{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":1,"total":61,"mapped":1},"pagination":{"has_next":false},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"P04626","source":"P04626|Receptor tyrosine-protein kinase erbB-2","targets":["1MFG|The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor|X-RAY DIFFRACTION|1.25|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","1MFL|The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor|X-RAY DIFFRACTION|1.88|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","1MW4|Solution structure of the human Grb7-SH2 domain in complex with a 10 amino acid peptide pY1139|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|HORMONE/GROWTH FACTOR/TRANSFERASE","1N8Z|Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab|X-RAY DIFFRACTION|2.52|Homo sapiens; Mus musculus, Homo sapiens|0|TRANSFERASE","1QR1|POOR BINDING OF A HER-2/NEU EPITOPE (GP2) TO HLA-A2.1 IS DUE TO A LACK OF INTERACTIONS IN THE CENTER OF THE PEPTIDE|X-RAY DIFFRACTION|2.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","1S78|Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex|X-RAY DIFFRACTION|3.25|Homo sapiens; Mus musculus|0|TRANSFERASE","2A91|Crystal structure of ErbB2 domains 1-3|X-RAY DIFFRACTION|2.5|Homo sapiens|0|SIGNALING PROTEIN,TRANSFERASE,MEMBRANE PROTEIN","2JWA|ErbB2 transmembrane segment dimer spatial structure|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","2KS1|Heterodimeric association of Transmembrane domains of ErbB1 and ErbB2 receptors Enabling Kinase Activation|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","2L4K|Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","2N2A|Spatial structure of HER2/ErbB2 dimeric transmembrane domain in the presence of cytoplasmic juxtamembrane domains|SOLUTION NMR||Homo sapiens|0|MEMBRANE PROTEIN","3BE1|Dual specific bH1 Fab in complex with the extracellular domain of HER2/ErbB-2|X-RAY DIFFRACTION|2.9|Homo sapiens|0|TRANSFERASE","3H3B|Crystal structure of the single-chain Fv (scFv) fragment of an anti-ErbB2 antibody chA21 in complex with residues 1-192 of ErbB2 extracellular domain|X-RAY DIFFRACTION|2.45|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM","3MZW|HER2 extracelluar region with affinity matured 3-helix affibody ZHER2:342|X-RAY DIFFRACTION|2.9|Homo sapiens; SYNTHETIC CONSTRUCT|0|TRANSFERASE","3N85|Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment|X-RAY DIFFRACTION|3.2|Homo sapiens|0|Transferase/immune system","3PP0|Crystal Structure of the Kinase domain of Human HER2 (erbB2).|X-RAY DIFFRACTION|2.25|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","3RCD|HER2 Kinase Domain Complexed with TAK-285|X-RAY DIFFRACTION|3.21|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","3WLW|Molecular Architecture of the ErbB2 Extracellular Domain Homodimer|X-RAY DIFFRACTION|3.088|Homo sapiens|0|HYDROLASE/IMMUNE SYSTEM","3WSQ|Structure of HER2 with an Fab|X-RAY DIFFRACTION|3.5|Homo sapiens|0|TRANSFERASE/IMMUNE SYSTEM","4GFU|PTPN18 in complex with HER2-pY1248 phosphor-peptides|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/Peptide","4HRL|Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2|X-RAY DIFFRACTION|2.55|Homo sapiens; synthetic|0|TRANSFERASE/DE NOVO PROTEIN","4HRM|Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2|X-RAY DIFFRACTION|3.2|Homo sapiens; synthetic|0|TRANSFERASE/DE NOVO PROTEIN","4HRN|Structural Basis for Eliciting a Cytotoxic Effect in HER2-Overexpressing Cancer Cells via Binding to the Extracellular Domain of HER2|X-RAY DIFFRACTION|2.65|Homo sapiens; synthetic|0|TRANSFERASE/DE NOVO PROTEIN","4NND|Structural basis of PTPN18 fingerprint on distinct HER2 tyrosine phosphorylation sites|X-RAY DIFFRACTION|2.502|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","5K33|Crystal structure of extracellular domain of HER2 in complex with Fcab STAB19|X-RAY DIFFRACTION|3.3|Homo sapiens|0|IMMUNE SYSTEM","5KWG|Crystal structure of extracellular domain of HER2 in complex with Fcab H10-03-6|X-RAY DIFFRACTION|4.3|Homo sapiens|0|IMMUNE SYSTEM","5MY6|Crystal structure of a HER2-Nb complex|X-RAY DIFFRACTION|2.246|Camelus dromedarius; Homo sapiens|0|TRANSFERASE","5O4G|HER2 in complex with Fab MF3958|X-RAY DIFFRACTION|3|Homo sapiens|0|ONCOPROTEIN","5OB4|NMR spatial structure of HER2 TM domain dimer in DPC micelles.