|NM_005896.4(IDH1):c.318G>T (p.Thr106=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1729009|NM_005896.4(IDH1):c.1133C>G (p.Ala378Gly)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1729042|NM_005896.4(IDH1):c.321C>A (p.Val107=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1729056|NM_005896.4(IDH1):c.321C>T (p.Val107=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1729398|NM_005896.4(IDH1):c.324C>T (p.Phe108=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1730057|NM_005896.4(IDH1):c.1137C>T (p.Cys379=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1730799|NM_005896.4(IDH1):c.337A>G (p.Ile113Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1732197|NM_005896.4(IDH1):c.1144G>T (p.Gly382Cys)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1733820|NM_005896.4(IDH1):c.114T>C (p.Asp38=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1734587|NM_005896.4(IDH1):c.1153A>G (p.Asn385Asp)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1735018|NM_005896.4(IDH1):c.379C>T (p.Pro127Ser)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1735302|NM_005896.4(IDH1):c.1155T>C (p.Asn385=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1735429|NM_005896.4(IDH1):c.383T>C (p.Ile128Thr)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1735505|NM_005896.4(IDH1):c.384C>T (p.Ile128=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1735697|NM_005896.4(IDH1):c.386T>G (p.Ile129Ser)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1735781|NM_005896.4(IDH1):c.387C>G (p.Ile129Met)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1736013|NM_005896.4(IDH1):c.38T>C (p.Met13Thr)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1736344|NM_005896.4(IDH1):c.393T>A (p.Gly131=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1736752|NM_005896.4(IDH1):c.398A>T (p.His133Leu)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1736887|NM_005896.4(IDH1):c.39G>T (p.Met13Ile)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1737094|NM_005896.4(IDH1):c.401C>T (p.Ala134Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1737817|NM_005896.4(IDH1):c.409G>A (p.Asp137Asn)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1738883|NM_005896.4(IDH1):c.422C>T (p.Ala141Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1739062|NM_005896.4(IDH1):c.424A>G (p.Thr142Ala)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1739806|NM_005896.4(IDH1):c.1171T>C (p.Tyr391His)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1739855|NM_005896.4(IDH1):c.433G>T (p.Val145Phe)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1740225|NM_005896.4(IDH1):c.438T>C (p.Val146=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1740282|NM_005896.4(IDH1):c.439C>T (p.Pro147Ser)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1740687|NM_005896.4(IDH1):c.444G>A (p.Gly148=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1740883|NM_005896.4(IDH1):c.1176G>T (p.Leu392Phe)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1740961|NM_005896.4(IDH1):c.448G>A (p.Gly150Arg)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1741678|NM_005896.4(IDH1):c.117A>G (p.Leu39=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1742461|NM_005896.4(IDH1):c.468C>T (p.Tyr156=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1742547|NM_005896.4(IDH1):c.46G>C (p.Asp16His)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1743060|NM_005896.4(IDH1):c.1015G>A (p.Gly339Arg)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1743258|NM_005896.4(IDH1):c.480C>T (p.Asp160=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1743552|NM_005896.4(IDH1):c.484A>T (p.Thr162Ser)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1743895|NM_005896.4(IDH1):c.489A>G (p.Gln163=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1744265|NM_005896.4(IDH1):c.493G>A (p.Val165Met)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1744889|NM_005896.4(IDH1):c.502C>T (p.Leu168=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1745208|NM_005896.4(IDH1):c.1192A>G (p.Met398Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1745223|NM_005896.4(IDH1):c.1192A>T (p.Met398Leu)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1745404|NM_005896.4(IDH1):c.510T>A (p.His170Gln)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1745453|NM_005896.4(IDH1):c.511A>G (p.Asn171Asp)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1746507|NM_005896.4(IDH1):c.526G>C (p.Gly176Arg)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1746687|NM_005896.4(IDH1):c.52A>G (p.Met18Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1746756|NM_005896.4(IDH1):c.530G>A (p.Gly177Asp)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1746829|NM_005896.4(IDH1):c.531T>G (p.Gly177=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1747011|NM_005896.4(IDH1):c.534T>C (p.Val178=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1747150|NM_005896.4(IDH1):c.537C>T (p.Ala179=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1747730|NM_005896.4(IDH1):c.546G>C (p.Met182Ile)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1748137|NM_005896.4(IDH1):c.552T>A (p.Asn184Lys)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1748305|NM_005896.4(IDH1):c.1017G>A (p.Gly339=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1748489|NM_005896.4(IDH1):c.558T>C (p.Asp186=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1748672|NM_005896.4(IDH1):c.1205G>A (p.Gly402Glu)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1748787|NM_005896.4(IDH1):c.1206A>G (p.Gly402=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1748969|NM_005896.4(IDH1):c.566T>C (p.Ile189Thr)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1749029|NM_005896.4(IDH1):c.567T>G (p.Ile189Met)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1749279|NM_005896.4(IDH1):c.571G>A (p.Asp191Asn)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1749726|NM_005896.4(IDH1):c.57A>C (p.Thr19=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1749946|NM_005896.4(IDH1):c.582C>T (p.His194=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1750137|NM_005896.4(IDH1):c.585T>C (p.Ser195=)|single nucleotide variant|Likely benign|IDH1|criteria provided, single submitter|2","1750380|NM_005896.4(IDH1):c.58C>G (p.Arg20Gly)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1750484|NM_005896.4(IDH1):c.591C>G (p.Phe197Leu)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1750713|NM_005896.4(IDH1):c.595A>G (p.Met199Val)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1750901|NM_005896.4(IDH1):c.598G>T (p.Ala200Ser)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1750935|NM_005896.4(IDH1):c.599C>G (p.Ala200Gly)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2","1750970|NM_005896.4(IDH1):c.59G>T (p.Arg20Leu)|single nucleotide variant|Uncertain significance|IDH1|criteria provided, single submitter|2"]}]}