{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":6,"total":209,"mapped":6},"pagination":{"has_next":true,"next_token":"-1[]P29474,1,P29474,32,9]["},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"P29474","source":"P29474|Nitric oxide synthase 3","targets":["1M9J|human endothelial nitric oxide synthase with chlorzoxazone bound|X-RAY DIFFRACTION|2.43|Homo sapiens|0|OXIDOREDUCTASE","1M9K|Human Endothelial Nitric Oxide Synthase with 7-Nitroindazole Bound|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE","1M9M|human endothelial nitric oxide synthase with 6-nitroindazole bound|X-RAY DIFFRACTION|1.96|Homo sapiens|0|OXIDOREDUCTASE","1M9Q|human endothelial nitric oxide synthase with 5-nitroindazole bound|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE","1M9R|human endothelial nitric oxide synthase with 3-Bromo-7-Nitroindazole bound|X-RAY DIFFRACTION|2.56|Homo sapiens|0|OXIDOREDUCTASE","1NIW|Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin|X-RAY DIFFRACTION|2.05|Rattus norvegicus; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/OXIDOREDUCTASE","2LL7|Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide|SOLUTION NMR||Homo sapiens|0|OXIDOREDUCTASE","2MG5|Solution Structure of Calmodulin bound to the target peptide of Endothelial Nitrogen Oxide Synthase phosphorylated at Thr495|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|Metal binding protein/target peptide","2N8J|Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide Synthase Calmodulin Binding Domain Peptide at Physiological Calcium Concentration|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","3EAH|Structure of inhibited human eNOS oxygenase domain|X-RAY DIFFRACTION|2.44|Homo sapiens|0|OXIDOREDUCTASE","3NOS|HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE WITH ARGININE SUBSTRATE|X-RAY DIFFRACTION|2.4|Homo sapiens|0|OXIDOREDUCTASE","4D1O|Structure of human endothelial nitric oxide synthase heme domain with L-Arg bound|X-RAY DIFFRACTION|1.819|HOMO SAPIENS|0|OXIDOREDUCTASE","4D1P|Structure of human endothelial nitric oxide synthase heme domain IN COMPLEX WITH 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2-YL)METHOXY) METHYL)PYRROLIDIN-3-YL)OXY) METHYL)-4-METHYLPYRIDIN-2-AMINE|X-RAY DIFFRACTION|1.731|HOMO SAPIENS|0|OXIDOREDUCTASE","5UO8|Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile|X-RAY DIFFRACTION|2.18|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5UO9|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine|X-RAY DIFFRACTION|2.19|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOA|Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOB|Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile|X-RAY DIFFRACTION|2.292|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOC|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5VVB|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5VVC|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile|X-RAY DIFFRACTION|2.4|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5VVD|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)benzonitrile|X-RAY DIFFRACTION|2.25|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5XOF|Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I|X-RAY DIFFRACTION|1.963|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6AV6|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-Fluoro-5-(3-(methylamino)propyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.08|Homo sapiens|0|OXIDOREDUCTASE","6AV7|Structure of human endothelial nitric oxide synthase heme domain in complex with HW69|X-RAY DIFFRACTION|1.916|Homo sapiens|0|OXIDOREDUCTASE","6CIE|Structure of human endothelial nitric oxide synthase heme domain in complex with N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquino-lin-6-yl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE","6CIF|Structure of the human endothelial nitric oxide synthase heme domain in complex with N-(1-(Piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","6NH1|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.216|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH2|Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.29|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH3|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH4|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.27|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH5|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.959|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH6|Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.189|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH7|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH8|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NHF|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.83|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6POU|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(4-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.194|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POV|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.047|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POW|Structure