|SOLUTION NMR||Homo sapiens|0|MEMBRANE PROTEIN","5TQS|Phospholipase C gamma-1 C-terminal SH2 domain bound to a phosphopeptide derived from the receptor tyrosine kinase ErbB2|X-RAY DIFFRACTION|1.876|Bos taurus; SYNTHETIC CONSTRUCT|0|HYDROLASE","6ATT|39S Fab bound to HER2 ecd|X-RAY DIFFRACTION|3.77|Homo sapiens|0|IMMUNE SYSTEM","6BGT|Structure of Trastuzumab Fab mutant in complex with Her2 extracellular domain|X-RAY DIFFRACTION|2.7|Homo sapiens|0|TRANSFERASE/IMMUNE SYSTEM","6J71|HuA21-scFv in complex with the extracellular domain(ECD) of HER2|X-RAY DIFFRACTION|2.918|Homo sapiens|0|SIGNALING PROTEIN","6LBX|Crystal structure of HER2 Domain IV and Rb-H2|X-RAY DIFFRACTION|2.03|Cyclostomata; Homo sapiens|0|PROTEIN BINDING","6OGE|Cryo-EM structure of Her2 extracellular domain-Trastuzumab Fab-Pertuzumab Fab complex|ELECTRON MICROSCOPY|4.36|Homo sapiens|0|transferase/immune system","7JXH|HER2 in complex with JBJ-08-178-01|X-RAY DIFFRACTION|3.27|Homo sapiens|0|TRANSFERASE/TRANSFERASE Inhibitor","7MN5|Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain|ELECTRON MICROSCOPY|2.93|Escherichia coli; Homo sapiens|0|SIGNALING PROTEIN","7MN6|Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain|ELECTRON MICROSCOPY|3.09|Escherichia coli; Homo sapiens|0|SIGNALING PROTEIN","7MN8|Structure of the HER2/HER3/NRG1b Heterodimer Extracellular Domain bound to Trastuzumab Fab|ELECTRON MICROSCOPY|3.45|Escherichia coli; Homo sapiens|0|SIGNALING PROTEIN/IMMUNE SYSTEM","7PCD|HER2 IN COMPLEX WITH A COVALENT INHIBITOR|X-RAY DIFFRACTION|1.77|Homo sapiens|0|TRANSFERASE","7QVK|NM-02 in complex with HER2-ECD|X-RAY DIFFRACTION|3.1|Camelus bactrianus; Homo sapiens|0|ONCOPROTEIN","8FFJ|Structure of Zanidatamab bound to HER2|ELECTRON MICROSCOPY|7.5|Homo sapiens|0|TRANSFERASE/IMMUNE SYSTEM","8HGO|The EGF-bound EGFR/HER2 ectodomain complex|ELECTRON MICROSCOPY|3.31|Homo sapiens|0|MEMBRANE PROTEIN","8HGP|The EREG-bound EGFR/HER2 ectodomain complex|ELECTRON MICROSCOPY|4.53|Homo sapiens|0|MEMBRANE PROTEIN","8JYQ|Crystal structure of cancer-specific anti-HER2 antibody H2Mab-214 in complex with epitope peptide|X-RAY DIFFRACTION|1.75|Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","8JYR|Crystal structure of anti-HER2 antibody H2Mab-119 in complex with HER2 domain I|X-RAY DIFFRACTION|1.69|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM","8PWH|Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex|ELECTRON MICROSCOPY|3.17|Homo sapiens|0|STRUCTURAL PROTEIN","8Q6J|Atomic structure and conformational variability of the HER2-Trastuzumab-Pertuzumab complex|ELECTRON MICROSCOPY|3.3|Homo sapiens|0|STRUCTURAL PROTEIN","8U4K|Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain|ELECTRON MICROSCOPY|4.27|Homo sapiens|0|MEMBRANE PROTEIN, TRANSFERASE","8U4L|Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain|ELECTRON MICROSCOPY|3.31|Homo sapiens|0|MEMBRANE PROTEIN, TRANSFERASE","8U8X|crystal structure of the receptor tyrosine kinase Human HER2 (ERBB2) YVMA mutant kinase domain in complex with inhibitor compound 27|X-RAY DIFFRACTION|1.69|Homo sapiens|0|SIGNALING PROTEIN,TRANSFERASE/INHIBITOR","8VB5|Crystal structure of kinase domain of HER2 Exon 20 insertion mutant in complex with tucatinib|X-RAY DIFFRACTION|1.48|Homo sapiens|0|TRANSFERASE","8VQD|HER2 S310F in complex with TL1 Fab|ELECTRON MICROSCOPY|2.61|Homo sapiens|0|SIGNALING PROTEIN","8VQE|Homodimeric structure of HER2 S310F extracellular region|ELECTRON MICROSCOPY|2.67|Homo sapiens|0|SIGNALING PROTEIN","9IUT|Crystal structure of cancer-specific anti-HER2 antibody H2Mab-250 in complex with epitope peptide|X-RAY DIFFRACTION|2.09|Mus musculus; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","9L1S|Structure of the HER2 (S310F) - pertuzumab (T30S/D31A) complex|ELECTRON MICROSCOPY|3.0|Homo sapiens|0|IMMUNE SYSTEM","9MTE|CryoEM structure of extracellular domain of human HER2 complexed with two nano-bodies 27A05 and 47D05|ELECTRON MICROSCOPY|2.66|Homo sapiens; Lama glama|0|TRANSFERASE/IMMUNE SYSTEM","9MTX|CryoEM structure of extracellular domain of human HER2 complexed with nano-bodies 29E09|ELECTRON MICROSCOPY|3.06|Homo sapiens; Lama glama|0|TRANSFERASE","9QBF|HER2/ErbB2 extracellular domain (ECD) in compact conformation in complex with trastuzumab (TZB) antibody|ELECTRON MICROSCOPY|3.8|Aequorea victoria; Homo sapiens|0|SIGNALING PROTEIN","9QBG|HER2/ErbB2 extracellular domain (ECD) in extended conformation in complex with trastuzumab (TZB) antibody|ELECTRON MICROSCOPY|3.6|Aequorea victoria; Homo sapiens|0|SIGNALING PROTEIN","9QBH|HER2/ErbB2 extracellular domain (ECD) from a near full-length construct solubilized in amphipols.|ELECTRON MICROSCOPY|3.77|Aequorea victoria; Homo sapiens|0|SIGNALING PROTEIN"]}]}