{"context":{"query":">>uniprot>>signor","source_dataset":"uniprot","target_dataset":"signor"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]P40763,1,P40763,126,4]["},"schema":"id|entity_a|entity_b|effect|mechanism|direct|score","mappings":[{"input":"P40763","source":"P40763|Signal transducer and activator of transcription 3","targets":["SIGNOR-101251|RPS6KA5|STAT3|up-regulates|phosphorylation|true|0.39","SIGNOR-118596|MAPK3|STAT3|up-regulates|phosphorylation|true|0.72","SIGNOR-118600|MAPK3|STAT3|up-regulates|phosphorylation|true|0.72","SIGNOR-121965|EGFR|STAT3|up-regulates activity|phosphorylation|true|0.88","SIGNOR-122085|ALK|STAT3|up-regulates|binding|true|0.44","SIGNOR-124325|CDK5|STAT3|up-regulates|phosphorylation|true|0.40","SIGNOR-124723|PIAS3|STAT3|down-regulates|sumoylation|true|0.73","SIGNOR-129685|IRAK1|STAT3|up-regulates|phosphorylation|true|0.55","SIGNOR-133379|IL21R|STAT3|up-regulates||false|0.61","SIGNOR-135211|PTPN1|STAT3|down-regulates|dephosphorylation|true|0.55","SIGNOR-139460|ALK|STAT3|up-regulates|binding|true|0.44","SIGNOR-143828|PRKCD|STAT3|up-regulates|phosphorylation|true|0.60","SIGNOR-143832|PRKCE|STAT3|up-regulates|phosphorylation|true|0.40","SIGNOR-146915|MTOR|STAT3|up-regulates|phosphorylation|true|0.75","SIGNOR-154783|MAPK14|STAT3|up-regulates|phosphorylation|true|0.62","SIGNOR-155828|NLK|STAT3|up-regulates|phosphorylation|true|0.35","SIGNOR-161439|MTOR|STAT3|up-regulates|phosphorylation|true|0.75","SIGNOR-166664|RPS6KA5|STAT3|up-regulates|phosphorylation|true|0.39","SIGNOR-178699|PTPN6|STAT3|down-regulates|dephosphorylation|true|0.46","SIGNOR-179275|MAPK9|STAT3|up-regulates|phosphorylation|true|0.48","SIGNOR-179912|MAPK14|STAT3|up-regulates|phosphorylation|true|0.62","SIGNOR-185933|PTPRD|STAT3|down-regulates|dephosphorylation|true|0.52","SIGNOR-187775|JAK1|STAT3|up-regulates activity|phosphorylation|true|0.80","SIGNOR-187779|MAPK3|STAT3|up-regulates|phosphorylation|true|0.72","SIGNOR-187787|MAPK3|STAT3|up-regulates|phosphorylation|true|0.72","SIGNOR-187793|STAT3|SP1/STAT3|form complex|binding|true|0.46","SIGNOR-194847|S3I-201|STAT3|down-regulates|chemical inhibition|true|0.80","SIGNOR-195766|PKM|STAT3|up-regulates|phosphorylation|true|0.44","SIGNOR-235445|SRC|STAT3|up-regulates activity|phosphorylation|true|0.79","SIGNOR-235664|STAT3|STAT1/STAT3|form complex|binding|true|0.61","SIGNOR-235692|EGFR|STAT3|up-regulates activity|phosphorylation|true|0.88","SIGNOR-235704|MAPK8|STAT3|up-regulates activity|phosphorylation|true|0.57","SIGNOR-236346|MAP3K1|STAT3|up-regulates activity|phosphorylation|true|0.29","SIGNOR-236369|JAK1|STAT3|up-regulates activity|binding|true|0.80","SIGNOR-236463|JAK2|STAT3|up-regulates activity|phosphorylation|true|0.82","SIGNOR-238549|5,15-Diphenyl-21H,23H-porphine|STAT3|down-regulates activity|chemical inhibition|true|0.80","SIGNOR-238638|JAK2|STAT3|up-regulates activity|phosphorylation|true|0.82","SIGNOR-238648|PIAS3|STAT3|down-regulates activity|binding|true|0.73","SIGNOR-245048|STAT3|Proliferation|up-regulates||false|0.70","SIGNOR-247341|SRC|STAT3|up-regulates activity|phosphorylation|true|0.79","SIGNOR-248427|PTPN1|STAT3|down-regulates activity|dephosphorylation|true|0.55","SIGNOR-248442|PTPRD|STAT3|down-regulates activity|dephosphorylation|true|0.52","SIGNOR-248563|PPP1CA|STAT3|down-regulates activity|dephosphorylation|true|0.33","SIGNOR-248719|PTPRR|STAT3|down-regulates activity|dephosphorylation|true|0.20","SIGNOR-249450|MAPK3|STAT3|up-regulates activity|phosphorylation|true|0.72","SIGNOR-249546|JAK1|STAT3|up-regulates activity|phosphorylation|true|0.80","SIGNOR-249547|STAT3|M2_polarization|up-regulates||false|0.70","SIGNOR-249556|PPARG|STAT3|down-regulates||false|0.38","SIGNOR-249567|SOCS3|STAT3|down-regulates||false|0.71","SIGNOR-251139|FGFR3|STAT3|up-regulates activity|phosphorylation|true|0.63","SIGNOR-251142|FGFR4|STAT3|up-regulates activity|phosphorylation|true|0.40","SIGNOR-251267|HCK|STAT3|up-regulates