of human endotheial nitric oxide synthase heme domain in complex with 7-(5-(Aminomethyl)pyridin-3-yl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POX|Structure of human endothelialnitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-ethoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.197|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POY|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-propoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.3|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POZ|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-isopropoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP0|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(cyclobutylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.97|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP1|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(cyclopropylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.76|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP2|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-((4-(2-Amino-4-methylquinolin-7-yl)-2-(aminomethyl)phenoxy)methyl)benzonitrile|X-RAY DIFFRACTION|2.02|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP3|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-2-ylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP4|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-3-ylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","7M56|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine|X-RAY DIFFRACTION|1.957|Homo sapiens|0|OXIDOREDUCTASE","7TSG|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(dimethylamino)propyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.85|Homo sapiens|0|OXIDOREDUCTASE","7TSH|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)propyl)pyridin-2-amine|X-RAY DIFFRACTION|2.145|Homo sapiens|0|OXIDOREDUCTASE","7TSI|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE","7TSK|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine|X-RAY DIFFRACTION|2.049|Homo sapiens|0|OXIDOREDUCTASE","7TSL|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)propyl)pyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","7TSM|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)prop-1-yn-1-yl)pyridin-2-amine bishydrochloride|X-RAY DIFFRACTION|1.85|Homo sapiens|0|OXIDOREDUCTASE","7TSN|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.08|Homo sapiens|0|OXIDOREDUCTASE","7TSO|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)propyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","7TSP|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(4,4-difluoropiperidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","7UAO|Structure of human endothelial nitric oxide synthase heme domain in complex with (6-(3-(4,4-difluoropiperidin-1-yl)propyl)-4-methylpyridin-2-amine)|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","8FGN|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","8FGO|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.799|Homo sapiens|0|OXIDOREDUCTASE","8FGP|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methoxypyridin-2-amine|X-RAY DIFFRACTION|1.88|Homo sapiens|0|OXIDOREDUCTASE","8FGQ|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-6-methylpyrimidin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","8FGR|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-aminoethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.98|Homo sapiens|0|OXIDOREDUCTASE","8FGS|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(diethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8449|Homo sapiens|0|OXIDOREDUCTASE","8FGT|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(2,3-difluoro-5-(2-(4-methylpiperazin-1-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","8FGU|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(difluoromethyl)-6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","8UFR|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.871|Homo