{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:6973,10,HGNC:6973,32,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:6973","source":"HGNC:6973|MDM2 proto-oncogene","targets":["1000905|NM_002392.6(MDM2):c.583A>G (p.Ile195Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1019954|NM_002392.6(MDM2):c.1232A>G (p.Tyr411Cys)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1025823|NM_002392.6(MDM2):c.560G>C (p.Arg187Thr)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1046432|NM_002392.6(MDM2):c.350A>G (p.Asn117Ser)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1058916|NM_002392.6(MDM2):c.1121A>G (p.Asn374Ser)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1086738|NM_002392.6(MDM2):c.264A>G (p.Leu88=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1108186|NM_002392.6(MDM2):c.450A>G (p.Glu150=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1120599|NM_002392.6(MDM2):c.777T>C (p.Ser259=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1124507|NM_002392.6(MDM2):c.960C>G (p.Pro320=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1135955|NM_002392.6(MDM2):c.1002T>C (p.Asn334=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1139277|NM_002392.6(MDM2):c.366G>A (p.Ser122=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1141905|NM_002392.6(MDM2):c.724T>C (p.Leu242=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1152939|NM_002392.6(MDM2):c.175-7A>G|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1154571|NM_002392.6(MDM2):c.447G>A (p.Gln149=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1164285|NC_000012.12:g.68808017C>G|single nucleotide variant|Benign|MDM2|criteria provided, single submitter|12","1164286|NM_002392.6(MDM2):c.-94A>G|single nucleotide variant|Benign|MDM2|criteria provided, multiple submitters, no conflicts|12","1167676|NM_002392.6(MDM2):c.1080A>G (p.Glu360=)|single nucleotide variant|Benign|MDM2|criteria provided, multiple submitters, no conflicts|12","1168231|NM_002392.6(MDM2):c.14+285G>C|single nucleotide variant|Benign|MDM2|criteria provided, single submitter|12","1368535|NM_002392.6(MDM2):c.1242A>C (p.Gln414His)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1371263|NM_002392.6(MDM2):c.698_700del (p.Gly233del)|Deletion|Uncertain significance|MDM2|criteria provided, single submitter|12","1374091|NC_000012.11:g.(?_69202258)_(69233629_?)dup|Duplication|Uncertain significance|MDM2|criteria provided, single submitter|12","1378191|NM_002392.6(MDM2):c.1002T>A (p.Asn334Lys)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1384380|NM_002392.6(MDM2):c.185A>T (p.Tyr62Phe)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1386125|NM_002392.6(MDM2):c.523+5A>G|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1389831|NM_002392.6(MDM2):c.971A>T (p.His324Leu)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1407040|NM_002392.6(MDM2):c.154G>C (p.Asp52His)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1407903|NM_002392.6(MDM2):c.1039A>G (p.Ile347Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1416821|NM_002392.6(MDM2):c.226A>C (p.Lys76Gln)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1431908|NM_002392.6(MDM2):c.365C>T (p.Ser122Leu)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1437659|NM_002392.6(MDM2):c.948A>C (p.Glu316Asp)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1437694|NM_002392.6(MDM2):c.1219A>G (p.Ser407Gly)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1448253|NM_002392.6(MDM2):c.1289A>T (p.Glu430Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1466586|NM_002392.6(MDM2):c.913T>G (p.Leu305Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1471228|NM_002392.6(MDM2):c.886T>G (p.Ser296Ala)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1482898|NM_002392.6(MDM2):c.536A>G (p.Asp179Gly)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1501438|NM_002392.6(MDM2):c.212G>A (p.Arg71Gln)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1504296|NM_002392.6(MDM2):c.818A>C (p.Glu273Ala)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","1507206|NM_002392.6(MDM2):c.1237A>G (p.Ser413Gly)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1551851|NM_002392.6(MDM2):c.175-13A>G|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1569761|NM_002392.6(MDM2):c.1365C>T (p.Cys455=)|single nucleotide variant|Likely benign|MDM2|criteria provided, multiple submitters, no conflicts|12","1570222|NM_002392.6(MDM2):c.309-5A>C|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1570835|NM_002392.6(MDM2):c.524-8A>G|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1584716|NM_002392.6(MDM2):c.162T>C (p.Tyr54=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1596961|NM_002392.6(MDM2):c.816A>G (p.Gln272=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1597128|NM_002392.6(MDM2):c.359-15T>C|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1599971|NM_002392.6(MDM2):c.918+15A>T|single nucleotide variant|Benign|MDM2|criteria provided, single submitter|12","1624296|NM_002392.6(MDM2):c.919-11T>C|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1631003|NM_002392.6(MDM2):c.243A>G (p.Val81=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1635742|NM_002392.6(MDM2):c.1491C>T (p.Pro497=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1674900|NM_002392.6(MDM2):c.840+14del|Deletion|Benign|MDM2|criteria