{"context":{"query":">>hgnc>>clinvar[germline_classification==\"Uncertain significance\"]","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:9884,10,HGNC:9884,56,1]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:9884","source":"HGNC:9884|RB transcriptional corepressor 1","targets":["1001246|NM_000321.3(RB1):c.45_53dup (p.Ala16_Ala18dup)|Duplication|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1001653|NM_000321.3(RB1):c.586A>G (p.Ile196Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1002084|NM_000321.3(RB1):c.748C>T (p.Pro250Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1002180|NM_000321.3(RB1):c.1903G>T (p.Ala635Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1002901|NM_000321.3(RB1):c.1745C>G (p.Pro582Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1003209|NM_000321.3(RB1):c.1997G>T (p.Cys666Phe)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1003344|NM_000321.3(RB1):c.393C>A (p.Phe131Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1003367|NM_000321.3(RB1):c.265G>A (p.Gly89Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1003580|NM_000321.3(RB1):c.2377C>T (p.Pro793Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1004456|NM_000321.3(RB1):c.1838C>T (p.Pro613Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1004691|NM_000321.3(RB1):c.2450A>G (p.Glu817Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1004720|NM_000321.3(RB1):c.1451T>C (p.Met484Thr)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1004878|NM_000321.3(RB1):c.2518G>T (p.Gly840Trp)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1006053|NM_000321.3(RB1):c.739A>G (p.Asn247Asp)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1006184|NM_000321.3(RB1):c.323T>C (p.Val108Ala)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1006348|NM_000321.3(RB1):c.560C>G (p.Ser187Cys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1008029|NM_000321.3(RB1):c.1685C>T (p.Ala562Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","100809|NM_000321.3(RB1):c.1994T>G (p.Leu665Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1008205|NM_000321.3(RB1):c.1253G>A (p.Arg418Lys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1008260|NM_000321.3(RB1):c.1241G>A (p.Ser414Asn)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1008617|NM_000321.3(RB1):c.98C>G (p.Pro33Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1009471|NM_000321.3(RB1):c.984T>A (p.Asn328Lys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1009646|NM_000321.3(RB1):c.163C>T (p.Pro55Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1010326|NC_000013.10:g.(?_49027115)_(49054207_?)dup|Duplication|Uncertain significance|RB1|criteria provided, single submitter|13","1010518|NM_000321.3(RB1):c.2598C>A (p.Ser866Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1010579|NM_000321.3(RB1):c.121G>A (p.Asp41Asn)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1010949|NM_000321.3(RB1):c.1126A>G (p.Arg376Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1011124|NM_000321.3(RB1):c.2475G>A (p.Met825Ile)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1014111|NM_000321.3(RB1):c.1465T>G (p.Cys489Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1014135|NM_000321.3(RB1):c.1022A>G (p.Lys341Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1015277|NM_000321.3(RB1):c.860A>G (p.Glu287Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1015555|NM_000321.3(RB1):c.2735A>G (p.Gln912Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016018|NM_000321.3(RB1):c.479C>T (p.Ala160Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016303|NM_000321.3(RB1):c.891A>G (p.Ile297Met)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016393|NM_000321.3(RB1):c.2726C>T (p.Thr909Ile)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016796|NM_000321.3(RB1):c.2612C>T (p.Pro871Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016810|NM_000321.3(RB1):c.1163_1168dup (p.Ile388_Leu389dup)|Duplication|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1016834|NM_000321.3(RB1):c.2774A>C (p.Lys925Thr)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1017382|NM_000321.3(RB1):c.1115A>T (p.His372Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1018131|NM_000321.3(RB1):c.26C>T (p.Thr9Met)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1019187|NM_000321.3(RB1):c.2760G>A (p.Met920Ile)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1019424|NC_000013.10:g.(?