sapiens|0|OXIDOREDUCTASE","8UFS|Structure of human endothelial nitric oxide synthase E361Q mutant heme domain obtain after soaking crystal with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","8UFT|Structure of human endothelial nitric oxide synthase P370N mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine|X-RAY DIFFRACTION|1.78|Homo sapiens|0|OXIDOREDUCTASE","8UFU|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(9-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","9CW2|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW4|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(3-fluoro-5-((methylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW5|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-6-(3-((methylamino)methyl)-5-(trifluoromethyl)phenyl)pyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.88|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW6|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(3-chloro-5-((dimethylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.151|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW7|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-5'-((methylamino)methyl)-[2,3'-bipyridin]-6-amine dihydrochloride|X-RAY DIFFRACTION|1.83|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW8|Structure of human endothelial nitric oxide synthase heme domain bound with 3-(6-amino-4-methylpyridin-2-yl)-5-((methylamino)methyl)benzonitrile dihydrochloride|X-RAY DIFFRACTION|1.92|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW9|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(2,3-difluoro-5-((methylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.12|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWD|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((dimethylamino)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.92|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWI|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((3,3-difluoroazetidin-1-yl)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.73|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWJ|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((4,4-difluoropiperidin-1-yl)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWK|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(2,3-difluoro-5-(2-(methylamino)ethyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9C1Z|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(((4-(6-aminopyridin-2-yl)butyl)amino)methyl)phenoxy)methyl)quinolin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","9MWN|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","9MWO|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.76|Homo sapiens|0|OXIDOREDUCTASE","9MWP|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(furan-3-carboximidamido)benzyl)amino)ethyl)phenyl)furan-3-carboximidamide|X-RAY DIFFRACTION|1.86|Homo sapiens|0|OXIDOREDUCTASE","9MWQ|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(isoxazole-3-carboximidamido)benzyl)amino)ethyl)phenyl)isoxazole-3-carboximidamide|X-RAY DIFFRACTION|1.938|Homo sapiens|0|OXIDOREDUCTASE","9MWR|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiazole-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-2-carboximidamide|X-RAY DIFFRACTION|1.97|Homo sapiens|0|OXIDOREDUCTASE","9MWS|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(2-((3-(thiazole-5-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.899|Homo sapiens|0|OXIDOREDUCTASE","9MWT|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(2-((3-(furan-2-carboximidamido)benzyl)amino)ethyl)phenyl)furan-2-carboximidamide|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","9MWU|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)furan-2-carboximidamide|X-RAY DIFFRACTION|1.736|Homo sapiens|0|OXIDOREDUCTASE","9MWV|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.896|Homo sapiens|0|OXIDOREDUCTASE","9MWW|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE","9MWX|Structure of human endothelial nitric oxide synthase heme domain bound withN-(4-(2-((3-(thiazole-5-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.839|Homo sapiens|0|OXIDOREDUCTASE","9MZ1|Structure of human endothelial nitric oxide synthase heme domain bound with 7-(3-aminomethyl)phenyl-6-fluoro-4-methylquinoin-2-amine|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","9MZ2|Structure of human endothelial nitric oxide synthase heme domain bound with 