{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":4,"total":55,"mapped":4},"pagination":{"has_next":false},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"P16473","source":"P16473|Thyrotropin receptor","targets":["2XWT|CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|SIGNALING PROTEIN/IMMUNE SYSTEM","3G04|Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody|X-RAY DIFFRACTION|2.55|Homo sapiens|0|IMMUNE SYSTEM","7T9I|Native human TSH bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)|ELECTRON MICROSCOPY|2.9|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","7T9M|Human Thyrotropin receptor bound by CS-17 Inverse Agonist Fab/Org 274179-0 Antagonist|ELECTRON MICROSCOPY|3.1|Homo sapiens; Mus musculus|0|MEMBRANE PROTEIN","7T9N|M22 Agonist Autoantibody bound to Human Thyrotropin receptor in complex with miniGs399 (composite structure)|ELECTRON MICROSCOPY|2.9|Homo sapiens|0|MEMBRANE PROTEIN","7UTZ|Human thyrotropin analog TR1402 bound to human Thyrotropin receptor in complex with miniGs399 (composite structure)|ELECTRON MICROSCOPY|2.4|Homo sapiens|0|MEMBRANE PROTEIN","7XW5|TSHR-thyroid stimulating hormone-Gs-ML109 complex|ELECTRON MICROSCOPY|2.96|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","7XW6|TSHR-Gs-M22 antibody-ML109 complex|ELECTRON MICROSCOPY|2.78|Homo sapiens; Mus musculus|0|MEMBRANE PROTEIN","7XW7|TSHR-K1-70 complex|ELECTRON MICROSCOPY|5.5|Homo sapiens|0|MEMBRANE PROTEIN"]},{"input":"P16410","source":"P16410|Cytotoxic T-lymphocyte protein 4","targets":["1AH1|CTLA-4, NMR, 20 STRUCTURES|SOLUTION NMR||Homo sapiens|0|IMMUNORECEPTOR","1H6E|MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH CTLA-4 INTERNALIZATION PEPTIDE TTGVYVKMPPT|X-RAY DIFFRACTION|3.6|HOMO SAPIENS; SYNTHETIC CONSTRUCT|0|ENDOCYTOSIS/EXOCYTOSIS","1I85|CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX|X-RAY DIFFRACTION|3.2|Homo sapiens|0|IMMUNE SYSTEM","1I8L|HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX|X-RAY DIFFRACTION|3|Homo sapiens|0|IMMUNE SYSTEM","2X44|Structure of a strand-swapped dimeric form of CTLA-4|X-RAY DIFFRACTION|2.6|HOMO SAPIENS|0|IMMUNE SYSTEM","3BX7|Engineered Human Lipocalin 2 (LCN2) in Complex with the Extracellular Domain of Human CTLA-4|X-RAY DIFFRACTION|2.1|Homo sapiens|0|DE NOVO PROTEIN, PROTEIN BINDING","3OSK|Crystal structure of human CTLA-4 apo homodimer|X-RAY DIFFRACTION|1.8|Homo sapiens|0|IMMUNE SYSTEM","5GGV|CTLA-4 in complex with tremelimumab Fab|X-RAY DIFFRACTION|1.998|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","5TRU|Structure of the first-in-class checkpoint inhibitor Ipilimumab bound to human CTLA-4|X-RAY DIFFRACTION|3|Homo sapiens|0|IMMUNE SYSTEM","5XJ3|Complex structure of ipilimumab-scFv and CTLA-4|X-RAY DIFFRACTION|3.2|Homo sapiens|0|IMMUNE SYSTEM","6RP8|Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution|X-RAY DIFFRACTION|2.6|Homo sapiens|0|IMMUNE SYSTEM","6RPJ|A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4|X-RAY DIFFRACTION|3.25|Camelus bactrianus; Homo sapiens|0|IMMUNE SYSTEM","6RQM|A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4|X-RAY DIFFRACTION|3|Camelus bactrianus; Homo sapiens|0|IMMUNE SYSTEM","6XY2|Crystal structure of CTLA-4 complexed with the Fab of HL32 antibody|X-RAY DIFFRACTION|3.05|Homo sapiens|0|IMMUNE SYSTEM","7CIO|Molecular interactions of cytoplasmic region of CTLA-4 with SH2 domains of PI3-kinase|X-RAY DIFFRACTION|1.