_48921946)_(48922009_?)del|Deletion|Uncertain significance|RB1|criteria provided, single submitter|13","1019470|NM_000321.3(RB1):c.220G>A (p.Ala74Thr)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1019930|NM_000321.3(RB1):c.688T>G (p.Ser230Ala)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1020043|NM_000321.3(RB1):c.719-2A>C|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1020960|NM_000321.3(RB1):c.2359C>G (p.Arg787Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1021284|NM_000321.3(RB1):c.1731G>C (p.Lys577Asn)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1021709|NM_000321.3(RB1):c.2365C>T (p.Pro789Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1022477|NM_000321.3(RB1):c.2030A>G (p.Glu677Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1022555|NM_000321.3(RB1):c.1769G>T (p.Cys590Phe)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1022893|NM_000321.3(RB1):c.2479C>G (p.Pro827Ala)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1024162|NM_000321.3(RB1):c.1532A>G (p.Asp511Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1024341|NM_000321.3(RB1):c.506G>C (p.Cys169Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1024547|NM_000321.3(RB1):c.2586T>G (p.Ser862Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1025503|NM_000321.3(RB1):c.1123G>C (p.Val375Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1026035|NM_000321.3(RB1):c.2069A>G (p.Asn690Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1026177|NM_000321.3(RB1):c.2244G>C (p.Glu748Asp)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1027088|NM_000321.3(RB1):c.196A>G (p.Ile66Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1027153|NM_000321.3(RB1):c.477T>A (p.Phe159Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1035952|NM_000321.3(RB1):c.1017T>A (p.His339Gln)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1036067|NM_000321.3(RB1):c.1127G>A (p.Arg376Lys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1036703|NM_000321.3(RB1):c.1606A>G (p.Ile536Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1036746|NM_000321.3(RB1):c.364A>G (p.Lys122Glu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1037070|NM_000321.3(RB1):c.727G>C (p.Val243Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1037503|NM_000321.3(RB1):c.749C>G (p.Pro250Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1037634|NM_000321.3(RB1):c.71C>T (p.Pro24Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1038511|NM_000321.3(RB1):c.644C>T (p.Ser215Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1039486|NM_000321.3(RB1):c.691C>T (p.Pro231Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1039739|NM_000321.3(RB1):c.707A>G (p.Lys236Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1039752|NM_000321.3(RB1):c.1964A>T (p.Tyr655Phe)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1039846|NM_000321.3(RB1):c.155C>G (p.Thr52Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1039953|NM_000321.3(RB1):c.548C>T (p.Thr183Ile)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1041083|NM_000321.3(RB1):c.2491A>C (p.Ile831Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1041346|NM_000321.3(RB1):c.1406C>A (p.Ser469Tyr)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1041461|NM_000321.3(RB1):c.520T>G (p.Leu174Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1043349|NM_000321.3(RB1):c.699G>A (p.Met233Ile)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1043395|NM_000321.3(RB1):c.94G>C (p.Asp32His)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1044909|NM_000321.3(RB1):c.206A>G (p.His69Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1045725|NM_000321.3(RB1):c.2520G>T (p.Gly840=)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1045807|NM_000321.3(RB1):c.466G>C (p.Asp156His)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1046453|NM_000321.3(RB1):c.541A>G (p.Ile181Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1046695|NM_000321.3(RB1):c.1828G>T (p.Val610Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1046944|NM_000321.3(RB1):c.2020C>T (p.Pro674Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1047091|NM_000321.3(RB1):c.26C>G (p.Thr9Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1047186|NM_000321.3(RB1):c.2449G>C (p.Glu817Gln)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1047593|NM_000321.3(RB1):c.199C>T (p.Pro67Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1050761|NM_000321.3(RB1):c.2239GAG[1] (p.Glu748del)|Microsatellite|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1051248|NM_000321.3(RB1):c.121G>C (p.Asp41His)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1051249|NM_000321.3(RB1):c.380+5A>T|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1051272|NM_000321.3(RB1):c.1783C>T (p.Pro595Ser)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1052305|NM_000321.3(RB1):c.424A>G (p.Thr142Ala)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1052825|NM_000321.3(RB1):c.2134T>G (p.Cys712Gly)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1052951|NM_000321.3(RB1):c.1205C>G (p.Ser402Cys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1053679|NM_000321.3(RB1):c.2590G>A (p.Glu864Lys)|single nucleotide variant|Uncertain significance|RB1|criteria provided, single submitter|13","1054100|NM_000321.3(RB1):c.1540T>C (p.Phe514Leu)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1054272|NM_000321.3(RB1):c.130C>G (p.Leu44Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1054298|NM_000321.3(RB1):c.2639A>C (p.Glu880Ala)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1054608|NM_000321.3(RB1):c.1467C>G (p.Cys489Trp)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1055369|NM_000321.3(RB1):c.62C>G (p.Pro21Arg)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13","1056846|NM_000321.3(RB1):c.514A>G (p.Ile172Val)|single nucleotide variant|Uncertain significance|RB1|criteria provided, multiple submitters, no conflicts|13"]}]}