2-(2-amino-6-fluoro-4-methylquinolin-7-yl)-5-(aminomethyl)phenol|X-RAY DIFFRACTION|1.99|Homo sapiens|0|OXIDOREDUCTASE","9MZ3|Structure of human endothelial nitric oxide synthase heme domain bound 2-(2-amino-6-fluoro-4-methylquinolin-7-yl)-5-(2-aminoethyl)phenol|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE","9MZ4|Structure of human endothelial nitric oxide synthase heme domain bound 7-(3-(aminomethyl)-4-(cyclopropylmethoxy)phenyl)-6-fluoro-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.94|Homo sapiens|0|OXIDOREDUCTASE","9Q4X|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(dimethylamino)ethyl)-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q4Y|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((2,3-difluoro-5-(2-(methylamino)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q4Z|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(ethyl(methyl)amino)ethyl)-2,3-difluorophenxy)methyl)-4-methylphridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q51|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(diethylamino)ethyl)-2,3-difluorophenxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR"]},{"input":"Q01668","source":"Q01668|Voltage-dependent L-type calcium channel subunit alpha-1D","targets":["3LV3|Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent calcium channel alpha1 subunit (residues 513-521)|X-RAY DIFFRACTION|1.94|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","7UHF|Human L-type voltage-gated calcium channel Cav1.3 in the presence of cinnarizine at 3.1 Angstrom resolution|ELECTRON MICROSCOPY|3.1|Homo sapiens|0|TRANSPORT PROTEIN","7UHG|Human L-type voltage-gated calcium channel Cav1.3 at 3.0 Angstrom resolution|ELECTRON MICROSCOPY|3.0|Homo sapiens|0|TRANSPORT PROTEIN","8E59|Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone at 3.1 Angstrom resolution|ELECTRON MICROSCOPY|3.1|Homo sapiens|0|TRANSPORT PROTEIN","8E5A|Human L-type voltage-gated calcium channel Cav1.3 treated with 1.4 mM Sofosbuvir at 3.3 Angstrom resolution|ELECTRON MICROSCOPY|3.3|Homo sapiens|0|TRANSPORT PROTEIN","8E5B|Human L-type voltage-gated calcium channel Cav1.3 in the presence of Amiodarone and Sofosbuvir at 3.3 Angstrom resolution|ELECTRON MICROSCOPY|3.3|Homo sapiens|0|TRANSPORT PROTEIN"]},{"input":"P43220","source":"P43220|Glucagon-like peptide 1 receptor","targets":["3C59|Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain|X-RAY DIFFRACTION|2.3|Homo sapiens; SYNTHETIC CONSTRUCT|0|Signaling protein/Signaling protein","3C5T|Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|Signaling protein/Signaling protein","3IOL|Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/SIGNALING PROTEIN","4ZGM|Crystal structure of Semaglutide peptide backbone in complex with the GLP-1 receptor extracellular domain|X-RAY DIFFRACTION|1.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5E94|Antibody-bound Glucagon-like Peptide-1 receptor extracellular domain|X-RAY DIFFRACTION|2|Homo sapiens; Mus musculus|0|MEMBRANE PROTEIN","5NX2|Crystal structure of thermostabilised full-length GLP-1R in complex with a truncated peptide agonist at 3.7 A resolution|X-RAY DIFFRACTION|3.7|Homo sapiens; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","5OTT|Extracellular domain of GLP-1 receptor in complex with exendin-4 variant Gly2Hcs/Thr5Hcs|X-RAY DIFFRACTION|1.92|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5OTU|Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Hcs|X-RAY DIFFRACTION|1.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5OTV|Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cyc/Thr11Hcs|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5OTW|Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Hcs/Thr11Cys|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5OTX|Extracellular domain of GLP-1 receptor in complex with GLP-1 variant Ala8Cys/Thr11Cys|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","5VEW|Structure of the human GLP-1 receptor complex with PF-06372222|X-RAY DIFFRACTION|2.7|Enterobacteria phage T4; Homo sapiens|0|SIGNALING PROTEIN","5VEX|Structure of the human GLP-1 receptor complex with NNC0640|X-RAY DIFFRACTION|3|Enterobacteria phage T4; Homo sapiens|0|SIGNALING PROTEIN","6B3J|3.3 angstrom phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex|ELECTRON MICROSCOPY|3.3|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","6GB1|Crystal structure of the GLP1 receptor ECD with Peptide 11|X-RAY DIFFRACTION|2.73|Homo sapiens; SYNTHETIC CONSTRUCT|0|PEPTIDE BINDING PROTEIN","6KJV|Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain|X-RAY