{"context":{"query":">>uniprot>>signor","source_dataset":"uniprot","target_dataset":"signor"},"stats":{"queried":1,"total":83,"mapped":1},"pagination":{"has_next":false},"schema":"id|entity_a|entity_b|effect|mechanism|direct","mappings":[{"input":"P38398","source":"P38398|Breast cancer type 1 susceptibility protein","targets":["SIGNOR-106432|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-106436|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-106440|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-120575|CHEK2|BRCA1|up-regulates|phosphorylation|false","SIGNOR-123065|AURKA|BRCA1|up-regulates|phosphorylation|false","SIGNOR-142888|BRCA1|CDKN1B|\"up-regulates quantity by expression\"|\"transcriptional regulation\"|false","SIGNOR-147711|BRCA1|RBBP8|up-regulates|ubiquitination|false","SIGNOR-153450|CDK4|BRCA1|down-regulates|phosphorylation|false","SIGNOR-154312|AKT1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-155144|ABRAXAS1|BRCA1|up-regulates|binding|false","SIGNOR-155201|UIMC1|BRCA1|up-regulates|binding|false","SIGNOR-162499|BARD1|BRCA1|up-regulates|binding|false","SIGNOR-163472|AKT1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-187591|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-187595|CDK1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-187599|CDK1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-187603|CDK1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-187607|CDK2|BRCA1|up-regulates|phosphorylation|false","SIGNOR-198467|BRCA1|ATM|\"up-regulates quantity by expression\"|\"transcriptional regulation\"|false","SIGNOR-201050|ATR|BRCA1|up-regulates|phosphorylation|false","SIGNOR-216984|CyclinD/CDK4|BRCA1|down-regulates|phosphorylation|false","SIGNOR-244164|AKT|BRCA1|up-regulates|phosphorylation|false","SIGNOR-244168|AKT|BRCA1|up-regulates|phosphorylation|false","SIGNOR-244487|PALB2|BRCA1|\"up-regulates activity\"|binding|false","SIGNOR-248560|PPP1CA|BRCA1|\"down-regulates activity\"|dephosphorylation|false","SIGNOR-248561|PPP1CA|BRCA1|\"down-regulates activity\"|dephosphorylation|false","SIGNOR-248562|PPP1CA|BRCA1|\"down-regulates activity\"|dephosphorylation|false","SIGNOR-250581|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-250582|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-250583|ATR|BRCA1|\"up-regulates activity\"|phosphorylation|false","SIGNOR-253759|BRCA1|CTSD|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-253760|BRCA1|FOXC2|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-253761|BRCA1|HSPA5|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-253762|BRCA1|RNASEL|\"up-regulates quantity by expression\"|\"transcriptional regulation\"|false","SIGNOR-253937|BRCA1|TFF1|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-253974|BRCA1|ESR1|\"down-regulates activity\"||false","SIGNOR-256326|CASP3|BRCA1|\"down-regulates quantity by destabilization\"|cleavage|false","SIGNOR-256432|\"Caspase 3 complex\"|BRCA1|\"down-regulates quantity by destabilization\"|cleavage|false","SIGNOR-259185|BRIP1|BRCA1|\"up-regulates activity\"|binding|false","SIGNOR-259194|CTBP1|BRCA1|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-259196|CTBP1|BRCA1|\"down-regulates quantity by repression\"|\"transcriptional regulation\"|false","SIGNOR-263236|BRCA1|FANCD2|\"up-regulates activity\"|ubiquitination|false","SIGNOR-266698|HDLBP|BRCA1|\"up-regulates activity\"|binding|false","SIGNOR-271105|Ub:E2|BRCA1|\"up-regulates activity\"|ubiquitination|false","SIGNOR-272754|BRCA1|ERCC6|\"down-regulates quantity by destabilization\"|polyubiquitination|false","SIGNOR-275454|FRK|BRCA1|\"up-regulates quantity by stabilization\"|phosphorylation|false","SIGNOR-277353|BRCA1|TOP1|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-278583|HUWE1|BRCA1|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-278623|BRCA1|CDC25C|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-278624|BRCA1|SAFB|\"up-regulates quantity by stabilization\"|ubiquitination|false","SIGNOR-278745|BRCA1|NSD2|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-278752|BRCA1|MACROH2A1|\"up-regulates activity\"|ubiquitination|false","SIGNOR-278813|HERC2|BRCA1|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-69701|RAD50|BRCA1|up-regulates|binding|false","SIGNOR-72048|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72052|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72056|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72060|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72064|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72068|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72072|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72075|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72079|ATM|BRCA1|unknown|phosphorylation|false","SIGNOR-72083|CDK1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72087|CDK1|BRCA1|up-regulates|phosphorylation|false","SIGNOR-72091|CDK2|BRCA1|up-regulates|phosphorylation|false","SIGNOR-87845|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-91482|ATM|BRCA1|up-regulates|phosphorylation|false","SIGNOR-252435|BRCA1|AKT1|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-252458|BRCA1|AKT|\"down-regulates quantity by destabilization\"|ubiquitination|false","SIGNOR-250832|CSNK2A1|BRCA1|unknown|phosphorylation|false","SIGNOR-251055|CSNK2B|BRCA1|unknown|phosphorylation|false","SIGNOR-251499|BRCA1|Cell_cycle_block|up-regulates||false","SIGNOR-251500|BRCA1|DNA_repair|up-regulates||false","SIGNOR-251501|BRCA1|MRE11/RAD50/NBS1|\"up-regulates activity\"|binding|false","SIGNOR-253936|ASPM|BRCA1|\"up-regulates quantity by expression\"|\"transcriptional regulation\"|false","SIGNOR-263203|RBBP8|BRCA1|\"up-regulates activity\"|relocalization|false","SIGNOR-263224|BRCA1|\"BRCA1-BARD1 complex\"|\"form complex\"|binding|false","SIGNOR-263271|\"Fanconi anemia ID complex\"|BRCA1|up-regulates||false","SIGNOR-267282|BRCA1|Cell_cycle_progress|down-regulates||false","SIGNOR-267474|BRCA1|ACACA|\"down-regulates activity\"|binding|false","SIGNOR-272037|FBXO44|BRCA1|\"down-regulates quantity by destabilization\"|binding|false","SIGNOR-272039|\"Cullin 1-RBX1-Skp1\"|BRCA1|\"down-regulates quantity by destabilization\"|polyubiquitination|false"]}]}