{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":1,"total":100,"mapped":1},"pagination":{"has_next":true,"next_token":"-1[]Q00987,1,Q00987,56,5]["},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"Q00987","source":"Q00987|E3 ubiquitin-protein ligase Mdm2","targets":["1RV1|CRYSTAL STRUCTURE OF HUMAN MDM2 WITH AN IMIDAZOLINE INHIBITOR|X-RAY DIFFRACTION|2.3|Homo sapiens|0|LIGASE","1T4E|Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor|X-RAY DIFFRACTION|2.6|Homo sapiens|0|LIGASE","1T4F|Structure of human MDM2 in complex with an optimized p53 peptide|X-RAY DIFFRACTION|1.9|Homo sapiens|0|LIGASE","1YCR|MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53|X-RAY DIFFRACTION|2.6|Homo sapiens|0|COMPLEX (ONCOGENE PROTEIN/PEPTIDE)","1Z1M|NMR structure of unliganded MDM2|SOLUTION NMR||Homo sapiens|0|LIGASE","2AXI|HDM2 in complex with a beta-hairpin|X-RAY DIFFRACTION|1.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE/LIGASE INHIBITOR","2C6A|Solution structure of the C4 zinc-finger domain of HDM2|SOLUTION NMR||HOMO SAPIENS|0|LIGASE","2C6B|Solution structure of the C4 zinc-finger domain of HDM2|SOLUTION NMR||HOMO SAPIENS|0|LIGASE","2FOP|The Crystal Structure of the N-terminal domain of HAUSP/USP7 complexed with mdm2 peptide 147-150|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","2GV2|MDM2 in complex with an 8-mer p53 peptide analogue|X-RAY DIFFRACTION|1.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","2HDP|Solution Structure of Hdm2 RING Finger Domain|SOLUTION NMR||Homo sapiens|0|LIGASE","2LZG|NMR Structure of Mdm2 (6-125) with Pip-1|SOLUTION NMR||Homo sapiens|0|PROTEIN BINDING","2M86|Solution structure of Hdm2 with engineered cyclotide|SOLUTION NMR||Homo sapiens; synthetic construct|0|PROTEIN BINDING/SIGNALING PROTEIN","2MPS|Structure of complex of MDM2(3-109) and P73 TAD(10-25)|SOLUTION NMR||Homo sapiens|0|LIGASE/PEPTIDE","2RUH|Chemical Shift Assignments for MIP and MDM2 in bound state|SOLUTION NMR||Homo sapiens|0|PEPTIDE BINDING PROTEIN","2VJE|Crystal Structure of the MDM2-MDMX RING Domain Heterodimer|X-RAY DIFFRACTION|2.2|HOMO SAPIENS|0|LIGASE","2VJF|Crystal Structure of the MDM2-MDMX RING Domain Heterodimer|X-RAY DIFFRACTION|2.3|HOMO SAPIENS|0|LIGASE","3EQS|Crystal structure of human MDM2 in complex with a 12-mer peptide inhibitor|X-RAY DIFFRACTION|1.65||0|LIGASE","3G03|Structure of human MDM2 in complex with high affinity peptide|X-RAY DIFFRACTION|1.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|CELL CYCLE","2F1Y|Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide|X-RAY DIFFRACTION|1.7|Homo sapiens|0|HYDROLASE","3IUX|Crystal structure of human MDM2 in complex with a potent miniature protein inhibitor (18-residues)|X-RAY DIFFRACTION|1.65||0|LIGASE","3IWY|Crystal structure of human MDM2 complexed with D-peptide (12 residues)|X-RAY DIFFRACTION|1.93||0|LIGASE/LIGASE INHIBITOR","3JZK|crystal structure of MDM2 with chromenotriazolopyrimidine 1|X-RAY DIFFRACTION|2.1|Homo sapiens|0|LIGASE","3JZR|Human MDM2 liganded with a 12mer peptide inhibitor (pDI6W)|X-RAY DIFFRACTION|2.1|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","3JZS|Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ)|X-RAY DIFFRACTION|1.78|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","3LBK|Structure of human MDM2 protein in complex with a small molecule inhibitor|X-RAY DIFFRACTION|2.3|Homo sapiens|0|LIGASE","3LBL|Structure of human MDM2 protein in complex with Mi-63-analog|X-RAY DIFFRACTION|1.6|Homo sapiens|0|LIGASE","3LNJ|Crystal structure of human MDM2 in complex with D-peptide inhibitor (DPMI-alpha)|X-RAY DIFFRACTION|2.4||0|LIGASE/LIGASE INHIBITOR","3LNZ|Crystal structure of human MDM2 with a 12-mer peptide inhibitor PMI (N8A mutant)|X-RAY DIFFRACTION|1.95||0|LIGASE/LIGASE INHIBITOR","3MQS|Crystal Structure of the USP7:Hdm2(PSTS) complex|X-RAY DIFFRACTION|2.