DIFFRACTION|2.8|Enterobacteria phage T4; Homo sapiens|0|SIGNALING PROTEIN","6KK1|Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain|X-RAY DIFFRACTION|2.8|Enterobacteria phage T4; Homo sapiens|0|SIGNALING PROTEIN","6KK7|Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain|X-RAY DIFFRACTION|3.1|Enterobacteria phage T4; Homo sapiens|0|SIGNALING PROTEIN","6LN2|Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38)|X-RAY DIFFRACTION|3.2|Clostridium pasteurianum; Homo sapiens; Mus musculus|0|MEMBRANE PROTEIN","6ORV|Non-peptide agonist (TT-OAD2) bound to the Glucagon-Like peptide-1 (GLP-1) Receptor|ELECTRON MICROSCOPY|3.0|Homo sapiens|0|MEMBRANE PROTEIN","6VCB|Cryo-EM structure of the Glucagon-like peptide-1 receptor in complex with G protein, GLP-1 peptide and a positive allosteric modulator|ELECTRON MICROSCOPY|3.3|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/MEMBRANE PROTEIN","6X18|GLP-1 peptide hormone bound to Glucagon-Like peptide-1 (GLP-1) Receptor|ELECTRON MICROSCOPY|2.1|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","6X19|Non peptide agonist CHU-128, bound to Glucagon-Like peptide-1 (GLP-1) Receptor|ELECTRON MICROSCOPY|2.1|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","6X1A|Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor|ELECTRON MICROSCOPY|2.5|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","6XOX|cryo-EM of human GLP-1R bound to non-peptide agonist LY3502970|ELECTRON MICROSCOPY|3.1|Homo sapiens; Lama glama; Mus musculus|0|MEMBRANE PROTEIN","7C2E|GLP-1R-Gs complex structure with a small molecule full agonist|ELECTRON MICROSCOPY|4.2|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","7DUQ|Cryo-EM structure of the compound 2 and GLP-1-bound human GLP-1 receptor-Gs complex|ELECTRON MICROSCOPY|2.5|Bos taurus; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|BIOSYNTHETIC PROTEIN","7DUR|Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex|ELECTRON MICROSCOPY|3.3|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|BIOSYNTHETIC PROTEIN","7E14|Compound2_GLP-1R_OWL833_Gs complex structure|ELECTRON MICROSCOPY|2.9|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|MEMBRANE PROTEIN","7EVM|Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex|ELECTRON MICROSCOPY|2.5|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|STRUCTURAL PROTEIN","7FIM|Cryo-EM structure of the tirzepatide (LY3298176)-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|3.4|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","7KI0|Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein|ELECTRON MICROSCOPY|2.5|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","7KI1|Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein|ELECTRON MICROSCOPY|2.5|Homo sapiens; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","7LCI|PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex|ELECTRON MICROSCOPY|2.9|Homo sapiens|0|MEMBRANE PROTEIN","7LCJ|PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex|ELECTRON MICROSCOPY|2.82|Homo sapiens|0|MEMBRANE PROTEIN","7LCK|PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R)|ELECTRON MICROSCOPY|3.24|Homo sapiens|0|MEMBRANE PROTEIN","7LLL|Exendin-4-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein|ELECTRON MICROSCOPY|3.7|Heloderma suspectum; Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","7LLY|Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein|ELECTRON MICROSCOPY|3.3|Homo sapiens; Lama glama; Sus scrofa|0|MEMBRANE PROTEIN","7RG9|cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form|ELECTRON MICROSCOPY|3.2|Homo sapiens; Lama glama; Mus musculus|0|MEMBRANE PROTEIN","7RGP|cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R bound to tirzepatide|ELECTRON MICROSCOPY|2.9|Homo sapiens; Lama glama; Mus musculus; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","7RTB|Peptide-19 bound to the Glucagon-Like Peptide-1 Receptor (GLP-1R)|ELECTRON MICROSCOPY|2.14|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","7S15|GLP-1 receptor bound with Pfizer small molecule agonist|ELECTRON MICROSCOPY|3.8|Homo sapiens|0|MEMBRANE PROTEIN","7S1M|Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 1)|ELECTRON MICROSCOPY|2.41|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","7S3I|Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 2)|ELECTRON MICROSCOPY|2.51|Homo sapiens|0|MEMBRANE PROTEIN","7VBH|Cryo-EM structure of the GIPR/GLP-1R/GCGR triagonist peptide 20-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|3.0|Bos