{"context":{"query":">>hgnc>>msigdb","source_dataset":"hgnc","target_dataset":"msigdb"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:7551,10,HGNC:7551,129,1]["},"schema":"id|standard_name|collection|description|gene_count","mappings":[{"input":"HGNC:7551","source":"HGNC:7551|myosin binding protein C3","targets":["M10039|GOBP_CARDIAC_CHAMBER_DEVELOPMENT|C5:GO|The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. [GOC:mtg_heart]|177","M10277|MULLIGHAN_NPM1_SIGNATURE_3_UP|C2|The 'NPM1 signature 3': genes up-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297].|335","M10365|GOBP_MUSCLE_TISSUE_DEVELOPMENT|C5:GO|The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. [GOC:dph]|454","M10531|GOBP_CIRCULATORY_SYSTEM_PROCESS|C5:GO|An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. [GOC:mtg_cardio]|645","M10631|GOBP_CARDIAC_CHAMBER_MORPHOGENESIS|C5:GO|The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. [GOC:mtg_heart]|135","M11022|MAZ_Q6|C3:TFT|Genes having at least one occurrence of the motif GGGGAGGG in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the MAZ [GeneSymbol=MAZ] transcription factor binding site V$MAZ_Q6 (v7.4 TRANSFAC).|193","M11028|ROVERSI_GLIOMA_COPY_NUMBER_UP|C2|Genes in the most frequently gained loci in a panel of glioma cell lines.|100","M11134|GOBP_STRIATED_MUSCLE_CELL_DIFFERENTIATION|C5:GO|The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. [CL:0000737, GOC:ai]|321","M11569|GOBP_SARCOMERE_ORGANIZATION|C5:GO|The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. [GOC:bf]|50","M11742|GNF2_MYL3|C4|Neighborhood of MYL3|31","M11956|GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS|C5:GO|Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. [GOC:mah]|401","M12144|BROWNE_HCMV_INFECTION_48HR_DN|C2|Genes down-regulated in primary fibroblast cell culture after infection with HCMV (AD169 strain) at 48 h time point that were not down-regulated at the previous time point, 24 h.|481","M12174|GOBP_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION|C5:GO|Any process that modulates the frequency, rate or extent of striated muscle contraction. [GOC:go_curators]|105","M12326|GOBP_ANIMAL_ORGAN_MORPHOGENESIS|C5:GO|Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. [GOC:dgh, GOC:go_curators, ISBN:0471245208, ISBN:0721662544]|1038","M12506|GOBP_REGULATION_OF_MUSCLE_CONTRACTION|C5:GO|Any process that modulates the frequency, rate or extent of muscle contraction. [GOC:go_curators]|179","M12538|GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT|C5:GO|The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. [GOC:mtg_heart]|62","M12564|GOBP_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS|C5:GO|The cellular component assembly that is part of the initial shaping of the component during its developmental progression. [GOC:dph, GOC:tb]|136","M12572|GOBP_MUSCLE_STRUCTURE_DEVELOPMENT|C5:GO|The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. [GOC:dph]|731","M12628|GOBP_MUSCLE_CONTRACTION|C5:GO|A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. [GOC:ef, GOC:mtg_muscle, ISBN:0198506732]|368","M12997|GOBP_HEART_MORPHOGENESIS|C5:GO|The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:dph, GOC:isa_complete]|278","M13052|GATA6_01|C3:TFT|Genes having at least one occurrence of the motif NNNGATWANN in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the GATA6 [GeneSymbol=GATA6] transcription factor binding site V$GATA6_01 (v7.4 TRANSFAC).|269","M13054|GOBP_REGULATION_OF_CELLULAR_LOCALIZATION|C5:GO|Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. [GOC:dph, GOC:tb]|1040","M13090|GOBP_CARDIAC_VENTRICLE_MORPHOGENESIS|C5:GO|The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. [GOC:mtg_heart]|74","M13335|GOBP_ACTOMYOSIN_STRUCTURE_ORGANIZATION|C5:GO|A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. [GOC:dph, GOC:jl, GOC:mah]|216","M13376|GOBP_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS|C5:GO|The process in which the anatomical structures of cardiac muscle tissue are generated and organized. [GOC:devbiol]|62","M13393|GOBP_MUSCLE_ORGAN_MORPHOGENESIS|C5:GO|The process in which the anatomical structures of muscle are generated and organized. [GOC:jid]|86","M13694|GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION|C5:GO|The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell. [GOC:BHF, GOC:mtg_cardiac_conduct_nov11]|91","M13708|GOBP_ORGANELLE_ASSEMBLY|C5:GO|The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. [GOC:mah]|1083","M13718|GOBP_CARDIAC_VENTRICLE_DEVELOPMENT|C5:GO|The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. [GOC:mtg_heart]|134","M14012|GATA1_04|C3:TFT|Genes having at least one occurrence of the motif NNCWGATARNNNN in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the GATA1 [GeneSymbol=GATA1] transcription factor binding site V$GATA1_04 (v7.4 TRANSFAC).