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","3TJ2|Structure of a novel submicromolar MDM2 inhibitor|X-RAY DIFFRACTION|2.1|Homo sapiens|0|PROTEIN BINDING/INHIBITOR","3TPX|Crystal structure of human MDM2 in complex with a trifluoromethylated D-peptide inhibitor|X-RAY DIFFRACTION|1.8||0|LIGASE/LIGASE INHIBITOR","3TU1|Exhaustive Fluorine Scanning towards Potent p53-MDM2 Antagonist|X-RAY DIFFRACTION|1.603|Homo sapiens|0|LIGASE","3V3B|Structure of the Stapled p53 Peptide Bound to Mdm2|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|ligase/ligase inhibitor","3VBG|Structure of hDM2 with Dimer Inducing Indolyl Hydantoin RO-2443|X-RAY DIFFRACTION|2.8|Homo sapiens|0|Ligase/ligase activator","3VZV|Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor|X-RAY DIFFRACTION|2.8|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","3W69|Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor|X-RAY DIFFRACTION|1.9|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4DIJ|The Central Valine Concept Provides an Entry in a New Class of Non Peptide Inhibitors of the P53-MDM2 Interaction|X-RAY DIFFRACTION|1.9|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4ERE|crystal structure of MDM2 (17-111) in complex with compound 23|X-RAY DIFFRACTION|1.8|Homo sapiens|0|Ligase/Ligase inhibitor","4ERF|crystal structure of MDM2 (17-111) in complex with compound 29 (AM-8553)|X-RAY DIFFRACTION|2|Homo sapiens|0|Ligase/Ligase inhibitor","4HBM|Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors|X-RAY DIFFRACTION|1.9|Homo sapiens|0|ligase/ligase inhibitor","4HFZ|Crystal Structure of an MDM2/P53 Peptide Complex|X-RAY DIFFRACTION|2.694|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","4HG7|Crystal Structure of an MDM2/Nutlin-3a complex|X-RAY DIFFRACTION|1.6|Homo sapiens|0|LIGASE","4JV7|Co-crystal structure of MDM2 with inhibitor (2S,5R,6S)-2-benzyl-5,6-bis(4-bromophenyl)-4-methylmorpholin-3-one|X-RAY DIFFRACTION|2.2|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4JV9|Co-crystal structure of MDM2 with inhibitor (2S,5R,6S)-2-benzyl-5,6-bis(4-chlorophenyl)-4-methylmorpholin-3-one|X-RAY DIFFRACTION|2.5|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4JVE|Co-crystal structure of MDM2 with inhibitor (2R,3E)-2-[(2S,3R,6S)-2,3-bis(4-chlorophenyl)-6-(4-fluorobenzyl)-5-oxomorpholin-4-yl]pent-3-enoic acid|X-RAY DIFFRACTION|2.3|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4JVR|Co-crystal structure of MDM2 with inhibitor (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide|X-RAY DIFFRACTION|1.7|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4JWR|Co-crystal structure of MDM2 with inhibitor {(2S,5R,6S)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-[(2S)-1-hydroxybutan-2-yl]-3-oxomorpholin-2-yl}acetic acid|X-RAY DIFFRACTION|2.35|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4MDN|Structure of a novel submicromolar MDM2 inhibitor|X-RAY DIFFRACTION|1.905|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4MDQ|Structure of a novel submicromolar MDM2 inhibitor|X-RAY DIFFRACTION|2.119|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4OAS|co-crystal structure of MDM2 (17-111) in complex with compound 25|X-RAY DIFFRACTION|1.7|Homo sapiens|0|ligase/ligase inhibitor","4OBA|Co-crystal structure of MDM2 with Inhibitor Compound 4|X-RAY DIFFRACTION|1.602|Homo sapiens|0|ligase/ligase inhibitor","4OCC|co-crystal