{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":6,"total":151,"mapped":5},"pagination":{"has_next":false},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"O14746","source":"O14746|Telomerase reverse transcriptase","targets":["2BCK|Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide|X-RAY DIFFRACTION|2.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","4B18|The crystal structure of human Importin alpha 5 with TERT NLS peptide|X-RAY DIFFRACTION|2.52|HOMO SAPIENS; SYNTHETIC CONSTRUCT|0|TRANSPORT PROTEIN / PEPTIDE","4MNQ|TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions|X-RAY DIFFRACTION|2.742|Homo sapiens; Pan troglodytes; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","5MEN|Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor|X-RAY DIFFRACTION|2.81|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","5MEO|Human Leukocyte Antigen presenting ILGKFLHRL|X-RAY DIFFRACTION|1.772|Homo sapiens|0|IMMUNE SYSTEM","5MEP|Human Leukocyte Antigen A02 presenting ILGKFLHWL|X-RAY DIFFRACTION|2.71|Homo sapiens|0|IMMUNE SYSTEM","5MEQ|Human Leukocyte Antigen A02 presenting ILAKFLHTL|X-RAY DIFFRACTION|2.27|Homo sapiens|0|IMMUNE SYSTEM","5MER|Human Leukocyte Antigen A02 presenting ILAKFLHEL|X-RAY DIFFRACTION|1.88|Homo sapiens|0|IMMUNE SYSTEM","5UGW|STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN|X-RAY DIFFRACTION|2.31|Homo sapiens|0|TRANSFERASE","7BG9|The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate|ELECTRON MICROSCOPY|3.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","7QXA|Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)|ELECTRON MICROSCOPY|3.2|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","7QXB|Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)|ELECTRON MICROSCOPY|3.9|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","7QXS|Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)|ELECTRON MICROSCOPY|3.9|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","7TRD|Human telomerase catalytic core structure at 3.3 Angstrom|ELECTRON MICROSCOPY|3.3|Homo sapiens; SYNTHETIC CONSTRUCT|0|REPLICATION","7TRE|Human telomerase catalytic core with shelterin protein TPP1|ELECTRON MICROSCOPY|3.5|Homo sapiens; SYNTHETIC CONSTRUCT|0|REPLICATION","7TRF|Human telomerase catalytic core RNP with H2A/H2B|ELECTRON MICROSCOPY|3.7|Homo sapiens; SYNTHETIC CONSTRUCT|0|REPLICATION","7V99|catalytic core of human telomerase holoenzyme|ELECTRON MICROSCOPY|3.54|Homo sapiens; SYNTHETIC CONSTRUCT|0|REPLICATION","9QAX|The catalytic core with C2 symmetry of human telomerase dimer|ELECTRON MICROSCOPY|3.3|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","9QAY|Catalytic core 1 of dimeric human telomerase|ELECTRON MICROSCOPY|3.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|DNA BINDING PROTEIN","9QAZ|Catalytic core 2 of dimeric human telomerase|ELECTRON MICROSCOPY|3.6|Homo sapiens; SYNTHETIC CONSTRUCT|0|DNA BINDING PROTEIN","9SHY|Cryo-EM structure of the catalytic core of human telomerase at the initiation state of the repeat addition cycle|ELECTRON MICROSCOPY|3.53|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","9SHZ|Cryo-EM structure of the catalytic core of human telomerase at the elongation state of the repeat addition cycle|ELECTRON MICROSCOPY|3.2|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN","9SI0|Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle|ELECTRON MICROSCOPY|3.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|RNA BINDING PROTEIN"]},{"input":"P84022","source":"P84022|SMAD family member 3","targets":["1MHD|CRYSTAL STRUCTURE OF A SMAD MH1 DOMAIN BOUND TO DNA|X-RAY DIFFRACTION|2.