taurus; Escherichia coli; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","7VBI|Cryo-EM structure of the non-acylated tirzepatide (LY3298176)-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|3.0|Bos taurus; Escherichia coli; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","7X8R|Cryo-EM structure of the Boc5-bound hGLP-1R-Gs complex|ELECTRON MICROSCOPY|2.61|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|MEMBRANE PROTEIN","7X8S|Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex|ELECTRON MICROSCOPY|3.09|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|MEMBRANE PROTEIN","8JIP|Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|2.85|Bos taurus; Escherichia coli; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","8JIR|Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|2.57|Bos taurus; Escherichia coli; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","8JIS|Cryo-EM structure of the GLP-1R/GCGR dual agonist peptide15-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|2.46|Bos taurus; Escherichia coli; Homo sapiens; Rattus norvegicus; SYNTHETIC CONSTRUCT|0|STRUCTURAL PROTEIN","8WG7|Cryo-EM structures of peptide free and Gs-coupled GLP-1R|ELECTRON MICROSCOPY|2.54|Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct|0|MEMBRANE PROTEIN","8YW3|Cryo-EM structure of the retatrutide-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|2.68|Homo sapiens; synthetic construct|0|STRUCTURAL PROTEIN","8YWF|Cryo-EM structure of GLP1 complex bound with Retatrutide|ELECTRON MICROSCOPY|2.74|Homo sapiens|0|MEMBRANE PROTEIN","9BYO|Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-asp3|ELECTRON MICROSCOPY|2.31|Homo sapiens; Lama glama; synthetic construct|0|MEMBRANE PROTEIN","9C0K|Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-phe1|ELECTRON MICROSCOPY|2.72|Homo sapiens; Lama glama; synthetic construct|0|MEMBRANE PROTEIN","9E2A|Glucagon Like Peptide Receptor-1 (GLP1R) A316T mutant with GLP-1 peptide. Dominant negative Gs complex.|ELECTRON MICROSCOPY|3.3|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","9EBN|Peptide 1 (GLP-1 (Aib16, ACPC18)) bound to GLP-1R/Gs complex|ELECTRON MICROSCOPY|3.44|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","9EBO|Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 1)|ELECTRON MICROSCOPY|3.13|Homo sapiens; Lama glama; SYNTHETIC CONSTRUCT|0|MEMBRANE PROTEIN","9EBQ|Peptide 2 (GLP-1 (ACPC18)) bound to GLP-1R/Gs complex (conformer 2)|ELECTRON MICROSCOPY|3.16|Homo sapiens; Lama glama|0|MEMBRANE PROTEIN","9IVG|Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|3.0|Homo sapiens|0|MEMBRANE PROTEIN","9IVM|Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex in the presence of LSN3318839|ELECTRON MICROSCOPY|3.22|Homo sapiens|0|MEMBRANE PROTEIN","9J1P|Cryo-EM structure of the g1:Ox-bound human GLP-1R-Gs complex|ELECTRON MICROSCOPY|2.99|Bos taurus; Homo sapiens; Lama glama; Rattus norvegicus; synthetic construct|0|MEMBRANE PROTEIN"]},{"input":"Q00534","source":"Q00534|Cyclin-dependent kinase 6","targets":["1BI7|MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURE OF THE CDK6-P16INK4A TUMOR SUPPRESSOR COMPLEX|X-RAY DIFFRACTION|3.4|Homo sapiens|0|COMPLEX (KINASE/ANTI-ONCOGENE)","1BI8|MECHANISM OF G1 CYCLIN DEPENDENT KINASE INHIBITION FROM THE STRUCTURES CDK6-P19INK4D INHIBITOR COMPLEX|X-RAY DIFFRACTION|2.8|Homo sapiens|0|COMPLEX (KINASE/INHIBITOR)","1BLX|P19INK4D/CDK6 COMPLEX|X-RAY DIFFRACTION|1.9|Homo sapiens; Mus musculus|0|COMPLEX (INHIBITOR PROTEIN/KINASE)","1G3N|STRUCTURE OF A P18(INK4C)-CDK6-K-CYCLIN TERNARY COMPLEX|X-RAY DIFFRACTION|2.9|Homo sapiens; Human herpesvirus 8|0|cell cycle, signaling protein","1JOW|Crystal structure of a complex of human CDK6 and a viral cyclin|X-RAY DIFFRACTION|3.1|Homo sapiens; Saimiriine herpesvirus 2|0|CELL CYCLE/TRANSFERASE","1XO2|Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin|X-RAY DIFFRACTION|2.9|Homo sapiens; Saimiriine herpesvirus 2|0|CELL CYCLE/TRANSFERASE","2EUF|X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991|X-RAY DIFFRACTION|3|Herpesvirus saimiri (strain 11); Homo sapiens|0|CELL CYCLE/TRANSFERASE","2F2C|X-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanol|X-RAY DIFFRACTION|2.8|Herpesvirus saimiri (strain 11); Homo sapiens|0|CELL CYCLE/TRANSFERASE","3NUP|CDK6 (monomeric) in complex with inhibitor|X-RAY DIFFRACTION|2.6|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","3NUX|CDK6 (monomeric) in complex with inhibitor|X-RAY DIFFRACTION|2.7|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4AUA|Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6)|X-RAY DIFFRACTION|2.31|HOMO SAPIENS|0|TRANSFERASE","4EZ5|CDK6 (monomeric) in complex with inhibitor|X-RAY DIFFRACTION|2.7|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4TTH|Crystal structure of a CDK6/Vcyclin complex with inhibitor bound|X-RAY DIFFRACTION|2.9|Homo sapiens; Saimiriine herpesvirus 2|0|TRANSFERASE/CELL CYCLE/INHIBITOR","5L2I|The X-ray co-crystal structure of human CDK6 and Palbociclib.