{"context":{"query":">>mondo>>clinical_trials","source_dataset":"mondo","target_dataset":"clinical_trials"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]MONDO:0005002,73,MONDO:0005002,134,0]["},"schema":"id|brief_title|overall_status|phase|study_type","mappings":[{"input":"MONDO:0005002","source":"MONDO:0005002|chronic obstructive pulmonary disease","targets":["NCT00120978|Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00134979|Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combination With Formoterol Certihaler in Patients With Stable Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00158847|Modification Of Disease Outcome In COPD|TERMINATED|PHASE4|INTERVENTIONAL","NCT00170222|Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00175565|Inhaled Steroid Reduces Systemic Inflammation in COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00181207|Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation|COMPLETED|PHASE4|INTERVENTIONAL","NCT00186706|Selenium Supplementation in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00190437|ANTEAB: a Study of Early Antibiotherapy in the ICU Management of Acute Exacerbations of COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00202176|Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00202189|Effects of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00232674|Efficacy Study of the Effect of Budesonide on Emphysema|COMPLETED|PHASE4|INTERVENTIONAL","NCT00288548|Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00291408|Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00291460|Inspiratory Muscle Training in Hypercapnic COPD|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00292838|Relative Potency of Inhaled Corticosteroids|COMPLETED|PHASE4|INTERVENTIONAL","NCT00311961|Intravenous Versus Oral Administration of Prednisolone in Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00316992|Safety of Ramelteon in Subjects With Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00331656|Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure.|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00335621|Replacement of Nebulised Ipratropium With Inhaled Tiotropium in Stable Chronic Obstructive Pulmonary Disease (COPD)|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00354354|Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00379028|Airway Clearance Study|COMPLETED|PHASE4|INTERVENTIONAL","NCT00384566|A Comparison of the Effect of Carvedilol and Metoprolol on Airways Tone in Patients With Heart Failure|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00405236|Effect of Tiotropium on Inflammation and Exacerbations in COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00412204|Study to Evaluate the Effects of Tiotropium Bromide on Chronic Obstructive Pulmonary Disease (COPD) During Exercise|COMPLETED|PHASE4|INTERVENTIONAL","NCT00424528|Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00440245|Bronchoprotection of Salbutamol in Asthma and Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00440687|Withdrawal of Inhaled Corticosteroids in Patients With COPD in Primary Care|COMPLETED|PHASE4|INTERVENTIONAL","NCT00489853|Evaluation of Efficacy on Exercise Tolerance of Symbicort (Budesonide/Formoterol) Compared to Placebo and Oxis in Patients With Severe COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00491803|Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00495586|Effectiveness of Antibiotic Therapy for Exacerbations of Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00525564|Effects of Salmeterol on Walking Capacity in Patients With COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00532584|Effect of Steroids on Gene Expression in the Healthy Smokers Lungs|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00542880|Evaluation of Onset of Effect in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD) Treated With Symbicort® Compared to Seretide®|COMPLETED|PHASE4|INTERVENTIONAL","NCT00561886|Change of Inspiratory Peak Flow in COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00569270|Dynamic Hyperinflation and Tiotropium|COMPLETED|PHASE4|INTERVENTIONAL","NCT00571428|Efficacy Safety Study of Arformoterol QD Dosing Versus BID Dosing in COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00578968|Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of Bronchodilation|COMPLETED|PHASE4|INTERVENTIONAL","NCT00592033|Effect of Oxygen in Normoxaemic COPD Patients Who Desaturate During Exercise|COMPLETED|PHASE4|INTERVENTIONAL","NCT00628225|Smoking Cessation in Patients With COPD (SMOCC) in General Practice|COMPLETED|PHASE4|INTERVENTIONAL","NCT00633776|Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00639236|Effectiveness and Safety of Inhaling Hypertonic Saline in Patients With Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00666367|Vitamin D as Treatment for Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00667797|Costs & Outcomes of Hospitalization/Treatment With Levalbuterol & Albuterol in Asthma or Chronic Obstructive Pulmonary Disease (COPD) Subjects|COMPLETED|PHASE4|INTERVENTIONAL","NCT00680641|Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00720226|Efficacy of Losartan in Preventing Progression of COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00730067|Sildenafil for Chronic Obstructive Pulmonary Disease (COPD) Associated Pulmonary Hypertension|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT00730301|EUROPT Clinical Trial to Study the Efficacy of One-Way Valve Implantation (New Treatment Algorithm) in Patients With Heterogeneous Emphysema|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00731770|Comparing Fluticasone-salmeterol in Chronic Obstructive Pulmonary Disease (COPD) and Sleep|COMPLETED|PHASE4|INTERVENTIONAL","NCT00754546|Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00773786|Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00783250|Bronchodilators and Respiratory Mechanics in Chronic Obstructive Pulmonary