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|COMPLEX (TRANSCRIPTION ACTIVATOR/DNA)","1MJS|MH2 domain of transcriptional factor SMAD3|X-RAY DIFFRACTION|1.91|Homo sapiens|0|TRANSCRIPTION","1MK2|SMAD3 SBD complex|X-RAY DIFFRACTION|2.74|Homo sapiens|0|TRANSCRIPTION","1OZJ|Crystal structure of Smad3-MH1 bound to DNA at 2.4 A resolution|X-RAY DIFFRACTION|2.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSCRIPTION/DNA","1U7F|Crystal Structure of the phosphorylated Smad3/Smad4 heterotrimeric complex|X-RAY DIFFRACTION|2.6|Homo sapiens|0|SIGNALING PROTEIN","2LAJ|Third WW domain of human Nedd4L in complex with doubly phosphorylated human smad3 derived peptide|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE/TRANSCRIPTION REGULATOR","2LB2|Structure of the second domain of human Nedd4L in complex with a phosphorylated pTPY motif derived from human Smad3|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/TRANSCRIPTION","5OD6|Crystal structure of Smad3-MH1 bound to the GGCGC site.|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSCRIPTION","5ODG|Crystal structure of Smad3-MH1 bound to the GGCT site.|X-RAY DIFFRACTION|2.12|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSCRIPTION","5XOC|Crystal structure of human Smad3-FoxH1 complex|X-RAY DIFFRACTION|2.4|Escherichia coli (strain K12); Homo sapiens|0|TRANSCRIPTION","6YIB|14-3-3 sigma in complex with SMAD3 pS423 peptide|X-RAY DIFFRACTION|1.7|Homo sapiens; SYNTHETIC CONSTRUCT|0|PEPTIDE BINDING PROTEIN","6ZMN|Crystal structure of the Smad3-Smad5 MH1 domain chimera bound to the GGCGC site|X-RAY DIFFRACTION|2.333|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN"]},{"input":"P04818","source":"P04818|Thymidylate synthase","targets":["1HVY|Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation|X-RAY DIFFRACTION|1.9|Homo sapiens|0|TRANSFERASE","1HW3|STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","1HW4|STRUCTURE OF THYMIDYLATE SYNTHASE SUGGESTS ADVANTAGES OF CHEMOTHERAPY WITH NONCOMPETITIVE INHIBITORS|X-RAY DIFFRACTION|2.06|Homo sapiens|0|TRANSFERASE","1HZW|CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","1I00|CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX|X-RAY DIFFRACTION|2.5|Homo sapiens|0|TRANSFERASE","1JU6|Human Thymidylate Synthase Complex with dUMP and LY231514, A Pyrrolo(2,3-d)pyrimidine-based Antifolate|X-RAY DIFFRACTION|2.89|Homo sapiens|0|TRANSFERASE","1JUJ|Human Thymidylate Synthase Bound to dUMP and LY231514, a Pyrrolo(2,3-d)pyrimidine-based Antifolate|X-RAY DIFFRACTION|3|Homo sapiens|0|TRANSFERASE","1YPV|Structure of human thymidylate synthase at low salt conditions|X-RAY DIFFRACTION|1.8|Homo sapiens|0|TRANSFERASE","2ONB|Human Thymidylate Synthase at low salt conditions with PDPA bound|X-RAY DIFFRACTION|2.7|Homo sapiens|0|TRANSFERASE","2RD8|Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195|X-RAY DIFFRACTION|2.5|Homo sapiens|0|TRANSFERASE","2RDA|Human Thymidylate Synthase Stabilized in Active Conformation by R163K Mutation: Asymmetry and Reactivity of Cys195|X-RAY DIFFRACTION|2.67|Homo sapiens|0|TRANSFERASE","3EAW|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|1.86|Homo sapiens|0|TRANSFERASE","3EBU|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|2.05|Homo sapiens|0|TRANSFERASE","3ED7|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|1.56|Homo sapiens|0|TRANSFERASE","3EDW|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|1.75|Homo sapiens|0|TRANSFERASE","3EF9|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|3.2|Homo