{"context":{"query":">>uniprot>>reactome","source_dataset":"uniprot","target_dataset":"reactome"},"stats":{"queried":6,"total":46,"mapped":6},"pagination":{"has_next":false},"schema":"id|name|tax_id|is_disease_pathway","mappings":[{"input":"P29474","source":"P29474|Nitric oxide synthase 3","targets":["R-HSA-1222556|ROS and RNS production in phagocytes|9606|false","R-HSA-1474151|Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation|9606|false","R-HSA-203615|eNOS activation|9606|false","R-HSA-203641|NOSTRIN mediated eNOS trafficking|9606|false","R-HSA-203754|NOSIP mediated eNOS trafficking|9606|false","R-HSA-392154|Nitric oxide stimulates guanylate cyclase|9606|false","R-HSA-5218920|VEGFR2 mediated vascular permeability|9606|false","R-HSA-9009391|Extra-nuclear estrogen signaling|9606|false","R-HSA-9856530|High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells|9606|false"]},{"input":"Q01668","source":"Q01668|Voltage-dependent L-type calcium channel subunit alpha-1D","targets":["R-HSA-400042|Adrenaline,noradrenaline inhibits insulin secretion|9606|false","R-HSA-419037|NCAM1 interactions|9606|false","R-HSA-422356|Regulation of insulin secretion|9606|false","R-HSA-9662360|Sensory processing of sound by inner hair cells of the cochlea|9606|false"]},{"input":"P43220","source":"P43220|Glucagon-like peptide 1 receptor","targets":["R-HSA-381676|Glucagon-like Peptide-1 (GLP1) regulates insulin secretion|9606|false","R-HSA-418555|G alpha (s) signalling events|9606|false","R-HSA-420092|Glucagon-type ligand receptors|9606|false"]},{"input":"Q00534","source":"Q00534|Cyclin-dependent kinase 6","targets":["R-HSA-2559580|Oxidative Stress Induced Senescence|9606|false","R-HSA-2559582|Senescence-Associated Secretory Phenotype (SASP)|9606|false","R-HSA-2559585|Oncogene Induced Senescence|9606|false","R-HSA-69231|Cyclin D associated events in G1|9606|false","R-HSA-8934593|Regulation of RUNX1 Expression and Activity|9606|false","R-HSA-9630794|Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6|9606|true","R-HSA-9632700|Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6|9606|true","R-HSA-9661069|Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)|9606|true","R-HSA-9754119|Drug-mediated inhibition of CDK4/CDK6 activity|9606|false"]},{"input":"Q14432","source":"Q14432|cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A","targets":["R-HSA-418555|G alpha (s) signalling events|9606|false"]},{"input":"P17252","source":"P17252|Protein kinase C alpha type","targets":["R-HSA-111933|Calmodulin induced events|9606|false","R-HSA-114516|Disinhibition of SNARE formation|9606|false","R-HSA-1250196|SHC1 events in ERBB2 signaling|9606|false","R-HSA-1433557|Signaling by SCF-KIT|9606|false","R-HSA-1433559|Regulation of KIT signaling|9606|false","R-HSA-2179392|EGFR Transactivation by Gastrin|9606|false","R-HSA-2514859|Inactivation, recovery and regulation of the phototransduction cascade|9606|false","R-HSA-3000170|Syndecan interactions|9606|false","R-HSA-399997|Acetylcholine regulates insulin secretion|9606|false","R-HSA-4086398|Ca2+ pathway|9606|false","R-HSA-416993|Trafficking of GluR2-containing AMPA receptors|9606|false","R-HSA-418597|G alpha (z) signalling events|9606|false","R-HSA-4419969|Depolymerization of the Nuclear Lamina|9606|false","R-HSA-450520|HuR (ELAVL1) binds and stabilizes mRNA|9606|false","R-HSA-5099900|WNT5A-dependent internalization of FZD4|9606|false","R-HSA-5218921|VEGFR2 mediated cell proliferation|9606|false","R-HSA-5668599|RHO GTPases Activate NADPH Oxidases|9606|false","R-HSA-76005|Response to elevated platelet cytosolic Ca2+|9606|false","R-HSA-8853659|RET signaling|9606|false","R-HSA-9010642|ROBO receptors bind AKAP5|9606|false"]}]}