Disease (COPD) Patients|TERMINATED|PHASE4|INTERVENTIONAL","NCT00826748|Effect of Inhaled Steroids on Gene Expression in the Lungs - 2|TERMINATED|PHASE4|INTERVENTIONAL","NCT00832611|Study of the Effect of the ROX AC1 on Exercise Capacity and Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00857038|Doxycycline and Airway Inflammation in Chronic Obstructive Pulmonary Disease (COPD)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00860938|Predictor for an Additional Benefit of Inhaled Corticosteroid in Patients Treated With Tiotropium for COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00864812|Clinical Outcomes of Tiotropium Plus Fluticasone Propionate/Salmeterol Compared With Tiotropium for Chronic Obstructive Pulmonary Disease (COPD) in Korea|COMPLETED|PHASE4|INTERVENTIONAL","NCT00911651|Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00921921|Does Extra-fine Hydrofluoroalkane-beclomethasone Dipropionate (HFA-BDP) Suppress Small Airways Inflammation in Chronic Obstructive Pulmonary Disease (COPD)?|COMPLETED|PHASE4|INTERVENTIONAL","NCT00935181|Respiratory Muscle Stretching in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT00969904|Pilot Study to Assess the Effect of High Dose N-acetylcysteine (NAC) in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT00974246|The Effect on Depressive Symptoms in ECF Residents With COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT00974805|An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00994552|Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure|UNKNOWN|PHASE4|INTERVENTIONAL","NCT00995475|A Proof of Concept Study to Evaluate the Dose Response for the Systemic Benefit Risk Ratio of Inhaled Fluticasone Propionate in Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT00996697|Differential Trough Effects of 'Triple Therapy' on Pulmonary Function in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01010178|Can Airflow Limitation in Chronic Obstructive Pulmonary Disease (COPD) be Reversible by Drugs?|COMPLETED|PHASE4|INTERVENTIONAL","NCT01014338|Angiotensin-converting Enzyme (ACE)-Inhibition and Mechanisms of Skeletal Muscle Weakness in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01037387|Effect of Noninvasive Ventilation on Physical Activity and Inflammation in COPD Patients|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01055405|Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary Hypertension|COMPLETED|PHASE4|INTERVENTIONAL","NCT01091493|Antibiotic or Not in Non-purulent Exacerbations of COPD: a Trial of Security and Efficacy|COMPLETED|PHASE4|INTERVENTIONAL","NCT01116063|Inhaled Iloprost for Disproportionate Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease (COPD)|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01131806|Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01136239|The Effect of High Dose N-acetylcysteine on Airtrapping and Airway Resistance in Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT01150383|SCOPE-Study: Salzburg Chronic Obstructive Pulmonary Disease- Exercise and Oxygen Study|COMPLETED|PHASE4|INTERVENTIONAL","NCT01151306|The Effect of Statins in Patients With Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01151579|Effect of Nebulized Bronchodilators on Heart Rate|COMPLETED|PHASE4|INTERVENTIONAL","NCT01176318|Erdosteine (Erdotin) Versus Standard Care Plus Placebo on Erdosteine for Treatment of Cough in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT01186653|Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01241526|The COPD Patient Management European Trial (COMET)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01243788|The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01247870|Metformin in Chronic Obstructive Pulmonary Disease|COMPLETED|PHASE4|INTERVENTIONAL","NCT01272362|To Determine the Relationship Between Baseline Reversibility and the Efficacy of Indacaterol|COMPLETED|PHASE4|INTERVENTIONAL","NCT01281748|Evaluation Of The Efficacy Of Corticosteroids In Patients With An Acute Exacerbation Of Chronic Obstructive Pulmonary Disease Receiving Ventilator Support|TERMINATED|PHASE4|INTERVENTIONAL","NCT01307189|Effects of Tiotropium on Walking Capacity in Patients With COPD|COMPLETED|PHASE4|INTERVENTIONAL","NCT01329029|Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01329276|Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients.|COMPLETED|PHASE4|INTERVENTIONAL","NCT01361984|Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01363531|Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies|COMPLETED|PHASE4|INTERVENTIONAL","NCT01377051|Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea|COMPLETED|PHASE4|INTERVENTIONAL","NCT01377428|Efficacy of Indacaterol 150 µg Versus Formoterol|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT01378520|Effect of Ketoconazole on Breathlessness|COMPLETED|PHASE4|INTERVENTIONAL","NCT01381367|PPSV23 Pneumococcal Vaccine in Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01382368|Acute Effect of Sildenafil on Exercise Tolerance and Functional Capacity in COPD, IPF and Post Pneumonectomy Patients|UNKNOWN|PHASE4|INTERVENTIONAL","NCT01397890|Efficacy and Tolerability of Symbicort as an add-on Treatment to Spiriva Compare With Spiriva Alone in Patients With Severe Chronic Obstructive Pulmonary Disease (COPD)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01415518|Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients|COMPLETED|PHASE4|INTERVENTIONAL","NCT01416701|Vitamin D and Chronic Obstructive Lung Disease|WITHDRAWN|PHASE4|INTERVENTIONAL","NCT01437748|Closing Volume Interpretation and Bronchodilators Effect|COMPLETED|PHASE4|INTERVENTIONAL","NCT01443845|Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)|COMPLETED|PHASE4|INTERVENTIONAL","NCT01455129|Tiotropium In Early Chronic Obstructive Pulmonary Disease Patients in China|COMPLETED|PHASE4|INTERVENTIONAL","NCT01460108|AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation|UNKNOWN|PHASE4|INTERVENTIONAL"]}]}