{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:6407,10,HGNC:6407,118,0]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:6407","source":"HGNC:6407|KRAS proto-oncogene, GTPase","targets":["1016209|NM_004985.5(KRAS):c.214A>C (p.Met72Leu)|single nucleotide variant|Likely pathogenic|KRAS|criteria provided, single submitter|12","1028518|NM_033360.4(KRAS):c.559A>G (p.Ile187Val)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1038615|NM_004985.5(KRAS):c.16C>G (p.Leu6Val)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1046139|NM_004985.5(KRAS):c.388_389delinsAT (p.Ala130Ile)|Indel|Uncertain significance|KRAS|criteria provided, multiple submitters, no conflicts|12","1047419|NM_004985.5(KRAS):c.352T>C (p.Cys118Arg)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, multiple submitters, no conflicts|12","1049055|NM_004985.5(KRAS):c.30A>G (p.Gly10=)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1049331|NM_004985.5(KRAS):c.19G>A (p.Val7Met)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1049359|NM_004985.5(KRAS):c.22G>A (p.Val8Ile)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1049563|NM_004985.5(KRAS):c.18T>C (p.Leu6=)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1049753|NM_004985.5(KRAS):c.45C>T (p.Gly15=)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1050425|NM_004985.5(KRAS):c.75_80del (p.Gln25_Asn26del)|Deletion|Uncertain significance|KRAS|no assertion criteria provided|12","1050562|NM_004985.5(KRAS):c.74A>G (p.Gln25Arg)|single nucleotide variant|Uncertain significance|KRAS|no assertion criteria provided|12","1065170|NM_004985.5(KRAS):c.112-12C>T|single nucleotide variant|Benign/Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1079653|NM_004985.5(KRAS):c.481C>A (p.Arg161=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1098601|NM_004985.5(KRAS):c.58A>G (p.Thr20Ala)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1113732|NM_004985.5(KRAS):c.535AAG[1] (p.Lys180del)|Microsatellite|Likely benign|KRAS|criteria provided, single submitter|12","1163347|NM_004985.5(KRAS):c.322G>T (p.Asp108Tyr)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, multiple submitters, no conflicts|12","1172833|NM_004985.5(KRAS):c.197_198insTGACCTGCT (p.Ala66_Met67insAspLeuLeu)|Insertion|Pathogenic|KRAS|criteria provided, single submitter|12","1177293|NM_004985.5(KRAS):c.197_223dup (p.Ala66_Thr74dup)|Duplication|Likely pathogenic|KRAS|criteria provided, single submitter|12","1189384|NM_004985.5(KRAS):c.291-128T>G|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1191328|NM_004985.5(KRAS):c.229G>A (p.Gly77Ser)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1192108|NM_004985.5(KRAS):c.451-5327G>A|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1199628|NM_004985.5(KRAS):c.-11-324T>G|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1203835|NM_004985.5(KRAS):c.-12+116G>T|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1212481|NM_004985.5(KRAS):c.450+296T>A|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1218871|NM_004985.5(KRAS):c.411T>C (p.Tyr137=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1219169|NM_004985.5(KRAS):c.450+304T>A|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1219824|NM_004985.5(KRAS):c.346A>C (p.Asn116His)|single nucleotide variant|Pathogenic|KRAS|criteria provided, single submitter|12","1233405|NM_004985.5(KRAS):c.450+308_450+322del|Deletion|Benign|KRAS|criteria provided, single submitter|12","1234106|NM_033360.4(KRAS):c.450+40A>G|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","1235060|NM_004985.5(KRAS):c.