{"context":{"query":">>mondo>>clinical_trials","source_dataset":"mondo","target_dataset":"clinical_trials"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]MONDO:0004975,73,MONDO:0004975,197,3]["},"schema":"id|brief_title|overall_status|phase|study_type","mappings":[{"input":"MONDO:0004975","source":"MONDO:0004975|Alzheimer disease","targets":["NCT00009191|The Depression in Alzheimer's Disease Study (DIADS)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00009217|Treatment of Behavioral Symptoms in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00018278|Electrophysiologic Measures of Treatment Response in Alzheimer Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00035204|A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00042172|Treatment for Early Memory Loss|COMPLETED|PHASE4|INTERVENTIONAL","NCT00043849|Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00046358|The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00104442|Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00120874|Memantine and Comprehensive, Individualized Management of Alzheimer's Disease and Caregiver Training|COMPLETED|PHASE4|INTERVENTIONAL","NCT00127114|Amantadine for the Treatment of Behavioral Disturbance in Frontotemporal Dementia (FTD)|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00142324|CALM-AD|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00164970|Can Oral Vitamin B12 and Folate Supplementation Preserve Cognitive Function of Patients With Early Dementia?|COMPLETED|PHASE4|INTERVENTIONAL","NCT00165724|Alzheimer's Disease Long-term Follow-up Study (ALF Study)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00165750|Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients|TERMINATED|PHASE4|INTERVENTIONAL","NCT00177671|Antidepressant Medication Plus Donepezil for Treating Late-life Depression|COMPLETED|PHASE4|INTERVENTIONAL","NCT00202124|Double Blind Study of Trp01 in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00208819|A Comparison of Two Standard Therapies in the Management of Dementia With Agitation|COMPLETED|PHASE4|INTERVENTIONAL","NCT00216515|The Efficacy of Galantamine on the Attention and the Frontal Function of the Patients With Dementia of Alzheimer Type|COMPLETED|PHASE4|INTERVENTIONAL","NCT00230568|EARTH 413: A Study of Aricept in Hispanic Patients With Mild to Moderate Alzheimer's Disease (AD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00234637|Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment|COMPLETED|PHASE4|INTERVENTIONAL","NCT00245206|Side Effects of Newer Antipsychotics in Older Adults|COMPLETED|PHASE4|INTERVENTIONAL","NCT00254033|Apathy Associated With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00260624|Escitalopram Treatment of Patients With Agitated Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT00303277|Do HMG CoA Reductase Inhibitors Affect Abeta Levels?|COMPLETED|PHASE4|INTERVENTIONAL","NCT00305903|Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00306124|Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00334906|Study of Memantine in Assessment of Selected Measures of Volumetric Magnetic Resonance Imaging (MRI) and Cognition in Moderate AD (Alzheimer's Disease)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00369603|Functional Brain Imaging of Medication Treatment Response in Mild Alzheimer's Disease Patients|TERMINATED|PHASE4|INTERVENTIONAL","NCT00371059|Memantine for Agitation in Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT00375557|Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00381381|The Clinical Response of Choline Acetyltransferase and Apolipoprotein Epsilon Gene Polymorphisms to Donepezil in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00385684|Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00401167|Memantine for Agitation and Aggression in Severe Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00403520|Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers|COMPLETED|PHASE4|INTERVENTIONAL","NCT00417482|Antipsychotic Discontinuation in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00433121|Discontinuation of Antipsychotics and Antidepressants Among Patients With BPSD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00443014|The Dementia Study in Northern Norway|COMPLETED|PHASE4|INTERVENTIONAL","NCT00450047|Study on the Efficacy of Speed-Feedback Therapy for Elderly People With Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT00469456|Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00476008|Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00477659|Neural Correlates In Mild Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00480870|The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00495820|Methylphenidate for Apathy in Alzheimer's Dementia: A Controlled Study|COMPLETED|PHASE4|INTERVENTIONAL","NCT00523666|Diffusion Tensor Weighted MRI in Alzheimer's Disease Modifying Treatment Effects of Galantamine (Reminyl®)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00549601|Convenience, Tolerability, and Safety of Change in the Administration of Rivastigmine From Capsules to a Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00551161|Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00561392|Clinical Effectiveness of 10 cm^2 Rivastigmine Patch in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00594269|Dementia Antipsychotics And Antidepressants Discontinuation Study|COMPLETED|PHASE4|INTERVENTIONAL","NCT00622713|A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm^2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (EXTRA)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00626210|Modafinil Treatment for Sleep/Wake Disturbances in Older Adults|TERMINATED|PHASE4|INTERVENTIONAL","NCT00626613|The Relationship Between Risperdal Treatment and Quality of Life in Patients With Alzheimer's Disease and Behavioural and Psychological Symptoms of Dementia (BPSD)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00649220|Memantine and Antipsychotics Use|TERMINATED|PHASE4|INTERVENTIONAL","NCT00706186|Safety and Feasibility of Sodium Oxybate in Mild Alzheimer's Disease Patients|TERMINATED|PHASE4|INTERVENTIONAL","NCT00711204|Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00731224|Compliance and Tolerability of Rivastigmine Transdermal Patch 10 cm² in Patients With Probable Alzheimer's Disease.