|247","M14073|GOBP_ACTIN_MEDIATED_CELL_CONTRACTION|C5:GO|The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body. [GOC:mah]|123","M14186|GATA1_03|C3:TFT|Genes having at least one occurrence of the motif ANGNDGATAANNGN in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the GATA1 [GeneSymbol=GATA1] transcription factor binding site V$GATA1_03 (v7.4 TRANSFAC).|246","M14237|GOBP_REGULATION_OF_SYSTEM_PROCESS|C5:GO|Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. [GOC:jl]|594","M14799|GOMF_ACTIN_BINDING|C5:GO|Binding to monomeric or multimeric forms of actin, including actin filaments. [GOC:clt]|447","M14929|GOBP_HEART_PROCESS|C5:GO|A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:mtg_cardio]|275","M14930|GOBP_MUSCLE_SYSTEM_PROCESS|C5:GO|An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. [GOC:mtg_cardio]|479","M15145|GOMF_STRUCTURAL_CONSTITUENT_OF_MUSCLE|C5:GO|The action of a molecule that contributes to the structural integrity of a muscle fiber. [GOC:mah]|43","M15281|GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT|C5:GO|Any process that modulates the frequency, rate or extent of actin filament-based movement. [GO_REF:0000058, GOC:TermGenie, PMID:24798735]|43","M15630|GOBP_REGULATION_OF_TRANSPORT|C5:GO|Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]|1663","M15697|GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION|C5:GO|Any process that modulates the frequency, rate or extent of cardiac muscle contraction. [GOC:ecd]|86","M15722|GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS|C5:GO|Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. [GOC:dph, GOC:tb]|262","M16103|GOBP_TISSUE_MORPHOGENESIS|C5:GO|The process in which the anatomical structures of a tissue are generated and organized. [GOC:dph, GOC:jid]|638","M16122|GOBP_MUSCLE_CELL_DEVELOPMENT|C5:GO|The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. [CL:0000187, GOC:devbiol]|206","M16149|GOBP_REGULATION_OF_INTRACELLULAR_TRANSPORT|C5:GO|Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. [GOC:mah]|274","M16442|GOBP_CIRCULATORY_SYSTEM_DEVELOPMENT|C5:GO|The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. [GOC:mah, UBERON:0001009]|1268","M16818|GOBP_REGULATION_OF_BLOOD_CIRCULATION|C5:GO|Any process that modulates the frequency, rate or extent of blood circulation. [GO_REF:0000058, GOC:mr, GOC:TermGenie, PMID:10659969]|279","M17000|CP2_01|C3:TFT|Genes having at least one occurrence of the motif GCHCDAMCCAG in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the TFCP2 [GeneSymbol=TFCP2] transcription factor binding site V$CP2_01 (v7.4 TRANSFAC).|261","M17139|GOCC_MYOFILAMENT|C5:GO|Any of the smallest contractile units of a myofibril (striated muscle fiber). [Wikipedia:Myofilament]|26","M17152|GOBP_MUSCLE_CELL_DIFFERENTIATION|C5:GO|The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. [CL:0000187, GOC:go_curators]|441","M17208|GOCC_M_BAND|C5:GO|The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines. [GOC:mtg_muscle, ISBN:0198506732, ISBN:0815316194]|29","M17213|GOCC_MYOSIN_FILAMENT|C5:GO|A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament. [GOC:mah]|24","M17675|GOCC_A_BAND|C5:GO|The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line. [ISBN:0321204131]|41","M17820|GOBP_ACTIN_FILAMENT_BASED_MOVEMENT|C5:GO|Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. [GOC:BHF, GOC:mah]|146","M18050|GOMF_ATPASE_ACTIVATOR_ACTIVITY|C5:GO|Binds to and increases the activity of an ATP hydrolysis activity. [GOC:ajp]|27","M18130|GOMF_ATPASE_REGULATOR_ACTIVITY|C5:GO|Binds to and modulates the activity of an ATP hydrolysis activity. [GOC:dph, GOC:tb]|50","M18503|GOMF_CYTOSKELETAL_PROTEIN_BINDING|C5:GO|Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). [GOC:mah]|1002","M18560|GOMF_MYOSIN_HEAVY_CHAIN_BINDING|C5:GO|Binding to a heavy chain of a myosin complex. [GOC:mah]|13","M18647|REACTOME_STRIATED_MUSCLE_CONTRACTION|C2:CP|Striated Muscle Contraction|36","M18819|GOMF_TITIN_BINDING|C5:GO|Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively. [GOC:mah, PMID:10481174]|13","M18958|GOMF_MYOSIN_BINDING|C5:GO|Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments. [GOC:mah]|73","M19170|MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP|C2|The 'NPM1-mutated signature 1': genes up-regulated in pediatric AML (acute myeloid leukemia) samples with mutated NPM1 [GeneID=4869] compared to all AML cases with the intact gene.