{"context":{"query":">>hgnc>>clinvar","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:7989,10,HGNC:7989,174,0]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:7989","source":"HGNC:7989|NRAS proto-oncogene, GTPase","targets":["1003866|NM_002524.5(NRAS):c.272C>T (p.Ala91Val)|single nucleotide variant|Uncertain significance|NRAS|reviewed by expert panel|1","1010637|NM_002524.5(NRAS):c.539_*4+1del|Deletion|Uncertain significance|NRAS|criteria provided, single submitter|1","1064816|NM_002524.5(NRAS):c.490C>T (p.Arg164Cys)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1070042|NM_002524.5(NRAS):c.173C>T (p.Thr58Ile)|single nucleotide variant|Pathogenic|NRAS|reviewed by expert panel|1","1090778|NM_002524.5(NRAS):c.531G>A (p.Gly177=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1096606|NM_002524.5(NRAS):c.318G>A (p.Ser106=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1096908|NM_002524.5(NRAS):c.411C>T (p.Tyr137=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1099851|NM_002524.5(NRAS):c.450+7T>C|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1107573|NM_002524.5(NRAS):c.69A>G (p.Leu23=)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1194887|NM_002524.5(NRAS):c.291-315A>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1203810|NM_002524.5(NRAS):c.370A>G (p.Thr124Ala)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1212805|NM_002524.5(NRAS):c.-17-4A>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1220450|NM_002524.5(NRAS):c.74A>G (p.Gln25Arg)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1231751|NM_002524.5(NRAS):c.112-70C>T|single nucleotide variant|Benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1253391|NM_002524.5(NRAS):c.112-24C>A|single nucleotide variant|Benign|NRAS|criteria provided, single submitter|1","1276759|NM_002524.5(NRAS):c.-18+195C>T|single nucleotide variant|Benign|NRAS|criteria provided, single submitter|1","1284606|NM_002524.5(NRAS):c.450+12C>T|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1301342|NM_002524.5(NRAS):c.290+15A>G|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1307680|NM_002524.5(NRAS):c.542G>T (p.Cys181Phe)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1308381|NM_002524.5(NRAS):c.64C>T (p.Gln22Ter)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1312812|NM_002524.5(NRAS):c.394G>C (p.Glu132Gln)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1313158|NM_002524.5(NRAS):c.554C>T (p.Pro185Leu)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1320040|NM_002524.5(NRAS):c.268T>C (p.Phe90Leu)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1320232|NM_002524.5(NRAS):c.449A>G (p.Gln150Arg)|single nucleotide variant|Likely pathogenic|NRAS|criteria provided, single submitter|1","1334247|NM_002524.5(NRAS):c.179G>T (p.Gly60Val)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1334265|NM_002524.5(NRAS):c.42T>C (p.Val14=)|single nucleotide variant|Conflicting classifications of pathogenicity|NRAS|criteria provided, conflicting classifications|1","1334643|NM_002524.5(NRAS):c.274G>A (p.Asp92Asn)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1335888|NM_002524.5(NRAS):c.108A>G (p.Ile36Met)|single nucleotide variant|Likely pathogenic|NRAS|criteria provided, single submitter|1","1349748|NM_002524.5(NRAS):c.562G>T (p.Val188Leu)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","134991|NM_002524.5(NRAS):c.504G>C (p.Met168Ile)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1353931|NM_002524.5(NRAS):c.478G>A (p.Val160Ile)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1361101|NM_002524.5(NRAS):c.499C>T (p.Arg167Ter)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1379022|NM_002524.5(NRAS):c.22G>A (p.Val8Met)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1380557|NM_002524.5(NRAS):c.140A>G (p.Asp47Gly)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","138538|NM_002524.5(NRAS):c.112-8A>G|single nucleotide variant|Likely benign|NRAS|reviewed by expert panel|1","13899|NM_002524.5(NRAS):c.37G>C (p.Gly13Arg)|single nucleotide variant|Likely pathogenic|NRAS|criteria provided, multiple submitters, no conflicts|1","13900|NM_002524.5(NRAS):c.182A>G (p.Gln61Arg)|single nucleotide variant|Pathogenic|NRAS|criteria provided, multiple submitters, no conflicts|1","13901|NM_002524.5(NRAS):c.38G>A (p.Gly13Asp)|single nucleotide variant|Pathogenic/Likely pathogenic|NRAS|criteria provided, multiple submitters, no conflicts|1","13902|NM_002524.5(NRAS):c.149C>T (p.Thr50Ile)|single nucleotide variant|Pathogenic|NRAS|reviewed by expert panel|1","13903|NM_002524.5(NRAS):c.179G>A (p.Gly60Glu)|single nucleotide variant|Pathogenic|NRAS|reviewed by expert panel|1","1419784|NM_002524.5(NRAS):c.331A>G (p.Met111Val)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1445087|NM_002524.5(NRAS):c.297G>T (p.Gln99His)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1449526|NM_002524.5(NRAS):c.299T>C (p.Ile100Thr)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1466357|NM_002524.5(NRAS):c.300T>G (p.Ile100Met)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1490849|NM_002524.5(NRAS):c.260G>A (p.Ser87Asn)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1540947|NM_002524.5(NRAS):c.112-14C>T|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1548420|NM_002524.5(NRAS):c.451-12T>C|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1555925|NM_002524.5(NRAS):c.111+18C>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1582033|NM_002524.5(NRAS):c.273G>A (p.Ala91=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1582458|NM_002524.5(NRAS):c.465T>G (p.Ala155=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1583384|NM_002524.5(NRAS):c.451-11T>C|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1611261|NM_002524.5(NRAS):c.111+10A>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1618175|NM_002524.5(NRAS):c.451-14T>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1618918|NM_002524.5(NRAS):c.451-10C>T|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","164807|NM_002524.5(NRAS):c.159G>A (p.Leu53=)|single nucleotide variant|Benign|NRAS|reviewed by expert panel|1","164809|NM_002524.5(NRAS):c.368G>A (p.Arg123Lys)|single nucleotide variant|Uncertain significance|NRAS|reviewed by expert panel|1","1666539|NM_002524.5(NRAS):c.451-17A>G|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1708361|NM_002524.5(NRAS):c.412G>A (p.Gly138Arg)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1714146|NM_002524.5(NRAS):c.430A>G (p.Thr144Ala)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1719074|NM_002524.5(NRAS):c.454G>T (p.Val152Phe)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1723142|NM_002524.5(NRAS):c.180A>G (p.Gly60=)|single nucleotide variant|Uncertain significance|NRAS|no assertion criteria provided|1","1723143|NM_002524.5(NRAS):c.164T>C (p.Ile55Thr)|single nucleotide variant|Uncertain significance|NRAS|no assertion criteria provided|1","1735495|NM_002524.5(NRAS):c.384A>G (p.Lys128=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1748857|NM_002524.5(NRAS):c.564G>C (p.Val188=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1777654|NM_002524.5(NRAS):c.166C>T (p.Leu56=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","177778|NM_002524.5(NRAS):c.34G>A (p.Gly12Ser)|single nucleotide variant|Pathogenic|NRAS|reviewed by expert panel|1","178104|NM_002524.5(NRAS):c.225C>T (p.Gly75=)|single nucleotide variant|Benign/Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1786150|NM_002524.5(NRAS):c.107T>C (p.Ile36Thr)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","1787607|NM_002524.5(NRAS):c.21G>A (p.Val7=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1788063|NM_002524.5(NRAS):c.222A>G (p.Thr74=)|single nucleotide variant|Benign/Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","1789066|NM_002524.5(NRAS):c.228A>G (p.Glu76=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","179025|NM_002524.5(NRAS):c.553C>T (p.Pro185Ser)|single nucleotide variant|Uncertain significance|NRAS|reviewed by expert panel|1","1792664|NM_002524.5(NRAS):c.252C>T (p.Ile84=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1803496|NM_002524.5(NRAS):c.304C>T (p.Arg102Ter)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","180717|NM_002524.5(NRAS):c.562G>A (p.Val188Met)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","181461|NM_002524.5(NRAS):c.442A>G (p.Thr148Ala)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1907174|NM_002524.5(NRAS):c.450+6G>A|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","1937169|NM_002524.5(NRAS):c.524ATG[3] (p.Asp176_Gly177insAsp)|Microsatellite|Uncertain significance|NRAS|criteria provided, single submitter|1","1945834|NM_002524.5(NRAS):c.112-14del|Deletion|Likely benign|NRAS|criteria provided, single submitter|1","1985945|NM_002524.5(NRAS):c.519C>T (p.Ser173=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","1987126|NM_002524.5(NRAS):c.425T>C (p.Ile142Thr)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2000338|NM_002524.5(NRAS):c.441G>T (p.Lys147Asn)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2020829|NM_002524.5(NRAS):c.66G>A (p.Gln22=)|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","2041687|NM_002524.5(NRAS):c.84T>C (p.Phe28=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","2054868|NM_002524.5(NRAS):c.259A>T (p.Ser87Cys)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","2059335|NM_002524.5(NRAS):c.290+4C>T|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2074072|NM_002524.5(NRAS):c.450G>C (p.Gln150His)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2089336|NM_002524.5(NRAS):c.291-14A>T|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","2113743|NM_002524.5(NRAS):c.4A>G (p.Thr2Ala)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","211686|NM_002524.5(NRAS):c.317C>T (p.Ser106Leu)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","2131100|NM_002524.5(NRAS):c.544A>T (p.Met182Leu)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2140266|NM_002524.5(NRAS):c.330T>C (p.Pro110=)|single nucleotide variant|Likely benign|NRAS|criteria provided, multiple submitters, no conflicts|1","2146548|NM_002524.5(NRAS):c.325G>A (p.Val109Ile)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2153924|NM_002524.5(NRAS):c.111+14G>T|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","2158031|NM_002524.5(NRAS):c.291-11C>A|single nucleotide variant|Likely benign|NRAS|criteria provided, single submitter|1","2176086|NM_002524.5(NRAS):c.18GGT[2] (p.Val9del)|Microsatellite|Uncertain significance|NRAS|criteria provided, single submitter|1","2180866|NM_002524.5(NRAS):c.41T>G (p.Val14Gly)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","2185908|NM_002524.5(NRAS):c.305G>A (p.Arg102Gln)|single nucleotide variant|Uncertain significance|NRAS|criteria provided, multiple submitters, no conflicts|1","2189829|NM_002524.5(NRAS):c.450+6G>T|single nucleotide variant|Uncertain significance|NRAS|criteria provided, single submitter|1","219097|NM_002524.5(NRAS):c.35G>C (p.Gly12Ala)|single nucleotide variant|Pathogenic/Likely pathogenic|NRAS|criteria provided, multiple submitters, no conflicts|1"]}]}