{"context":{"query":">>uniprot>>reactome","source_dataset":"uniprot","target_dataset":"reactome"},"stats":{"queried":6,"total":53,"mapped":6},"pagination":{"has_next":false},"schema":"id|name|tax_id|is_disease_pathway","mappings":[{"input":"P05067","source":"P05067|Amyloid-beta precursor protein","targets":["R-HSA-114608|Platelet degranulation |9606|false","R-HSA-3000178|ECM proteoglycans|9606|false","R-HSA-381426|Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)|9606|false","R-HSA-416476|G alpha (q) signalling events|9606|false","R-HSA-418594|G alpha (i) signalling events|9606|false","R-HSA-432720|Lysosome Vesicle Biogenesis|9606|false","R-HSA-444473|Formyl peptide receptors bind formyl peptides and many other ligands|9606|false","R-HSA-445989|TAK1-dependent IKK and NF-kappa-B activation  |9606|false","R-HSA-844456|The NLRP3 inflammasome|9606|false","R-HSA-879415|Advanced glycosylation endproduct receptor signaling|9606|false","R-HSA-8862803|Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models|9606|true","R-HSA-8957275|Post-translational protein phosphorylation|9606|false","R-HSA-933542|TRAF6 mediated NF-kB activation|9606|false","R-HSA-9609523|Insertion of tail-anchored proteins into the endoplasmic reticulum membrane|9606|false","R-HSA-9660826|Purinergic signaling in leishmaniasis infection|9606|true","R-HSA-977225|Amyloid fiber formation|9606|false","R-HSA-9837999|Mitochondrial protein degradation|9606|false"]},{"input":"P49768","source":"P49768|Presenilin-1","targets":["R-HSA-1251985|Nuclear signaling by ERBB4|9606|false","R-HSA-1474228|Degradation of the extracellular matrix|9606|false","R-HSA-193692|Regulated proteolysis of p75NTR|9606|false","R-HSA-205043|NRIF signals cell death from the nucleus|9606|false","R-HSA-2122948|Activated NOTCH1 Transmits Signal to the Nucleus|9606|false","R-HSA-2644606|Constitutive Signaling by NOTCH1 PEST Domain Mutants|9606|true","R-HSA-2894862|Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants|9606|true","R-HSA-2979096|NOTCH2 Activation and Transmission of Signal to the Nucleus|9606|false","R-HSA-3928665|EPH-ephrin mediated repulsion of cells|9606|false","R-HSA-6798695|Neutrophil degranulation|9606|false","R-HSA-9013507|NOTCH3 Activation and Transmission of Signal to the Nucleus|9606|false","R-HSA-9013700|NOTCH4 Activation and Transmission of Signal to the Nucleus|9606|false","R-HSA-9017802|Noncanonical activation of NOTCH3|9606|false","R-HSA-9839383|TGFBR3 PTM regulation|9606|false"]},{"input":"Q9NZC2","source":"Q9NZC2|Triggering receptor expressed on myeloid cells 2","targets":["R-HSA-198933|Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell|9606|false","R-HSA-2172127|DAP12 interactions|9606|false","R-HSA-2424491|DAP12 signaling|9606|false","R-HSA-416700|Other semaphorin interactions|9606|false"]},{"input":"P02649","source":"P02649|Apolipoprotein E","targets":["R-HSA-1251985|Nuclear signaling by ERBB4|9606|false","R-HSA-3000480|Scavenging by Class A Receptors|9606|false","R-HSA-381426|Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)|9606|false","R-HSA-8864260|Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors|9606|false","R-HSA-8957275|Post-translational protein phosphorylation|9606|false","R-HSA-8963888|Chylomicron assembly|9606|false","R-HSA-8963901|Chylomicron remodeling|9606|false","R-HSA-8964026|Chylomicron clearance|9606|false","R-HSA-8964058|HDL remodeling|9606|false","R-HSA-9029569|NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux|9606|false","R-HSA-975634|Retinoid metabolism and transport|9606|false","R-HSA-977225|Amyloid fiber formation|9606|false"]},{"input":"O00499","source":"O00499|Myc box-dependent-interacting protein 1","targets":["R-HSA-8856828|Clathrin-mediated endocytosis|9606|false"]},{"input":"P10909","source":"P10909|Clusterin","targets":["R-HSA-114608|Platelet degranulation |9606|false","R-HSA-166665|Terminal pathway of complement|9606|false","R-HSA-6803157|Antimicrobial peptides|9606|false","R-HSA-977606|Regulation of Complement cascade|9606|false","R-HSA-9920588|Dengue virus activates/modulates innate and adaptive immune responses|9606|true"]}]}