-190C>T|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","1239850|NM_004985.5(KRAS):c.456T>G (p.Val152=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1244733|NM_004985.5(KRAS):c.450+300_450+322del|Deletion|Benign|KRAS|criteria provided, single submitter|12","1246048|NM_004985.5(KRAS):c.450+298_450+322del|Deletion|Benign|KRAS|criteria provided, single submitter|12","1247750|NM_033360.4(KRAS):c.450+92A>G|single nucleotide variant|Benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1253268|NM_033360.4(KRAS):c.290+74T>G|single nucleotide variant|Benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1253667|NM_004985.5(KRAS):c.450+306_450+322del|Deletion|Benign|KRAS|criteria provided, single submitter|12","12578|NM_004985.5(KRAS):c.34G>T (p.Gly12Cys)|single nucleotide variant|Likely pathogenic|KRAS|criteria provided, single submitter|12","12579|NM_004985.5(KRAS):c.34G>C (p.Gly12Arg)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12580|NM_004985.5(KRAS):c.38G>A (p.Gly13Asp)|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12581|NM_033360.4(KRAS):c.175G>A (p.Ala59Thr)|single nucleotide variant|Pathogenic|KRAS|no assertion criteria provided|12","12582|NM_004985.5(KRAS):c.35G>A (p.Gly12Asp)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12583|NM_004985.5(KRAS):c.35G>T (p.Gly12Val)|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12584|NM_004985.5(KRAS):c.34G>A (p.Gly12Ser)|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12585|NM_033360.4(KRAS):c.27_29dup (p.Gly10dup)|Duplication|Pathogenic|KRAS|no assertion criteria provided|12","12586|NM_004985.5(KRAS):c.178G>C (p.Gly60Arg)|single nucleotide variant|Pathogenic|KRAS|reviewed by expert panel|12","12587|NM_004985.5(KRAS):c.458A>T (p.Asp153Val)|single nucleotide variant|Pathogenic|KRAS|reviewed by expert panel|12","12588|NM_004985.5(KRAS):c.173C>T (p.Thr58Ile)|single nucleotide variant|Pathogenic|KRAS|reviewed by expert panel|12","12589|NM_004985.5(KRAS):c.40G>A (p.Val14Ile)|single nucleotide variant|Pathogenic|KRAS|reviewed by expert panel|12","12590|NM_004985.5(KRAS):c.101C>G (p.Pro34Arg)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12591|NM_033360.4(KRAS):c.*9T>G|single nucleotide variant|Pathogenic|KRAS|no assertion criteria provided|12","12593|NM_004985.5(KRAS):c.37G>C (p.Gly13Arg)|single nucleotide variant|Pathogenic|KRAS|criteria provided, single submitter|12","12594|NM_033360.4(KRAS):c.15A>T (p.Lys5Asn)|single nucleotide variant|Pathogenic|KRAS|reviewed by expert panel|12","12595|NM_033360.4(KRAS):c.*22C>G|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12596|NM_004985.5(KRAS):c.13A>G (p.Lys5Glu)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","12597|NM_033360.4(KRAS):c.178G>A (p.Gly60Ser)|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","1263524|NM_033360.4(KRAS):c.290+97A>C|single nucleotide variant|Benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1264725|NM_004985.5(KRAS):c.453T>C (p.Gly151=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1267974|NM_004985.5(KRAS):c.450+304_450+322del|Deletion|Benign|KRAS|criteria provided, single submitter|12","1270772|NM_004985.5(KRAS):c.-12+162G>C|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","1276764|NM_004985.5(KRAS):c.450+298T>A|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","1279239|NM_033360.4(KRAS):c.290+97A>T|single nucleotide variant|Benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1292363|NM_004985.5(KRAS):c.291-162A>C|single nucleotide variant|Benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1294373|NM_004985.5(KRAS):c.111+190A>T|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","1298542|NM_004985.5(KRAS):c.516A>C (p.Lys172Asn)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1318518|NM_004985.5(KRAS):c.250A>G (p.Ile84Val)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, multiple submitters, no conflicts|12","1327505|NM_004985.5(KRAS):c.445A>T (p.Arg149Ter)|single nucleotide variant|Likely pathogenic|KRAS|no assertion criteria provided|12","132969|NM_033360.4(KRAS):c.176C>T (p.Ala59Val)|single nucleotide variant|not provided|KRAS|no classification provided|12","132970|NM_033360.4(KRAS):c.216G>A (p.Met72Ile)|single nucleotide variant|not provided|KRAS|no classification provided|12","132971|NM_033360.4(KRAS):c.219G>A (p.Arg73=)|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1333392|NM_004985.5(KRAS):c.76A>C (p.Asn26His)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1334243|NM_004985.5(KRAS):c.