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","7DV4|Crystal structure of anti-CTLA-4 VH domain in complex with human CTLA-4|X-RAY DIFFRACTION|2.38|Homo sapiens|0|IMMUNE SYSTEM","7ELX|The crystal structure of CTLA-4 and Fab|X-RAY DIFFRACTION|2.14|Homo sapiens|0|APOPTOSIS","7SU0|Crystal structure of an acidic pH-selective Ipilimumab variant Ipi.105 in complex with CTLA-4|X-RAY DIFFRACTION|2.41|Homo sapiens|0|IMMUNE SYSTEM","7SU1|Crystal structure of an acidic pH-selective Ipilimumab variant Ipi.106 in complex with CTLA-4|X-RAY DIFFRACTION|2.53|Homo sapiens|0|IMMUNE SYSTEM","8GAB|Crystal structure of CTLA-4 in complex with a high affinity CTLA-4 binder|X-RAY DIFFRACTION|2.72|Homo sapiens; synthetic construct|0|DE NOVO PROTEIN/Immune System","8HIT|Crystal structure of anti-CTLA-4 humanized IgG1 MAb--JS007 in complex with human CTLA-4|X-RAY DIFFRACTION|3.2|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM","9DQ3|Crystal structure of engineered Ipilimumab (mipi.4) Fab in complex with human CTLA-4|X-RAY DIFFRACTION|1.64|Homo sapiens|0|ANTITUMOR PROTEIN/IMMUNE SYSTEM"]},{"input":"Q9Y2R2","source":"Q9Y2R2|Tyrosine-protein phosphatase non-receptor type 22","targets":["2P6X|Crystal structure of human tyrosine phosphatase PTPN22|X-RAY DIFFRACTION|1.9|Homo sapiens|0|HYDROLASE","2QCJ|Native Structure of Lyp|X-RAY DIFFRACTION|3|Homo sapiens|0|HYDROLASE","2QCT|Structure of Lyp with inhibitor I-C11|X-RAY DIFFRACTION|2.8|Homo sapiens|0|HYDROLASE","3BRH|Protein Tyrosine Phosphatase PTPN-22 (Lyp) bound to the mono-Phosphorylated Lck active site peptide|X-RAY DIFFRACTION|2.2|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","3H2X|Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain|X-RAY DIFFRACTION|2.2|Homo sapiens|0|HYDROLASE","3OLR|PTPN22 in complex with consensus phospho-tyrosine peptide 1|X-RAY DIFFRACTION|2.5|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","3OMH|Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide|X-RAY DIFFRACTION|2.9|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","4J51|Cyrstal structure of protein tyrosine phosphatase Lyp catalytic domain complex with small molecular inhibitor L75N04|X-RAY DIFFRACTION|2.3|Homo sapiens|0|HYDROLASE/HYDROLASE INHIBITOR","7AAM|Crystal structure of the F-BAR domain of PSTIPIP1 bound to the CTH domain of the phosphatase LYP|X-RAY DIFFRACTION|2.15|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","9YDM|Targeting PTPN22 at non-orthosteric binding sites - a fragment approach|X-RAY DIFFRACTION|1.99|Homo sapiens|0|IMMUNE SYSTEM","9YG0|Targeting PTPN22 at non-orthosteric binding sites - a fragment approach|X-RAY DIFFRACTION|1.76|Homo sapiens|0|IMMUNE SYSTEM","9YG1|Targeting PTPN22 at non-orthosteric binding sites - a fragment approach|X-RAY DIFFRACTION|1.97|Homo sapiens|0|IMMUNE SYSTEM","9YG2|Targeting PTPN22 at non-orthosteric binding sites - a fragment approach|X-RAY DIFFRACTION|2.26|Homo sapiens|0|IMMUNE SYSTEM","9YG3|Targeting PTPN22 at non-orthosteric binding sites - a fragment approach|X-RAY DIFFRACTION|1.96|Homo sapiens|0|IMMUNE SYSTEM"]},{"input":"P01589","source":"P01589|Interleukin-2 receptor subunit alpha","targets":["1Z92|structure of interleukin-2 with its alpha receptor|X-RAY DIFFRACTION|2.8|Homo sapiens|0|IMMUNE SYSTEM","2B5I|cytokine receptor complex|X-RAY DIFFRACTION|2.3|Homo sapiens|0|CYTOKINE/CYTOKINE RECEPTOR","2ERJ|Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2|X-RAY DIFFRACTION|3|Homo sapiens|0|IMMUNE SYSTEM/CYTOKINE","3IU3|Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain|X-RAY DIFFRACTION|2.9|Homo sapiens; Mus musculus, Homo sapiens|0|IMMUNE SYSTEM","3NFP|Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain|X-RAY DIFFRACTION|2.86|Homo sapiens|0|Immune system/Cytokine","6VWU|X-ray structure of ALKS 4230, a fusion of circularly permuted human Interleukin-2 and Interleukin-2 Receptor alpha|X-RAY DIFFRACTION|3.4|Homo sapiens|0|CYTOKINE","6YIO|CRYSTAL STRUCTURE OF FAB RG6292 IN COMPLEX WITH CD25 ECD|X-RAY DIFFRACTION|1.83|Homo sapiens|0|IMMUNE SYSTEM","7F9W|CD25 in complex with Fab|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|ANTITUMOR PROTEIN","7ZMZ|Engineered Interleukin 2 bound to CD25 receptor|X-RAY DIFFRACTION|3.2|Homo sapiens|0|CYTOKINE","9KMC|Cryo-EM structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 and anti-CD25 Fab S417|ELECTRON MICROSCOPY|2.97|Homo sapiens; synthetic construct|0|IMMUNE SYSTEM"]}]}