{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:6081,10,HGNC:6081,157,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:6081","source":"HGNC:6081|insulin","targets":["1049511|NM_000207.3(INS):c.227G>A (p.Ser76Asn)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","1162205|NM_000207.3(INS):c.115C>T (p.Leu39Phe)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1232756|NM_000207.3(INS):c.188-111C>T|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1239524|NM_000207.3(INS):c.188-168G>C|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1252995|NM_000207.2(INS):c.-463_-451del|Deletion|Benign|INS|criteria provided, multiple submitters, no conflicts|11","1261033|NM_000207.3(INS):c.-18+38A>G|single nucleotide variant|Benign|INS|criteria provided, multiple submitters, no conflicts|11","1265784|NC_000011.10:g.2159615G>A|single nucleotide variant|Benign|INS|criteria provided, multiple submitters, no conflicts|11","1269776|NC_000011.10:g.2159542C>T|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1275239|NC_000011.10:g.2159566C>A|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1291923|NC_000011.10:g.2161265C>G|single nucleotide variant|Benign|INS|criteria provided, multiple submitters, no conflicts|11","129279|NM_000207.3(INS):c.188-10G>A|single nucleotide variant|Benign/Likely benign|INS|criteria provided, multiple submitters, no conflicts|11","1317682|NM_000207.3(INS):c.-153C>G|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","1336035|NM_000207.2(INS):c.-379_-372dup|Duplication|Benign|INS|criteria provided, single submitter|11","1336162|NM_000207.2(INS):c.-146A>C|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","1336428|NM_000207.2(INS):c.-449_-443del|Deletion|Benign|INS|criteria provided, single submitter|11","1336487|NM_000207.3(INS):c.289A>C (p.Thr97Pro)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1336658|NM_000207.3(INS):c.-46A>G|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1336686|NM_000207.3(INS):c.187+271A>G|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1336720|NM_000207.2(INS):c.-293C>T|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1336766|NM_000207.3(INS):c.-17-74T>C|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1337065|NM_000207.3(INS):c.188-233C>T|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1337069|NM_000207.2(INS):c.-485_-430del|Deletion|Benign|INS|criteria provided, single submitter|11","1337077|NM_000207.2(INS):c.-88A>G|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1337186|NM_000207.3(INS):c.188-97C>T|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1337288|NM_000207.3(INS):c.187+203G>A|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","1337436|NM_000207.3(INS):c.147C>T (p.Phe49=)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","1337581|NM_000207.3(INS):c.188-114G>T|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","1337685|NM_000207.3(INS):c.188-137A>T|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","13378|NM_000207.3(INS):c.143T>C (p.Phe48Ser)|single nucleotide variant|Pathogenic|INS|no assertion criteria provided|11","13379|NM_000207.3(INS):c.100C>G (p.His34Asp)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","13382|NM_000207.3(INS):c.266G>T (p.Arg89Leu)|single nucleotide variant|Pathogenic|INS|no assertion criteria provided|11","13383|NM_000207.3(INS):c.266G>C (p.Arg89Pro)|single nucleotide variant|Pathogenic|INS|no assertion criteria provided|11","1338622|NM_000207.3(INS):c.95G>T (p.Gly32Val)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1338640|NM_000207.3(INS):c.103C>G (p.Leu35Val)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","13387|NM_000207.3(INS):c.287G>A (p.Cys96Tyr)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","13389|NM_000207.3(INS):c.143T>G (p.Phe48Cys)|single nucleotide variant|Likely pathogenic/Likely risk allele|INS|criteria provided, multiple submitters, no conflicts|11","13390|NM_000207.3(INS):c.16C>T (p.Arg6Cys)|single nucleotide variant|Likely risk allele|INS|criteria provided, single submitter|11","13391|NM_000207.3(INS):c.137G>A (p.Arg46Gln)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","13392|NM_000207.3(INS):c.163C>T (p.Arg55Cys)|single nucleotide variant|Pathogenic/Likely pathogenic/Likely risk allele|INS|criteria provided, multiple submitters, no conflicts|11","1359577|NM_000207.3(INS):c.91T>G (p.Cys31Gly)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1455986|NM_000207.3(INS):c.1A>G (p.Met1Val)|single nucleotide variant|Pathogenic/Likely pathogenic|INS|criteria provided, multiple submitters, no conflicts|11","1457228|NC_000011.9:g.(?_2181023)_(2193087_?)del|Deletion|Pathogenic|INS|criteria provided, single submitter|11","1459937|NC_000011.9:g.(?_2181023)_(2182533_?)del|Deletion|Pathogenic|INS|criteria provided, single submitter|11","1526009|NM_000207.3(INS):c.293G>T (p.Ser98Ile)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1526010|NM_000207.3(INS):c.322T>G (p.Tyr108Asp)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1526012|NM_000207.3(INS):c.101A>C (p.His34Pro)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1526013|NM_000207.3(INS):c.103C>A (p.Leu35Met)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1678636|NM_000207.3(INS):c.155C>A (p.Pro52His)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1715602|NM_000207.3(INS):c.29T>A (p.Leu10Gln)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1718014|NM_000207.3(INS):c.212G>C (p.Gly71Ala)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","1774163|NM_000207.3(INS):c.150C>T (p.Tyr50=)|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","1801848|NM_000207.3(INS):c.187+15C>T|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1801850|NM_000207.3(INS):c.155C>G (p.Pro52Arg)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","1801851|NM_000207.3(INS):c.153A>C (p.Thr51=)|single nucleotide variant|Benign/Likely benign|INS|criteria provided, multiple submitters, no conflicts|11","1900945|NM_000207.3(INS):c.188-11C>T|single nucleotide variant|Benign|INS|criteria provided, single submitter|11","1948092|NM_000207.3(INS):c.194A>G (p.Gln65Arg)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2054798|NM_000207.3(INS):c.207C>T (p.Gly69=)|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","21115|NM_000207.3(INS):c.140G>T (p.Gly47Val)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","21118|NM_000207.3(INS):c.268G>T (p.Gly90Cys)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","211186|NM_000207.3(INS):c.188-31G>A|single nucleotide variant|Pathogenic/Likely risk allele|INS|criteria provided, multiple submitters, no conflicts|11","21120|NM_000207.3(INS):c.323A>G (p.Tyr108Cys)|single nucleotide variant|Likely risk allele|INS|criteria provided, single submitter|11","21122|NM_000207.3(INS):c.94G>A (p.Gly32Ser)|single nucleotide variant|Pathogenic/Likely pathogenic|INS|criteria provided, multiple submitters, no conflicts|11","21123|NM_000207.3(INS):c.94G>C (p.Gly32Arg)|single nucleotide variant|not provided|INS|no classification provided|11","2152100|NM_000207.3(INS):c.277G>A (p.Glu93Lys)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","2179727|NM_000207.3(INS):c.48C>G (p.Leu16=)|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","2284265|NM_001042376.3(INS-IGF2):c.145T>C (p.Phe49Leu)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2311109|NM_001042376.3(INS-IGF2):c.52G>C (p.Gly18Arg)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2428828|NM_000207.3(INS):c.188-5_188-4insGCGCAGTGGGGCACCTGCCACTGCGC|Microsatellite|Uncertain significance|INS|criteria provided, multiple submitters, no conflicts|11","2443149|NM_000207.3(INS):c.187+391C>T|single nucleotide variant|Likely benign|INS|no assertion criteria provided|11","2443150|NM_000207.3(INS):c.299G>A (p.Cys100Tyr)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","253331|NM_000207.3(INS):c.125T>C (p.Val42Ala)|single nucleotide variant|Pathogenic/Likely pathogenic|INS|criteria provided, multiple submitters, no conflicts|11","253743|GRCh37/hg19 11p15.5(chr11:2181002-2182229)x1|copy number loss|Uncertain significance|INS|criteria provided, single submitter|11","255531|NM_000207.3(INS):c.*9C>T|single nucleotide variant|Benign/Likely benign|INS|criteria provided, multiple submitters, no conflicts|11","255532|NM_000207.3(INS):c.187+11T>C|single nucleotide variant|Benign/Likely benign|INS|criteria provided, multiple submitters, no conflicts|11","255533|NM_000207.3(INS):c.63A>G (p.Pro21=)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","2630345|NM_000207.3(INS):c.136C>T (p.Arg46Ter)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","2630683|NM_000207.3(INS):c.188-43C>T|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2631502|NM_000207.3(INS):c.284G>A (p.Cys95Tyr)|single nucleotide variant|Likely pathogenic|INS|criteria provided, single submitter|11","263251|NM_000360.4(TH):c.1200+9C>T|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","2634300|NM_000207.3(INS):c.-152C>T|single nucleotide variant|Uncertain significance|INS|criteria provided, multiple submitters, no conflicts|11","2636035|NM_000207.3(INS):c.206G>A (p.Gly69Asp)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2664354|NM_000207.3(INS):c.104T>A (p.Leu35Gln)|single nucleotide variant|Likely risk allele|INS|criteria provided, single submitter|11","268153|NM_000207.3(INS):c.187+241G>A|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2694226|NM_000207.3(INS):c.316_318del (p.Glu106del)|Deletion|Uncertain significance|INS|criteria provided, single submitter|11","2822542|NM_000207.3(INS):c.249G>A (p.Glu83=)|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","2856439|NM_000207.3(INS):c.272T>C (p.Ile91Thr)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2862531|NM_000207.3(INS):c.317A>T (p.Glu106Val)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","2956324|NM_000207.3(INS):c.15G>A (p.Met5Ile)|single nucleotide variant|Uncertain significance|INS|criteria provided, single submitter|11","3020391|NM_000207.3(INS):c.188-17G>A|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","3029536|NM_000207.3(INS):c.*49G>A|single nucleotide variant|Likely benign|INS|no assertion criteria provided|11","3031610|NM_000207.3(INS):c.279A>G (p.Glu93=)|single nucleotide variant|Likely benign|INS|criteria provided, single submitter|11","3033630|NM_000207.3(INS):c.224G>A (p.Gly75Asp)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","3035689|NM_000207.3(INS):c.187+245C>T|single nucleotide variant|Likely benign|INS|no assertion criteria provided|11","3036718|NM_000207.3(INS):c.187+6C>G|single nucleotide variant|Likely benign|INS|no assertion criteria provided|11","304049|NM_000207.3(INS):c.*42C>T|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","304050|NM_000207.3(INS):c.*28G>A|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","304051|NM_000207.3(INS):c.*22A>C|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","304052|NM_000207.3(INS):c.*2C>T|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","304053|NM_000207.3(INS):c.188-3C>A|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11","304054|NM_000207.3(INS):c.153A>G (p.Thr51=)|single nucleotide variant|Conflicting classifications of pathogenicity|INS|criteria provided, conflicting classifications|11"]}]}