|265","M19177|GOMF_STRUCTURAL_MOLECULE_ACTIVITY|C5:GO|The action of a molecule that contributes to the structural integrity of a complex. [GOC:mah, GOC:vw]|827","M19924|GOBP_STRIATED_MUSCLE_CONTRACTION|C5:GO|A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. [GOC:jl, GOC:mtg_muscle, ISBN:0198506732]|202","M2098|MARTENS_TRETINOIN_RESPONSE_UP|C2|Genes up-regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip-seq data.|854","M23816|GOBP_INTRACELLULAR_TRANSPORT|C5:GO|The directed movement of substances within a cell. [GOC:ai]|1386","M24087|GOBP_CARDIAC_MUSCLE_CONTRACTION|C5:GO|Muscle contraction of cardiac muscle tissue. [GOC:dph]|154","M24772|GOBP_SUPRAMOLECULAR_FIBER_ORGANIZATION|C5:GO|A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. [GOC:pr]|878","M2584|KAAB_HEART_ATRIUM_VS_VENTRICLE_DN|C2|Genes down-regulated in the ventricles of healthy hearts, compared to atria.|261","M25959|GOCC_CARDIAC_MYOFIBRIL|C5:GO|A cardiac myofibril is a myofibril specific to cardiac muscle cells. [GOC:cjm, GOC:devbiol]|7","M26011|GOCC_SUPRAMOLECULAR_COMPLEX|C5:GO|A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. [GOC:dos]|1453","M2693|P53_DN.V2_DN|C6|Genes down-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of TP53 [Gene ID=7157] gene by RNAi.|145","M2696|RELA_DN.V1_UP|C6|Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA [Gene ID=5970] gene by RNAi.|149","M2830|PDGF_ERK_DN.V1_UP|C6|Genes up-regulated in SH-SY5Y cells (neuroblastoma) in response to PDGF [Gene ID=] stimulation after pre-treatment with the ERK inhibitors U0126 and PD98059 [PubChem=3006531, 4713].|145","M29440|GOCC_SUPRAMOLECULAR_POLYMER|C5:GO|A polymeric supramolecular structure. [GOC:dos]|1076","M2958|GATA1_05|C3:TFT|Genes having at least one occurrence of the motif NCWGATAACA in the regions spanning 4 kb centered on their transcription starting sites [-2kb, +2kb].  This matches the GATA1 [GeneSymbol=GATA1] transcription factor binding site V$GATA1_05 (v7.4 TRANSFAC).|285","M30002|HMGA1_TARGET_GENES|C3:TFT|Genes containing one or more binding sites for UniProt:P17096 (HMGA1) in their promoter regions (TSS -1000,+100 bp) as identified by GTRD version 20.06 ChIP-seq harmonization.|1260","M30546|MIR137_3P|C3:MIR|Genes predicted to be targets of miRBase v22 microRNA hsa-miR-137-3p in miRDB v6.0 with MirTarget v4 prediction scores > 80 (high confidence targets).|531","M3060|GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_UP|C7|Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219].|199","M3187|GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP|C7|Genes up-regulated in comparison of IgD+ B cells from peripheral blood versus CD19 pre-germinal center tonsil B cell|199","M3365|GSE14308_TH2_VS_NAIVE_CD4_TCELL_DN|C7|Genes down-regulated in comparison of Th2 cells versus naive CD4 [GeneID=620] T cells.|200","M337|GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP|C7|Genes up-regulated in Sez-2 cells (T cell lymphoma): IL15 [GeneID=3600] versus IL21 [GeneID=3600].|165","M35209|HP_SYNCOPE|C5|Syncope|121","M35220|HP_STROKE|C5|Stroke|190","M35268|HP_ABNORMALITY_OF_THE_LIVER|C5|Abnormality of the liver|1129","M35293|HP_ABNORMAL_ABDOMEN_MORPHOLOGY|C5|Abnormal abdomen morphology|873","M35322|HP_ASCITES|C5|Ascites|137","M35364|HP_CONGESTIVE_HEART_FAILURE|C5|Congestive heart failure|270","M35366|HP_ABNORMAL_MYOCARDIUM_MORPHOLOGY|C5|Abnormal myocardium morphology|609","M35367|HP_HYPERTROPHIC_CARDIOMYOPATHY|C5|Hypertrophic cardiomyopathy|290","M35368|HP_CARDIOMEGALY|C5|Cardiomegaly|136","M35372|HP_DILATED_CARDIOMYOPATHY|C5|Dilated cardiomyopathy|184","M35384|HP_VENTRICULAR_FIBRILLATION|C5|Ventricular fibrillation|56","M35389|HP_ABNORMAL_CARDIAC_SEPTUM_MORPHOLOGY|C5|Abnormal cardiac septum morphology|782","M35400|HP_CARDIAC_ARREST|C5|Cardiac arrest|158","M35401|HP_ABNORMAL_PERICARDIUM_MORPHOLOGY|C5|Abnormal pericardium morphology|83","M35402|HP_PERICARDIAL_EFFUSION|C5|Pericardial effusion|45","M35403|HP_SUDDEN_DEATH|C5|Sudden death|130","M35412|HP_ABNORMAL_CARDIAC_VENTRICLE_MORPHOLOGY|C5|Abnormal cardiac ventricle morphology|728","M35413|HP_VENTRICULAR_HYPERTROPHY|C5|Ventricular hypertrophy|175","M35514|HP_THROMBOEMBOLISM|C5|Thromboembolism|101"]}]}