sapiens|0|TRANSFERASE","3EGY|Crystal Structure of Human Thymidyalte Synthase A191K with Loop 181-197 stabilized in the inactive conformation|X-RAY DIFFRACTION|2.18|Homo sapiens|0|TRANSFERASE","3EHI|Crystal Structure of Human Thymidyalte Synthase M190K with Loop 181-197 stabilized in the inactive conformation|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","3EJL|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|3.2|Homo sapiens|0|TRANSFERASE","3GG5|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|2.77|Homo sapiens|0|TRANSFERASE","3GH0|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|1.56|Homo sapiens|0|TRANSFERASE","3GH2|Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability|X-RAY DIFFRACTION|1.75|Homo sapiens|0|TRANSFERASE","3H9K|Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry|X-RAY DIFFRACTION|2.65|Homo sapiens|0|TRANSFERASE","3HB8|Structures of Thymidylate Synthase R163K with Substrates and Inhibitors Show Subunit Asymmetry|X-RAY DIFFRACTION|2.74|Homo sapiens|0|TRANSFERASE","3N5E|Crystal Structure of human thymidylate synthase bound to a peptide inhibitor|X-RAY DIFFRACTION|2.26|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE/TRANSFERASE INHIBITOR","3N5G|Crystal Structure of histidine-tagged human thymidylate synthase|X-RAY DIFFRACTION|2.27|Homo sapiens|0|TRANSFERASE","3OB7|Human Thymidylate Synthase R163K with Cys 195 covalently modified by Glutathione|X-RAY DIFFRACTION|2.75|Homo sapiens|0|TRANSFERASE","4E28|Structure of human thymidylate synthase in inactive conformation with a novel non-peptidic inhibitor|X-RAY DIFFRACTION|2.302|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4FGT|Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|transferase/transferase inhibitor","4G2O|Human Thymidylate Synthase M190K with bound Purpurogallin|X-RAY DIFFRACTION|2.25|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4G6W|Human Thymidylate Synthase M190K with bound 4-Bromobenzene-1,2,3-triol|X-RAY DIFFRACTION|2.3|Homo sapiens|0|TRANSFERASE","4GD7|Wild-Type Human Thymidylate Synthase with bound Purpurogallin|X-RAY DIFFRACTION|2.29|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4GYH|Structure of human thymidylate synthase at high salt conditions|X-RAY DIFFRACTION|3.005|Homo sapiens|0|TRANSFERASE","4H1I|Structure of human thymidylate synthase at low salt conditions|X-RAY DIFFRACTION|3.095|Homo sapiens|0|TRANSFERASE","4JEF|Crystal structure of human thymidylate synthase Y202A in inactive conformation.|X-RAY DIFFRACTION|2.311|Homo sapiens|0|TRANSFERASE","4KPW|Crystal structure of His-tagged human thymidylate synthase R175A mutant|X-RAY DIFFRACTION|2.03|Homo sapiens|0|TRANSFERASE","4O1U|Crystal structure of human thymidylate synthase mutant Y202C|X-RAY DIFFRACTION|2.26|Homo sapiens|0|TRANSFERASE","4O1X|Crystal structure of human thymidylate synthase double mutant C195S-Y202C|X-RAY DIFFRACTION|2.32|Homo sapiens|0|TRANSFERASE","4UP1|Crystal structure of native human Thymidylate synthase in active form|X-RAY DIFFRACTION|2.991|HOMO SAPIENS|0|TRANSFERASE","5HS3|Human thymidylate synthase complexed with dUMP and 3-amino-2-benzoyl-4-methylthieno[2,3-b]pyridin-6-ol|X-RAY DIFFRACTION|3.103|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","5WRN|Human thymidylate synthase complexed with dCMP|X-RAY DIFFRACTION|2.39|Homo sapiens|0|TRANSFERASE","5X4W|Mutant human thymidylate synthase A191K crystallized in a sulfate-free condition|X-RAY DIFFRACTION|2.1|Homo sapiens|0|TRANSFERASE","5X4X|Mutant human thymidylate synthase A191K crystallized