{"context":{"query":">>uniprot>>reactome","source_dataset":"uniprot","target_dataset":"reactome"},"stats":{"queried":8,"total":54,"mapped":8},"pagination":{"has_next":false},"schema":"id|name|tax_id|is_disease_pathway","mappings":[{"input":"O15105","source":"O15105|SMAD family member 7","targets":["R-HSA-201451|Signaling by BMP|9606|false","R-HSA-2173788|Downregulation of TGF-beta receptor signaling|9606|false","R-HSA-2173795|Downregulation of SMAD2/3:SMAD4 transcriptional activity|9606|false","R-HSA-2173796|SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription|9606|false","R-HSA-5689603|UCH proteinases|9606|false","R-HSA-5689880|Ub-specific processing proteases|9606|false","R-HSA-877300|Interferon gamma signaling|9606|false"]},{"input":"O60565","source":"O60565|Gremlin-1","targets":["R-HSA-9830674|Formation of the ureteric bud|9606|false"]},{"input":"Q9NQB0","source":"Q9NQB0|Transcription factor 7-like 2","targets":["R-HSA-201722|Formation of the beta-catenin:TCF transactivating complex|9606|false","R-HSA-3769402|Deactivation of the beta-catenin transactivating complex|9606|false","R-HSA-381771|Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)|9606|false","R-HSA-4086398|Ca2+ pathway|9606|false","R-HSA-4411364|Binding of TCF/LEF:CTNNB1 to target gene promoters|9606|false","R-HSA-4641265|Repression of WNT target genes|9606|false","R-HSA-5339700|Signaling by TCF7L2 mutants|9606|true","R-HSA-8853884|Transcriptional Regulation by VENTX|9606|false","R-HSA-8951430|RUNX3 regulates WNT signaling|9606|false","R-HSA-9823730|Formation of definitive endoderm|9606|false","R-HSA-9825892|Regulation of MITF-M-dependent genes involved in cell cycle and proliferation|9606|false","R-HSA-9909649|Regulation of PD-L1(CD274) transcription|9606|false"]},{"input":"P12830","source":"P12830|Cadherin-1","targets":["R-HSA-1474228|Degradation of the extracellular matrix|9606|false","R-HSA-198933|Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell|9606|false","R-HSA-216083|Integrin cell surface interactions|9606|false","R-HSA-351906|Apoptotic cleavage of cell adhesion  proteins|9606|false","R-HSA-418990|Adherens junctions interactions|9606|false","R-HSA-5626467|RHO GTPases activate IQGAPs|9606|false","R-HSA-8876493|InlA-mediated entry of Listeria monocytogenes into host cells|9606|true","R-HSA-9764561|Regulation of CDH1 Function|9606|false","R-HSA-9764562|Regulation of CDH1 mRNA translation by microRNAs|9606|false","R-HSA-9766229|Degradation of CDH1|9606|false","R-HSA-9768727|Regulation of CDH1 posttranslational processing and trafficking to plasma membrane|9606|false","R-HSA-9823730|Formation of definitive endoderm|9606|false","R-HSA-9856649|Transcriptional and post-translational regulation of MITF-M expression and activity|9606|false","R-HSA-9926550|Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition|9606|false","R-HSA-9927418|Developmental Lineage of Mammary Gland Luminal Epithelial Cells|9606|false","R-HSA-9927432|Developmental Lineage of Mammary Gland Myoepithelial Cells|9606|false","R-HSA-9938206|Developmental Lineage of Mammary Stem Cells|9606|false"]},{"input":"P12644","source":"P12644|Bone morphogenetic protein 4","targets":["R-HSA-2129379|Molecules associated with elastic fibres|9606|false","R-HSA-381426|Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)|9606|false","R-HSA-8957275|Post-translational protein phosphorylation|9606|false","R-HSA-9754189|Germ layer formation at gastrulation|9606|false","R-HSA-9758920|Formation of lateral plate mesoderm|9606|false","R-HSA-9761174|Formation of intermediate mesoderm|9606|false","R-HSA-9793380|Formation of paraxial mesoderm|9606|false","R-HSA-9827857|Specification of primordial germ cells|9606|false","R-HSA-9830364|Formation of the nephric duct|9606|false","R-HSA-9830674|Formation of the ureteric bud|9606|false","R-HSA-9834899|Specification of the neural plate border|9606|false"]},{"input":"P29475","source":"P29475|Nitric oxide synthase 1","targets":["R-HSA-1222556|ROS and RNS production in phagocytes|9606|false","R-HSA-392154|Nitric oxide stimulates guanylate cyclase|9606|false","R-HSA-5578775|Ion homeostasis|9606|false"]},{"input":"Q9NZ08","source":"Q9NZ08|Endoplasmic reticulum aminopeptidase 1","targets":["R-HSA-983170|Antigen Presentation: Folding, assembly and peptide loading of class I MHC|9606|false"]},{"input":"O75751","source":"O75751|Solute carrier family 22 member 3","targets":["R-HSA-2161517|Abacavir transmembrane transport|9606|false","R-HSA-549127|SLC-mediated transport of organic cations|9606|false"]}]}