-14G>C|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1334244|NM_004985.5(KRAS):c.-167_-153dup|Duplication|Uncertain significance|KRAS|criteria provided, single submitter|12","1372540|NM_004985.5(KRAS):c.482G>A (p.Arg161Gln)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","138060|NM_004985.5(KRAS):c.451-14T>C|single nucleotide variant|Likely benign|KRAS|reviewed by expert panel|12","138061|NM_033360.4(KRAS):c.90C>T (p.Asp30=)|single nucleotide variant|Likely benign|KRAS|reviewed by expert panel|12","138062|NM_004985.5(KRAS):c.-48G>A|single nucleotide variant|Benign/Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","138063|NM_004985.5(KRAS):c.-27C>T|single nucleotide variant|Benign/Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1411309|NC_000012.11:g.(?_25362729)_(25398318_?)del|Deletion|Uncertain significance|KRAS|criteria provided, single submitter|12","1419488|NM_004985.5(KRAS):c.536A>G (p.Lys179Arg)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1433063|NC_000012.11:g.(?_25362729)_(25398318_?)dup|Duplication|Uncertain significance|KRAS|criteria provided, single submitter|12","1512544|NM_004985.5(KRAS):c.332T>C (p.Met111Thr)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1518585|NM_004985.5(KRAS):c.324T>G (p.Asp108Glu)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","1531075|NM_004985.5(KRAS):c.186G>A (p.Glu62=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","155804|NM_004985.5(KRAS):c.528GAA[3] (p.Lys180dup)|Microsatellite|Uncertain significance|KRAS|no assertion criteria provided|12","156338|NM_033360.4(KRAS):c.347A>G (p.Asn116Ser)|single nucleotide variant|Likely pathogenic|KRAS|criteria provided, single submitter|12","1574667|NM_004985.5(KRAS):c.372A>G (p.Thr124=)|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1592419|NM_004985.5(KRAS):c.290+18A>G|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1623396|NM_004985.5(KRAS):c.60G>A (p.Thr20=)|single nucleotide variant|Likely benign|KRAS|criteria provided, multiple submitters, no conflicts|12","1627868|NM_004985.5(KRAS):c.291-18C>T|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","1637064|NM_004985.5(KRAS):c.112-14T>G|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12","163758|NM_004985.5(KRAS):c.466T>A (p.Phe156Ile)|single nucleotide variant|Pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","163759|NM_004985.5(KRAS):c.451-5617A>G|single nucleotide variant|Benign|KRAS|criteria provided, single submitter|12","163761|NM_004985.5(KRAS):c.290G>A (p.Arg97Lys)|single nucleotide variant|Likely pathogenic|KRAS|no assertion criteria provided|12","163762|NM_004985.5(KRAS):c.228G>A (p.Glu76=)|single nucleotide variant|Uncertain significance|KRAS|criteria provided, single submitter|12","163766|NM_004985.5(KRAS):c.179G>T (p.Gly60Val)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","163768|NM_004985.5(KRAS):c.108A>G (p.Ile36Met)|single nucleotide variant|Pathogenic/Likely pathogenic|KRAS|criteria provided, multiple submitters, no conflicts|12","163769|NM_004985.5(KRAS):c.39C>A (p.Gly13=)|single nucleotide variant|Likely pathogenic|KRAS|criteria provided, single submitter|12","163771|NM_004985.5(KRAS):c.-160A>G|single nucleotide variant|Benign|KRAS|reviewed by expert panel|12","163772|NM_004985.5(KRAS):c.-167A>G|single nucleotide variant|Likely benign|KRAS|criteria provided, single submitter|12"]}]}