in a sulfate-containing condition|X-RAY DIFFRACTION|2.31|Homo sapiens|0|TRANSFERASE","5X4Y|Mutant human thymidylate synthase M190K crystallized in a sulfate-containing condition|X-RAY DIFFRACTION|2.2|Homo sapiens|0|TRANSFERASE","5X5A|Human thymidylate synthase bound with phosphate ion|X-RAY DIFFRACTION|2.39|Homo sapiens|0|TRANSFERASE","5X5D|Human thymidylate synthase bound with dUMP|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","5X5Q|Human thymidylate synthase complexed with dUMP and raltitrexed|X-RAY DIFFRACTION|2.79|Homo sapiens|0|TRANSFERASE","5X66|Human thymidylate synthase in complex with dUMP and methotrexate|X-RAY DIFFRACTION|1.99|Homo sapiens|0|TRANSFERASE","5X67|Human thymidylate synthase in complex with dUMP and nolatrexed|X-RAY DIFFRACTION|2.13|Homo sapiens|0|TRANSFERASE","5X69|Human thymidylate synthase with a fragment bound in the dimer interface|X-RAY DIFFRACTION|2.69|Homo sapiens|0|TRANSFERASE","6OJU|Crystal structure of human thymidylate synthase Delta (7-29) in complex with dUMP and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-D-glutamic acid|X-RAY DIFFRACTION|2.884|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","6OJV|Crystal structure of human thymidylate synthase delta(7-29) in complex with dUMP and 2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidine-methyl-phenyl-L-glutamic acid|X-RAY DIFFRACTION|2.593|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","6PF3|Crystal structure of human thymidylate synthase Delta (7-29) in complex with dUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-chlorobenzoic acid|X-RAY DIFFRACTION|2.391|Homo sapiens|0|transferase/transferase inhibitor","6PF4|Crystal structure of human thymidylate synthase Delta (7-29) in complex with dUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)phenyl)acetic acid|X-RAY DIFFRACTION|2.854|Homo sapiens|0|transferase/transferase inhibitor","6PF5|Crystal structure of human thymidylate synthase Delta (7-29) in complex with dUMP and 2-(2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)-4-methoxyphenyl)acetic acid|X-RAY DIFFRACTION|2.39|Homo sapiens|0|transferase/transferase inhibitor","6PF6|Crystal structure of TS-DHFR from Cryptosporidium hominis in complex with NADPH, FdUMP and 2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl)benzamido)terephthalic acid|X-RAY DIFFRACTION|2.502|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","6QXG|Crystal structure of His-tag human thymidylate synthase (HT-hTS) in complex with FdUMP|X-RAY DIFFRACTION|2.08|Homo sapiens|0|TRANSFERASE","6QXH|Crystal structure of His-tag human thymidylate synthase (HT-hTS) in complex with dUMP|X-RAY DIFFRACTION|2.04|Homo sapiens|0|TRANSFERASE","6QYQ|Crystal structure of human thymidylate synthase (hTS) variant R175C|X-RAY DIFFRACTION|2.25|Homo sapiens|0|TRANSFERASE","6R2E|Crystal structure of the human thymidylate synthase (hTS) interface variant Q62R|X-RAY DIFFRACTION|2.55|Homo sapiens|0|TRANSFERASE","6ZXO|Crystal structure of His-tagged human thymidylate synthase (HT-hTS) in complex with FdUMP and Raltitrexed (Tomudex)|X-RAY DIFFRACTION|2.6|Homo sapiens|0|TRANSFERASE"]},{"input":"P06241","source":"P06241|Tyrosine-protein kinase Fyn","targets":["1A0N|NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES|SOLUTION NMR||Homo sapiens|0|COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)","1AOT|NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE|SOLUTION NMR||Hamster polyomavirus; Homo sapiens|0|COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)","1AOU|NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES|SOLUTION