provided, single submitter|12","1916784|NM_002392.6(MDM2):c.393C>T (p.Asn131=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1917952|NM_002392.6(MDM2):c.684+20T>C|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","1924439|NM_002392.6(MDM2):c.174+18A>G|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1930017|NM_002392.6(MDM2):c.589C>T (p.Leu197Phe)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1934140|NM_002392.6(MDM2):c.1114A>G (p.Ile372Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1938361|NM_002392.6(MDM2):c.398G>A (p.Cys133Tyr)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1961369|NM_002392.6(MDM2):c.1301C>G (p.Ser434Cys)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","1993941|NM_002392.6(MDM2):c.1079A>G (p.Glu360Gly)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2015499|NM_002392.6(MDM2):c.1030A>G (p.Lys344Glu)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2032377|NM_002392.6(MDM2):c.841-16G>T|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2037810|NM_002392.6(MDM2):c.359-4T>G|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2041198|NM_002392.6(MDM2):c.175-15A>T|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2047388|NM_002392.6(MDM2):c.403C>T (p.Leu135Phe)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2052780|NM_002392.6(MDM2):c.359-8TC[2]|Microsatellite|Likely benign|MDM2|criteria provided, single submitter|12","2055577|NM_002392.6(MDM2):c.1304G>A (p.Ser435Asn)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2062095|NM_002392.6(MDM2):c.840+6dup|Duplication|Likely benign|MDM2|criteria provided, single submitter|12","2067239|NM_002392.6(MDM2):c.643A>G (p.Arg215Gly)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2067479|NM_002392.6(MDM2):c.1191T>G (p.Ser397Arg)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2075508|NM_002392.6(MDM2):c.372A>G (p.Ser124=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2088438|NM_002392.6(MDM2):c.385A>C (p.Ser129Arg)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2109271|NM_002392.6(MDM2):c.1011T>A (p.Pro337=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2123088|NM_002392.6(MDM2):c.305A>G (p.His102Arg)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2141608|NM_002392.6(MDM2):c.684+19G>A|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2143363|NM_002392.6(MDM2):c.1202C>T (p.Ser401Phe)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2156229|NM_002392.6(MDM2):c.1248T>C (p.Asp416=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2163429|NM_002392.6(MDM2):c.234A>G (p.Gln78=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2164923|NM_002392.6(MDM2):c.613C>G (p.Leu205Val)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2165333|NM_002392.6(MDM2):c.431T>C (p.Leu144Pro)|single nucleotide variant|Conflicting classifications of pathogenicity|MDM2|criteria provided, conflicting classifications|12","2168876|NM_002392.6(MDM2):c.615G>C (p.Leu205=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2170024|NM_002392.6(MDM2):c.1161A>C (p.Lys387Asn)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2179863|NM_002392.6(MDM2):c.421C>G (p.Gln141Glu)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2181570|NM_002392.6(MDM2):c.694G>T (p.Ala232Ser)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2185408|NM_002392.6(MDM2):c.910T>C (p.Ser304Pro)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2194542|NM_002392.6(MDM2):c.1190G>A (p.Ser397Asn)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","2316871|NM_002392.6(MDM2):c.919G>A (p.Asp307Asn)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2415997|NM_002392.6(MDM2):c.999G>T (p.Glu333Asp)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2707346|NM_002392.6(MDM2):c.792T>C (p.Asp264=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2712337|NM_002392.6(MDM2):c.864G>A (p.Gln288=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2713641|NM_002392.6(MDM2):c.1150A>T (p.Asn384Tyr)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2717686|NM_002392.6(MDM2):c.685-20A>T|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2717687|NM_002392.6(MDM2):c.685-18A>T|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2720273|NM_002392.6(MDM2):c.377C>T (p.Thr126Ile)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2721952|NM_002392.6(MDM2):c.1405A>T (p.Thr469Ser)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, multiple submitters, no conflicts|12","2723519|NM_002392.6(MDM2):c.1309C>T (p.Pro437Ser)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2727921|NM_002392.6(MDM2):c.1485T>C (p.Tyr495=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2733057|NM_002392.6(MDM2):c.156C>T (p.Asp52=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2733344|NM_002392.6(MDM2):c.992T>G (p.Leu331Arg)|single nucleotide variant|Uncertain significance|MDM2|criteria provided, single submitter|12","2754667|NM_002392.6(MDM2):c.858G>T (p.Val286=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2776101|NM_002392.6(MDM2):c.783C>T (p.Asp261=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12","2789656|NM_002392.6(MDM2):c.672G>A (p.Thr224=)|single nucleotide variant|Likely benign|MDM2|criteria provided, single submitter|12"]}]}