{"context":{"query":">>hgnc>>clinvar[germline_classification==\"Pathogenic\"]","source_dataset":"hgnc","target_dataset":"clinvar"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]HGNC:9967,10,HGNC:9967,93,39]["},"schema":"id|name|type|germline_classification|gene_symbol|review_status|chromosome","mappings":[{"input":"HGNC:9967","source":"HGNC:9967|ret proto-oncogene","targets":["1069637|NM_020975.6(RET):c.318G>A (p.Trp106Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1197458|NM_020975.6(RET):c.2137-1G>A|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1372611|NM_020975.6(RET):c.1826G>C (p.Cys609Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13905|NM_020975.6(RET):c.1852T>G (p.Cys618Gly)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13908|NM_020975.6(RET):c.1900T>G (p.Cys634Gly)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13909|NM_020975.6(RET):c.1901G>A (p.Cys634Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13910|NM_020975.6(RET):c.1901G>C (p.Cys634Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13911|NM_020975.6(RET):c.1901G>T (p.Cys634Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13913|NM_020975.6(RET):c.1833C>G (p.Cys611Trp)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","13914|NM_020975.6(RET):c.1853G>C (p.Cys618Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13915|NM_020975.6(RET):c.1858T>C (p.Cys620Arg)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13916|NM_020975.6(RET):c.1859G>A (p.Cys620Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13918|NM_020975.6(RET):c.1902C>G (p.Cys634Trp)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13925|NM_020975.6(RET):c.538C>T (p.Arg180Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","13928|NM_020975.6(RET):c.1859G>T (p.Cys620Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13929|NM_020975.6(RET):c.1852T>C (p.Cys618Arg)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13930|NM_020975.6(RET):c.1892_1903dup (p.Cys634_Arg635insHisGluLeuCys)|Duplication|Pathogenic|RET|no assertion criteria provided|10","13931|NM_020975.6(RET):c.2304G>C (p.Glu768Asp)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13933|NM_020975.6(RET):c.1826G>A (p.Cys609Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13934|NM_020975.6(RET):c.1860C>G (p.Cys620Trp)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13941|NM_020975.6(RET):c.1586_1594dup (p.Cys531_Gly532insGluGluCys)|Duplication|Pathogenic|RET|no assertion criteria provided|10","13942|NM_020975.6(RET):c.1919C>G (p.Ala640Gly)|single nucleotide variant|Pathogenic|RET|no assertion criteria provided|10","13943|NM_020975.6(RET):c.1859G>C (p.Cys620Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13944|NM_020975.6(RET):c.1825T>C (p.Cys609Arg)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13946|NM_020975.6(RET):c.2410G>T (p.Val804Leu)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13950|NM_020975.6(RET):c.1597G>T (p.Gly533Cys)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","13951|NM_020975.6(RET):c.2671T>G (p.Ser891Ala)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","1403312|NM_020975.6(RET):c.1252C>T (p.Arg418Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1405715|NM_020975.6(RET):c.317G>A (p.Trp106Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1406541|NM_020975.6(RET):c.2427C>A (p.Tyr809Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1452055|NM_020975.6(RET):c.1315C>T (p.Gln439Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","1458805|NM_020975.6(RET):c.1902_1903inv (p.Cys634_Arg635delinsTrpGly)|Inversion|Pathogenic|RET|criteria provided, single submitter|10","1727640|NM_020975.6(RET):c.3100_3101del (p.Ser1034fs)|Microsatellite|Pathogenic|RET|criteria provided, single submitter|10","1741794|NM_020975.6(RET):c.45dup (p.Leu16fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","1746871|NM_020975.6(RET):c.532dup (p.Glu178fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","1754024|NM_020975.6(RET):c.652_653dup (p.Asp219fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","1773874|NM_020975.6(RET):c.1495C>T (p.Gln499Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","1782209|NM_020975.6(RET):c.1899_1900delinsAA (p.Cys634Ser)|Indel|Pathogenic|RET|criteria provided, single submitter|10","1798724|NM_020975.6(RET):c.1010_1017del (p.Glu337fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","1799048|NM_020975.6(RET):c.3031A>T (p.Lys1011Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","194425|NM_020975.6(RET):c.2586_2592del (p.Met862fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","201137|NM_020975.6(RET):c.2846del (p.Gly949fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","201140|NM_020975.6(RET):c.2839del (p.Thr946_Leu947insTer)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","2024200|NM_020975.6(RET):c.1001G>A (p.Trp334Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2025097|NM_020975.6(RET):c.1901_1902delinsTT (p.Cys634Phe)|Indel|Pathogenic|RET|criteria provided, single submitter|10","2044531|NM_020975.6(RET):c.1956_1965delinsACCACTCTACCACAAGTT (p.Ser653fs)|Indel|Pathogenic|RET|criteria provided, single submitter|10","2123266|NM_020975.6(RET):c.1044_1051dup (p.Val351fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","2136858|NM_020975.6(RET):c.1832_1833delinsAT (p.Cys611Tyr)|Indel|Pathogenic|RET|criteria provided, single submitter|10","24897|NM_020975.6(RET):c.1831T>G (p.Cys611Gly)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24898|NM_020975.6(RET):c.1832G>A (p.Cys611Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24899|NM_020975.6(RET):c.1832G>T (p.Cys611Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24901|NM_020975.6(RET):c.1853G>A (p.Cys618Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24902|NM_020975.6(RET):c.1853G>T (p.Cys618Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24905|NM_020975.6(RET):c.1858T>G (p.Cys620Gly)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24908|NM_020975.6(RET):c.1888T>C (p.Cys630Arg)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24909|NM_020975.6(RET):c.1889G>A (p.Cys630Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","24914|NM_020975.6(RET):c.1891G>T (p.Asp631Tyr)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","2584517|NM_020975.6(RET):c.971G>A (p.Trp324Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2587893|NM_020975.6(RET):c.2041C>T (p.Gln681Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2629603|NM_020975.6(RET):c.208C>T (p.Gln70Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2698901|NM_020975.6(RET):c.255G>A (p.Trp85Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2770994|NM_020975.6(RET):c.1698del (p.Asp567fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","2779200|NM_020975.6(RET):c.1899_1900delinsTC (p.Cys634Arg)|Indel|Pathogenic|RET|criteria provided, single submitter|10","280193|NM_020975.6(RET):c.890dup (p.Val298fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","2817143|NM_020975.6(RET):c.1160del (p.Gly387fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","2819743|NM_020975.6(RET):c.1347C>A (p.Cys449Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","2866872|NM_020975.6(RET):c.1091_1104del (p.Ile364fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","290965|NM_020975.6(RET):c.2418C>G (p.Tyr806Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","3076011|NM_020975.6(RET):c.1860C>A (p.Cys620Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","3254419|NM_020975.6(RET):c.1825T>G (p.Cys609Gly)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","3337733|NM_020975.6(RET):c.1740_1741dup (p.Cys581fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","3365564|NM_020975.6(RET):c.1144C>T (p.Gln382Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","3644687|NM_020975.6(RET):c.668_669dup (p.Ser224Ter)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","3652177|NM_020975.6(RET):c.2715C>A (p.Tyr905Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","3661014|NM_020975.6(RET):c.758dup (p.Val254fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","3661947|NM_020975.6(RET):c.1341del (p.Asn448fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","3788357|NM_020975.6(RET):c.2307delinsTCGAGACCTGCTGTCAGAGTTCAACGTGAGCTT (p.Leu779fs)|Indel|Pathogenic|RET|criteria provided, single submitter|10","38284|NM_020975.6(RET):c.1826G>T (p.Cys609Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","38601|NM_020975.6(RET):c.1852T>A (p.Cys618Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","38605|NM_020975.6(RET):c.1900T>A (p.Cys634Ser)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","38611|NM_020975.6(RET):c.2304G>T (p.Glu768Asp)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","38612|NM_020975.6(RET):c.2370G>T (p.Leu790Phe)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","3911304|NM_020975.6(RET):c.1597_1609del (p.Gly533fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","3944686|NM_020975.6(RET):c.840_843dup (p.Val282fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","405536|NM_020975.6(RET):c.2689C>T (p.Arg897Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","4152793|NM_020975.6(RET):c.921_922del (p.Glu309fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","4531443|NM_020975.6(RET):c.754G>T (p.Glu252Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","521303|NM_020975.6(RET):c.1425dup (p.Pro476fs)|Duplication|Pathogenic|RET|criteria provided, single submitter|10","560625|NM_020975.6(RET):c.860G>A (p.Arg287Gln)|single nucleotide variant|Pathogenic|RET|no assertion criteria provided|10","590798|NM_020975.6(RET):c.1280_1281del (p.Val427fs)|Microsatellite|Pathogenic|RET|criteria provided, single submitter|10","599630|NM_020975.6(RET):c.111G>A (p.Trp37Ter)|single nucleotide variant|Pathogenic|RET|no assertion criteria provided|10","599634|NM_020975.6(RET):c.2865dup (p.Pro956fs)|Duplication|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","599635|NM_020975.6(RET):c.3143del (p.Leu1048fs)|Deletion|Pathogenic|RET|no assertion criteria provided|10","642786|NM_020975.6(RET):c.268G>T (p.Glu90Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","657955|NM_020975.6(RET):c.1783G>T (p.Glu595Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","692052|NM_020975.6(RET):c.712G>T (p.Glu238Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, single submitter|10","819313|NM_020975.6(RET):c.1471C>T (p.Gln491Ter)|single nucleotide variant|Pathogenic|RET|criteria provided, multiple submitters, no conflicts|10","932072|NM_020975.6(RET):c.2631del (p.Arg878fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","963299|NM_020975.6(RET):c.936_939del (p.Arg312fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10","969297|NM_020975.6(RET):c.1151del (p.Pro384fs)|Deletion|Pathogenic|RET|criteria provided, single submitter|10"]}]}