NMR||Hamster polyomavirus; Homo sapiens|0|COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN)","1AVZ|V-1 NEF PROTEIN IN COMPLEX WITH WILD TYPE FYN SH3 DOMAIN|X-RAY DIFFRACTION|3|Homo sapiens; Human immunodeficiency virus 1|0|COMPLEX (MYRISTYLATION/TRANSFERASE)","1AZG|NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE|SOLUTION NMR||Homo sapiens|0|COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE)","1EFN|HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN|X-RAY DIFFRACTION|2.5|Homo sapiens; Human immunodeficiency virus 1|0|COMPLEX (SH3 DOMAIN/VIRAL ENHANCER)","1FYN|PHOSPHOTRANSFERASE|X-RAY DIFFRACTION|2.3|Homo sapiens|0|TRANSFERASE","1G83|CRYSTAL STRUCTURE OF FYN SH3-SH2|X-RAY DIFFRACTION|2.6|Homo sapiens|0|TRANSFERASE","1M27|Crystal structure of SAP/FynSH3/SLAM ternary complex|X-RAY DIFFRACTION|2.5|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN, TRANSFERASE","1NYF|NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE|SOLUTION NMR||Homo sapiens|0|PHOSPHOTRANSFERASE","1NYG|NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, FAMILY OF 20 STRUCTURES|SOLUTION NMR||Homo sapiens|0|PHOSPHOTRANSFERASE","1SHF|CRYSTAL STRUCTURE OF THE SH3 DOMAIN IN HUMAN FYN; COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF SH3 DOMAINS IN TYROSINE KINASES AND SPECTRIN|X-RAY DIFFRACTION|1.9|Homo sapiens|0|PHOSPHOTRANSFERASE","1ZBJ|Inferential Structure Determination of the Fyn SH3 domain using NOESY data from a 15N,H2 enriched protein|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","2DQ7|Crystal Structure of Fyn kinase domain complexed with staurosporine|X-RAY DIFFRACTION|2.8|Homo sapiens|0|TRANSFERASE","2MQI|human Fyn SH2 free state|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","2MRJ|Structure of Fyn protein SH2 bound|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","2MRK|Fyn SH2 domain in complex with the natural inhibitory phosphotyrosine peptide|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE","3H0F|Crystal structure of the human Fyn SH3 R96W mutant|X-RAY DIFFRACTION|2.61|Homo sapiens|0|TRANSFERASE","3H0H|human Fyn SH3 domain R96I mutant, crystal form I|X-RAY DIFFRACTION|1.76|Homo sapiens|0|TRANSFERASE","3H0I|human Fyn SH3 domain R96I mutant, crystal form II|X-RAY DIFFRACTION|2.2|Homo sapiens|0|TRANSFERASE","3UA6|Crystal Structure of the Human Fyn SH3 domain|X-RAY DIFFRACTION|1.85|Homo sapiens|0|TRANSFERASE","3UA7|Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein|X-RAY DIFFRACTION|1.5|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE/VIRAL PROTEIN","4D8D|Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant|X-RAY DIFFRACTION|2.5201|Homo sapiens; Human immunodeficiency virus type 1|0|TRANSFERASE/PROTEIN BINDING","4EIK|Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12|X-RAY DIFFRACTION|1.6|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE/PROTEIN BINDING","4U17|Swapped dimer of the human Fyn-SH2 domain|X-RAY DIFFRACTION|1.99|Homo sapiens|0|TRANSFERASE","4U1P|Human Fyn-SH2 domain in complex with a synthetic high-affinity phospho-peptide|X-RAY DIFFRACTION|1.