{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":1,"total":52,"mapped":1},"pagination":{"has_next":false},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"P10721","source":"P10721|Mast/stem cell growth factor receptor Kit","targets":["1PKG|Structure of a c-Kit Kinase Product Complex|X-RAY DIFFRACTION|2.9|Homo sapiens|0|TRANSFERASE ACTIVATOR","1T45|STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE|X-RAY DIFFRACTION|1.9|Homo sapiens|0|TRANSFERASE ACTIVATOR","1T46|STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE|X-RAY DIFFRACTION|1.6|Homo sapiens|0|TRANSFERASE ACTIVATOR","2E9W|Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)|X-RAY DIFFRACTION|3.5|Homo sapiens|0|TRANSFERASE/HORMONE","2EC8|Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit|X-RAY DIFFRACTION|3|Homo sapiens|0|TRANSFERASE","2IUH|Crystal structure of the PI3-kinase p85 N-terminal SH2 domain in complex with c-Kit phosphotyrosyl peptide|X-RAY DIFFRACTION|2|HOMO SAPIENS|0|TRANSFERASE","2VIF|Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide|X-RAY DIFFRACTION|1.45|HOMO SAPIENS|0|SIGNALING PROTEIN","3G0E|KIT kinase domain in complex with sunitinib|X-RAY DIFFRACTION|1.6|Homo sapiens|0|TRANSFERASE","3G0F|KIT kinase domain mutant D816H in complex with sunitinib|X-RAY DIFFRACTION|2.6|Homo sapiens|0|TRANSFERASE","4HVS|Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX647|X-RAY DIFFRACTION|1.9|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4K94|Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibody Fab19|X-RAY DIFFRACTION|2.4|Homo sapiens|0|IMMUNE SYSTEM","4K9E|Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibodies Fab79D|X-RAY DIFFRACTION|2.7|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM","4PGZ|Structural basis of KIT activation by oncogenic mutations in the extracellular region reveals a zipper-like mechanism for ligand-dependent or oncogenic receptor tyrosine kinase activation|X-RAY DIFFRACTION|2.4|Homo sapiens|0|TRANSFERASE","4U0I|Crystal structure of KIT in complex with ponatinib|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","6GQJ|Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 18)|X-RAY DIFFRACTION|2.33|Homo sapiens|0|SIGNALING PROTEIN","6GQK|Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 23)|X-RAY DIFFRACTION|2.31|Homo sapiens|0|SIGNALING PROTEIN","6GQL|Crystal structure of human c-KIT kinase domain in complex with AZD3229-analogue (compound 35)|X-RAY DIFFRACTION|2.01|Homo sapiens|0|SIGNALING PROTEIN","6GQM|Crystal structure of human c-KIT kinase domain in complex with a small molecule inhibitor, AZD3229|X-RAY DIFFRACTION|2|Homo sapiens|0|SIGNALING PROTEIN","6HH1|Structure of c-Kit with allosteric inhibitor 3G8|X-RAY DIFFRACTION|2.25|Homo sapiens|0|TRANSFERASE","6ITT|Crystal structure of unactivated c-KIT in complex with compound|X-RAY DIFFRACTION|2.103|Homo sapiens|0|ONCOPROTEIN","6ITV|Crystal structure of activated c-KIT in complex with compound|X-RAY DIFFRACTION|1.881|Homo sapiens|0|ONCOPROTEIN","6KLA|Crystal structure of human c-KIT kinase domain in complex with compound 15a|X-RAY DIFFRACTION|2.109|Homo sapiens|0|TRANSFERASE","6MOB|Crystal structure of KIT1 in complex with DP2976 via co-crystallization|X-RAY DIFFRACTION|1.8|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","6XV9|Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor|X-RAY DIFFRACTION|3.38|Homo sapiens|0|SIGNALING