activity|phosphorylation|true|0.62","SIGNOR-251742|STAT3|HGF|up-regulates quantity by expression|transcriptional regulation|true|0.62","SIGNOR-252090|STAT3|Cell_growth|up-regulates||false|0.70","SIGNOR-253049|STAT3|CCND1|up-regulates quantity by expression|transcriptional regulation|false|0.79","SIGNOR-253050|STAT3|SOCS3|up-regulates quantity by expression|transcriptional regulation|false|0.71","SIGNOR-253583|STAT3|SOCS3|up-regulates quantity by expression|transcriptional regulation|true|0.71","SIGNOR-253590|JAK1|STAT3|up-regulates activity|phosphorylation|true|0.80","SIGNOR-254246|HIC1|STAT3|down-regulates quantity by repression|binding|true|0.37","SIGNOR-254303|STAT3|RORC|up-regulates||false|0.64","SIGNOR-254304|STAT3|FOXP3|down-regulates||false|0.57","SIGNOR-254364|STAT3|FOXP3|down-regulates||false|0.57","SIGNOR-254515|STAT3|IL10|up-regulates|transcriptional regulation|false|0.79","SIGNOR-254517|STAT3|TGFB1|up-regulates|transcriptional regulation|false|0.63","SIGNOR-254729|PTPRG|STAT3|up-regulates activity|dephosphorylation|true|0.26","SIGNOR-254761|DAB2IP|STAT3|down-regulates activity|binding|true|0.35","SIGNOR-254762|STAT3|BIRC5|up-regulates quantity by expression|transcriptional regulation|false|0.63","SIGNOR-254795|STAT3|IL1RN|up-regulates quantity by expression|transcriptional regulation|false|0.51","SIGNOR-255024|STAT3|SMAD2/STAT3/EP300|form complex|binding|true|0.57","SIGNOR-255036|SMAD3/PIAS3|STAT3|down-regulates||true|0.63","SIGNOR-255234|STAT3|KRT17|up-regulates quantity by expression|transcriptional regulation|false|0.26","SIGNOR-255238|STAT3|CD46|up-regulates quantity by expression|transcriptional regulation|false|0.27","SIGNOR-255239|STAT3|HAMP|up-regulates quantity by expression|transcriptional regulation|false|0.43","SIGNOR-255240|STAT3|HSPA1A|up-regulates quantity by expression|transcriptional regulation|false|0.32","SIGNOR-255241|STAT3|HSPA1B|up-regulates quantity by expression|transcriptional regulation|false|0.20","SIGNOR-255244|STAT3|SALL4|up-regulates quantity by expression|transcriptional regulation|false|0.58","SIGNOR-255330|SOCS3|STAT3|down-regulates activity||false|0.71","SIGNOR-255331|STAT3|FBXO32|up-regulates quantity by expression|transcriptional regulation|false|0.28","SIGNOR-255333|STAT3|CEBPD|up-regulates quantity by expression|transcriptional regulation|false|0.61","SIGNOR-255334|STAT3|CEBPD|up-regulates quantity by expression|transcriptional regulation|false|0.61","SIGNOR-255335|STAT3|CASP3|up-regulates quantity by expression|transcriptional regulation|false|0.46","SIGNOR-255411|STAT3|CCND1|up-regulates quantity by expression|transcriptional regulation|false|0.79","SIGNOR-255413|STAT3|MYC|up-regulates quantity by expression||false|0.75","SIGNOR-255415|IL6|STAT3|up-regulates activity||false|0.76","SIGNOR-255416|STAT3|MYOD1|up-regulates quantity by expression|transcriptional regulation|false|0.52","SIGNOR-255632|STAT3|Proliferation|up-regulates||false|0.70","SIGNOR-256234|STAT3|IL10|up-regulates|transcriptional regulation|false|0.79","SIGNOR-256254|JAK3|STAT3|up-regulates|phosphorylation|true|0.79","SIGNOR-256255|TYK2|STAT3|up-regulates|phosphorylation|true|0.69","SIGNOR-256256|STAT3|Proliferation|up-regulates||false|0.70","SIGNOR-256257|STAT3|Fibrosis|up-regulates||false|0.70","SIGNOR-259188|STAT3|CD274|up-regulates quantity by expression|transcriptional regulation|true|0.46","SIGNOR-259203|EML4-ALK|STAT3|up-regulates activity|phosphorylation|true|0.20","SIGNOR-259456|STAT3|VEGFA|up-regulates quantity by expression|transcriptional regulation|true|0.79","SIGNOR-260406|STC2|STAT3|up-regulates||false|0.20","SIGNOR-260654|MFGE8|STAT3|up-regulates activity||false|0.28","SIGNOR-260917|RET/PTC2|STAT3|up-regulates activity|phosphorylation|true|0.20","SIGNOR-261931|STAT3|S100A9|up-regulates quantity by expression|transcriptional regulation|false|0.37","SIGNOR-263492|LEPR|STAT3|up-regulates activity|phosphorylation|true|0.76","SIGNOR-263495|LEPR|STAT3|up-regulates activity|binding|true|0.76"]}]}