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE","4ZNX|Crystal structure of the Fyn-SH3 domain in complex with the high affinity peptide APP12|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5ZAU|Complex of the human FYN SH3 and monobody binder|SOLUTION NMR||Homo sapiens; Sulfolobus solfataricus|0|SIGNALING PROTEIN","6EDF|Fragment of a tyrosine-protein kinase|X-RAY DIFFRACTION|1.4|Homo sapiens|0|TRANSFERASE","6IPY|His-tagged Fyn SH3 domain R96I mutant|X-RAY DIFFRACTION|1.343|Homo sapiens|0|PROTEIN BINDING","6IPZ|Fyn SH3 domain R96W mutant, crystallized with 18-crown-6|X-RAY DIFFRACTION|1.576|Homo sapiens|0|PROTEIN BINDING","7A2J|Crystal structure of the Fyn SH3 domain in space group C21 at pH 7.5|X-RAY DIFFRACTION|1.5|Homo sapiens|0|PROTEIN BINDING","7A2K|Crystal structure of the Fyn SH3 domain in space group P1 at pH 7.5|X-RAY DIFFRACTION|1.5|Homo sapiens|0|PROTEIN BINDING","7A2L|Crystal structure of the Fyn SH3 domain mutant E129Q in space group C21 at pH 4.0|X-RAY DIFFRACTION|1.9|Homo sapiens|0|PROTEIN BINDING","7A2M|Crystal structure of the Fyn SH3 domain A95S-D99T mutant in C21 space group|X-RAY DIFFRACTION|1.5|Homo sapiens|0|PROTEIN BINDING","7A2N|Crystal structure of the Fyn SH3 domain A95S-D99T mutant in space group P21|X-RAY DIFFRACTION|1.4|Homo sapiens|0|PROTEIN BINDING","7A2O|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 4.5|X-RAY DIFFRACTION|0.94|Homo sapiens|0|PROTEIN BINDING","7A2P|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 5.0 with PEG|X-RAY DIFFRACTION|0.9|Homo sapiens|0|PROTEIN BINDING","7A2Q|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 3.0 with PEG|X-RAY DIFFRACTION|0.94|Homo sapiens|0|PROTEIN BINDING","7A2R|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 6.0|X-RAY DIFFRACTION|1.05|Homo sapiens|0|PROTEIN BINDING","7A2S|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 5.0|X-RAY DIFFRACTION|1.02|Homo sapiens|0|PROTEIN BINDING","7A2T|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 4.0|X-RAY DIFFRACTION|1.22|Homo sapiens|0|PROTEIN BINDING","7A2U|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T at pH 4.5|X-RAY DIFFRACTION|1.7|Homo sapiens|0|PROTEIN BINDING","7A2V|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E129Q at pH 4.0|X-RAY DIFFRACTION|1.81|Homo sapiens|0|PROTEIN BINDING","7A2W|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 3.0|X-RAY DIFFRACTION|0.99|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","7A2X|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 5.0|X-RAY DIFFRACTION|0.92|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","7A2Y|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 4.0|X-RAY DIFFRACTION|0.97|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","7A2Z|Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant in complex with VSL12 at pH 6.0|X-RAY DIFFRACTION|1.14|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","7UD6|Designed Enzyme SH3-588 (Catechol O-methyltransferase catalytic domain and Src homology 3 binding domain fusion)|X-RAY DIFFRACTION|2.59|Homo sapiens; Rattus norvegicus|0|TRANSFERASE","8KDX|Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current|X-RAY DIFFRACTION|1.01|Homo sapiens; SYNTHETIC CONSTRUCT|0|PEPTIDE BINDING PROTEIN","9GHK|Crystal structure of Fyn SH3 domain/tau 214-220 peptide complex|X-RAY DIFFRACTION|1.42|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","9PGZ|X-ray crystal structure of SRD42|X-RAY DIFFRACTION|2.6|Homo sapiens; Priestia megaterium|0|TRANSFERASE"]},{"input":"P01266","source":"P01266|Thyroglobulin","targets":["6SCJ|The structure of human thyroglobulin|ELECTRON MICROSCOPY|3.6|Homo sapiens|0|HORMONE","7B75|Cryo-EM Structure of Human Thyroglobulin|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|HORMONE","9I0O|Cryo-EM structure of human sortilin ectodomain in complex with a thyroglobulin C-terminal peptide|ELECTRON MICROSCOPY|3.36|Homo sapiens; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN"]}],"not_found":["O00358"]}