|X-RAY DIFFRACTION|2.75|Homo sapiens|0|Transferase/Transferase Inhibitor","5L2S|The X-ray co-crystal structure of human CDK6 and Abemaciclib.|X-RAY DIFFRACTION|2.27|Homo sapiens|0|Transferase/Transferase Inhibitor","5L2T|The X-ray co-crystal structure of human CDK6 and Ribociclib.|X-RAY DIFFRACTION|2.37|Homo sapiens|0|Transferase/Transferase Inhibitor","6OQL|CDK6 in complex with Cpd13 (R)-5-fluoro-4-(4-methyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a]azepin-3-yl)-N-(5-(4-methylpiperazin-1-yl)pyridin-2-yl)pyrimidin-2-amine|X-RAY DIFFRACTION|2.707|Homo sapiens|0|TRANSFERASE/TRANSFERASE inhibitor","6OQO|CDK6 in complex with Cpd24 N-(5-(6-ethyl-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-2-yl)-5-fluoro-4-(4-methyl-5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a]azepin-3-yl)pyrimidin-2-amine|X-RAY DIFFRACTION|1.977|Homo sapiens|0|TRANSFERASE/TRANSFERASE inhibitor","8I0M|Structure of CDK6 in complex with inhibitor|X-RAY DIFFRACTION|2.7772|Homo sapiens|0|CELL CYCLE/INHIBITOR","9D8U|Crystal structure of CDK6 in complex with atirmociclib|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","9PE7|CDK6 to CDK4 active site surrogate in complex with compound 6|X-RAY DIFFRACTION|2.05|Homo sapiens|0|TRANSFERASE/INHIBITOR","9PE8|CDK6 to CDK4 active site surrogate in complex with PF-07220060|X-RAY DIFFRACTION|1.8|Homo sapiens|0|TRANSFERASE/INHIBITOR"]},{"input":"Q14432","source":"Q14432|cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A","targets":["7EG0|Cryo-EM structure of anagrelide-induced PDE3A-SLFN12 complex|ELECTRON MICROSCOPY|3.4|Homo sapiens|0|APOPTOSIS","7EG1|Cryo-EM structure of DNMDP-induced PDE3A-SLFN12 complex|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|APOPTOSIS","7EG4|Cryo-EM structure of nauclefine-induced PDE3A-SLFN12 complex|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|APOPTOSIS","7KWE|Crystal structure of the catalytic domain of human PDE3A bound to DNMDP|X-RAY DIFFRACTION|2|Homo sapiens|0|HYDROLASE","7L27|Crystal structure of the catalytic domain of human PDE3A|X-RAY DIFFRACTION|1.7|Homo sapiens|0|HYDROLASE","7L28|Crystal structure of the catalytic domain of human PDE3A bound to Trequinsin|X-RAY DIFFRACTION|2.2|Homo sapiens|0|HYDROLASE/HYDROLASE INHIBITOR","7L29|Crystal structure of the catalytic domain of human PDE3A bound to AMP|X-RAY DIFFRACTION|2.08|Homo sapiens|0|HYDROLASE","7LRC|Cryo-EM of the SLFN12-PDE3A complex: PDE3A body refinement|ELECTRON MICROSCOPY|2.97|Homo sapiens|0|HYDROLASE","7LRD|Cryo-EM of the SLFN12-PDE3A complex: Consensus subset model|ELECTRON MICROSCOPY|3.22|Homo sapiens|0|RNA BINDING PROTEIN"]},{"input":"Q13557","source":"Q13557|Calcium/calmodulin-dependent protein kinase type II subunit delta","targets":["2VN9|Crystal Structure of Human Calcium Calmodulin dependent Protein Kinase II delta isoform 1, CAMKD|X-RAY DIFFRACTION|2.3|Homo sapiens|0|TRANSFERASE","2W2C|STRUCTURE OF THE TETRADECAMERIC OLIGOMERISATION DOMAIN OF CALCIUM- CALMODULIN DEPENDENT PROTEIN KINASE II DELTA|X-RAY DIFFRACTION|2.7|HOMO SAPIENS|0|TRANSFERASE","2WEL|Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","3GP2|Calmodulin bound to peptide from calmodulin kinase II (CaMKII)|X-RAY DIFFRACTION|1.46|Gallus gallus; SYNTHETIC CONSTRUCT|0|metal binding protein/Transferase","5VLO|The structure of human CamKII with bound inhibitor|X-RAY DIFFRACTION|2.05|Homo sapiens|0|TRANSFERASE","6AYW|The structure of human CamKII with bound inhibitor|X-RAY DIFFRACTION|2.05|Homo sapiens|0|TRANSFERASE/TRANSFERASE Inhibitor","7ZRP|2.65 Angstrom crystal structure of Ca/CaM:CaMKIIdelta peptide complex|X-RAY DIFFRACTION|2.65|Homo sapiens; SYNTHETIC CONSTRUCT|0|METAL BINDING PROTEIN","7ZRQ|1.68 Angstrom crystal structure of Ca/CaM-E140G:CaMKIIdelta peptide complex|X-RAY DIFFRACTION|1.68|Homo sapiens; SYNTHETIC CONSTRUCT|0|METAL BINDING PROTEIN","9BLH|Crystal structure of calcium/calmodulin-dependent protein kinase type II subunit delta complexed with ribociclib|X-RAY DIFFRACTION|2.35|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR"]}]}