PROTEIN","6XVA|Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor bearing an acrylamide|X-RAY DIFFRACTION|2.3|Homo sapiens|0|SIGNALING PROTEIN","6XVB|Crystal structure of the kinase domain of human c-KIT with a cyclic imidate inhibitor covalently bound to Cys788|X-RAY DIFFRACTION|2.15|Homo sapiens|0|SIGNALING PROTEIN","7KHG|Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397|X-RAY DIFFRACTION|2.15|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","7KHJ|Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX8512 in the DFG-in state|X-RAY DIFFRACTION|2.8|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","7KHK|Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX9486 (bezuclastinib) in the DFG-in state|X-RAY DIFFRACTION|2.34|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","7ZW8|Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST|X-RAY DIFFRACTION|2.119|Homo sapiens|0|TRANSFERASE","7ZY6|Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST|X-RAY DIFFRACTION|3.09|Homo sapiens|0|TRANSFERASE","8DFM|Ectodomain of full-length wild-type KIT-SCF dimers|ELECTRON MICROSCOPY|3.45|Homo sapiens|0|TRANSFERASE","8DFP|Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers|ELECTRON MICROSCOPY|3.17|Homo sapiens|0|TRANSFERASE","8DFQ|Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers|ELECTRON MICROSCOPY|3.96|Homo sapiens|0|TRANSFERASE","8PQ9|c-KIT kinase domain in complex with avapritinib|X-RAY DIFFRACTION|1.7|Homo sapiens|0|TRANSFERASE","8PQA|c-KIT kinase domain in complex with avapritinib derivative 4|X-RAY DIFFRACTION|1.65|Homo sapiens|0|TRANSFERASE","8PQB|c-KIT kinase domain in complex with avapritinib derivative 8|X-RAY DIFFRACTION|1.87|Homo sapiens|0|TRANSFERASE","8PQC|c-KIT kinase domain in complex with avapritinib derivative 9|X-RAY DIFFRACTION|1.77|Homo sapiens|0|TRANSFERASE","8PQD|c-KIT kinase domain in complex with avapritinib derivative 10|X-RAY DIFFRACTION|1.5|Homo sapiens|0|TRANSFERASE","8PQE|c-KIT kinase domain in complex with avapritinib derivative 11|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","8PQF|c-KIT kinase domain in complex with avapritinib derivative 12|X-RAY DIFFRACTION|1.9|Homo sapiens|0|TRANSFERASE","8PQG|c-KIT T670I mutated kinase domain in complex with avapritinib|X-RAY DIFFRACTION|2.4|Homo sapiens|0|TRANSFERASE","8S13|apo c-KIT-wt kinase domain|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","8S14|c-KIT kinase domain in complex with sunitinib|X-RAY DIFFRACTION|1.5|Homo sapiens|0|TRANSFERASE","8S15|c-KIT kinase domain in complex with nintedanib|X-RAY DIFFRACTION|2.4|Homo sapiens|0|TRANSFERASE","8S16|c-KIT kinase domain in complex with imatinib|X-RAY DIFFRACTION|1.85|Homo sapiens|0|TRANSFERASE","8S17|c-KIT kinase domain in complex with ponatinib|X-RAY DIFFRACTION|2.2|Homo sapiens|0|TRANSFERASE","8S18|c-KIT kinase domain in complex with S116836|X-RAY DIFFRACTION|2.1|Homo sapiens|0|TRANSFERASE","8S19|c-KIT kinase domain in complex with staurosporine|X-RAY DIFFRACTION|2.3|Homo sapiens|0|TRANSFERASE","8S1A|c-KIT kinase domain in complex with crenolanib|X-RAY DIFFRACTION|1.85|Homo sapiens|0|TRANSFERASE","8S1B|c-KIT kinase domain in complex with IDRX-42 via soaking|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","9H71|KIT123-KITbp complex (Domains D1-3 of the human receptor tyrosine kinase KIT complexed with the de novo designed minibinder KITbp)|X-RAY DIFFRACTION|2.8|Homo sapiens; synthetic construct|0|PROTEIN BINDING"]}]}