|COMPLETED|PHASE4|INTERVENTIONAL","NCT00768261|Corticolimbic Degeneration and Treatment of Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT00792662|Improving Function, Quality of Life, Glycemia in Diabetics With Dementia|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00800709|Memantine and Changes of Biological Markers and Brain PET Imaging in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00814658|The Use of Galantamine (Reminyl ER) in Patients With MIXed Dementia: Effects on Cognition and Quality of Life|COMPLETED|PHASE4|INTERVENTIONAL","NCT00862940|A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00914095|Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease (PARKGAIT-II)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00933608|Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00948766|Effects of Rivastigmine Patch on Activities of Daily Living and Cognition in Patients With Severe Dementia of the Alzheimer's Type (ACTION) (Study Protocol CENA713DUS44, NCT00948766) and a 24 Week Open-label Extension to Study CENA713DUS44|COMPLETED|PHASE4|INTERVENTIONAL","NCT00950430|Imaging of Brain Amyloid Plaques in the Aging Population|ENROLLING_BY_INVITATION|PHASE4|INTERVENTIONAL","NCT00980785|Studying the Effects of Antihypertensives on Individuals at Risk for Alzheimer's|COMPLETED|PHASE4|INTERVENTIONAL","NCT01012830|Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01025466|Exelon Patch and Combination With Memantine Comparative Trial|COMPLETED|PHASE4|INTERVENTIONAL","NCT01047579|A 12 Week, Multicenter, Open Label Evaluation of Caregiver Preference, Safety and Tolerability of Exelon® Patch (Rivastigmine Transdermal) in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01054976|The Efficacy of Galantamine Treatment on Attention in Patients With Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01109836|Austrian Polyintervention Study to Prevent Cognitive Decline After Ischemic Stroke|COMPLETED|PHASE4|INTERVENTIONAL","NCT01119638|Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone|COMPLETED|PHASE4|INTERVENTIONAL","NCT01122329|A Positron Emission Tomography (PET) Study Evaluating Brain Metabolism of a Medical Food in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01142336|Effects of Simvastatin on Biomarkers|COMPLETED|PHASE4|INTERVENTIONAL","NCT01181921|The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease|TERMINATED|PHASE4|INTERVENTIONAL","NCT01295957|Alzheimer's Disease Reminiscence Quality of Life|COMPLETED|PHASE4|INTERVENTIONAL","NCT01340950|Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China|COMPLETED|PHASE4|INTERVENTIONAL","NCT01354444|Trial of Carvedilol in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01409564|Cilostazol Augmentation Study in Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT01453127|DaTSCAN Imaging in Aging and Neurodegenerative Disease|ENROLLING_BY_INVITATION|PHASE4|INTERVENTIONAL","NCT01454453|Optimisation of Antipsychotic Drug Use in Older People|TERMINATED|PHASE4|INTERVENTIONAL","NCT01478633|Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil|COMPLETED|PHASE4|INTERVENTIONAL","NCT01529619|Efficacy, Safety and Tolerability of Rivastigmine Patch in Patients With Mild to Moderate Alzheimer's Disease Switched From Cholinesterase Inhibitors|COMPLETED|PHASE4|INTERVENTIONAL","NCT01585272|Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT01703702|Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and the Relationship Between Scan Status and Cognitive Decline|COMPLETED|PHASE4|INTERVENTIONAL","NCT01799941|Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01822951|Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT)|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT01825577|Exploring the Use of Transdermal Methylphenidate to Reduce Fall Risk in Patients With Dementia.|TERMINATED|PHASE4|INTERVENTIONAL","NCT01832350|Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer's Disease|TERMINATED|PHASE4|INTERVENTIONAL","NCT01841125|Escitalopram for the Treatment of Depression in Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01849042|Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01921972|The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01946243|The Feasibility of Florbetapir Quantitation|COMPLETED|PHASE4|INTERVENTIONAL","NCT01948791|16w Interventional Study on Titration and Dose/Efficacy Assessment of Exelon in Chinese Alzheimer's Disease Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT01951118|Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly|COMPLETED|PHASE4|INTERVENTIONAL","NCT01993836|Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care|COMPLETED|PHASE4|INTERVENTIONAL","NCT02051790|Evaluation of Reader Training Processes|COMPLETED|PHASE4|INTERVENTIONAL","NCT02097056|Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT02107599|The Feasibility of Florbetapir Quantitation in Europe|COMPLETED|PHASE4|INTERVENTIONAL","NCT02190084|Repetitive Transcranial Magnetic Stimulation for Apathy in Alzheimer's Dementia|COMPLETED|PHASE4|INTERVENTIONAL","NCT02267057|Efficacy of Pain Treatment on Depression in Patients With Dementia|COMPLETED|PHASE4|INTERVENTIONAL"]}]}