structure of MDM2(17-111) in complex with compound 48|X-RAY DIFFRACTION|1.8|Homo sapiens|0|ligase/ligase inhibitor","4ODE|Co-Crystal Structure of MDM2 with Inhibitor Compound 4|X-RAY DIFFRACTION|1.8|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4ODF|Co-Crystal Structure of MDM2 with Inhibitor Compound 47|X-RAY DIFFRACTION|2.2006|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4OGN|Co-Crystal Structure of MDM2 with Inhbitor Compound 3|X-RAY DIFFRACTION|1.377|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4OGT|Co-Crystal Structure of MDM2 with Inhbitor Compound 46|X-RAY DIFFRACTION|1.5361|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4OGV|Co-Crystal Structure of MDM2 with Inhibitor Compound 49|X-RAY DIFFRACTION|2.197|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4OQ3|Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction|X-RAY DIFFRACTION|2.3|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4QO4|co-crystal structure of MDM2 (17-111) with compound 16, {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-(6-CYCLOPROPYLPYRIDIN-2-YL)PROPYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID|X-RAY DIFFRACTION|1.7|Homo sapiens|0|Ligase/Ligase inhibitor","4QOC|crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID|X-RAY DIFFRACTION|1.7|Homo sapiens|0|Ligase/Ligase inhibitor","4UD7|Structure of the stapled peptide YS-02 bound to MDM2|X-RAY DIFFRACTION|1.6|HOMO SAPIENS; SYNTHETIC CONSTRUCT|0|LYASE","4UE1|Structure of the stapled peptide YS-01 bound to MDM2|X-RAY DIFFRACTION|1.45|HOMO SAPIENS; SYNTHETIC CONSTRUCT|0|LIGASE/PEPTIDE","4UMN|Structure of a stapled peptide antagonist bound to Nutlin-resistant Mdm2.|X-RAY DIFFRACTION|1.99|Homo sapiens; SYNTHETIC CONSTRUCT|0|CELL CYCLE","4WT2|Co-crystal Structure of MDM2 in Complex with AM-7209|X-RAY DIFFRACTION|1.42|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","4XXB|Crystal structure of human MDM2-RPL11|X-RAY DIFFRACTION|2.4|Homo sapiens|0|RNA BINDING PROTEIN/METAL BINDING PROTEIN","4ZFI|Structure of Mdm2 with low molecular weight inhibitor|X-RAY DIFFRACTION|2|Homo sapiens|0|LIGASE","4ZGK|Structure of Mdm2 with low molecular weight inhibitor.|X-RAY DIFFRACTION|2|Homo sapiens|0|LIGASE","4ZYC|Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode: Hdm2 (MDM2) complexed with cpd5|X-RAY DIFFRACTION|1.95|Homo sapiens|0|LIGASE","4ZYF|Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with NVP-CGM097|X-RAY DIFFRACTION|1.8|Homo sapiens|0|CELL CYCLE","4ZYI|Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with cpd2|X-RAY DIFFRACTION|1.67|Homo sapiens|0|CELL CYCLE","5AFG|Structure of the Stapled Peptide Bound to Mdm2|X-RAY DIFFRACTION|1.9|HOMO SAPIENS; SYNTHETIC CONSTRUCT|0|LIGASE","5C5A|Crystal Structure of HDM2 in complex with Nutlin-3a|X-RAY DIFFRACTION|1.146|Homo sapiens|0|LIGASE","5HMH|HDM2 in complex with a 3,3-Disubstituted Piperidine|X-RAY DIFFRACTION|1.79|Homo sapiens|0|ligase/ligase inhibitor","5HMI|HDM2 in complex with a 3,3-Disubstituted Piperidine|X-RAY DIFFRACTION|1.74|Homo sapiens|0|ligase/ligase inhibitor","5HMK|HDM2 in complex with a 3,3-Disubstituted Piperidine|X-RAY DIFFRACTION|2.17|Homo sapiens|0|ligase/ligase inhibitor","5J7F|Structure of MDM2 with low molecular weight inhibitor with aliphatic linker.|X-RAY DIFFRACTION|2|Homo sapiens|0|LIGASE","5J7G|Structure of MDM2 with low molecular weight inhibitor with aliphatic linker.|X-RAY DIFFRACTION|1.85|Homo sapiens|0|LIGASE","5LAV|Novel Spiro[3H-indole-3,2 -pyrrolidin]-2(1H)-one Inhibitors of the MDM2-p53 Interaction: HDM2 (MDM2) in complex with compound 6b|X-RAY DIFFRACTION|1.73|Homo sapiens|0|LIGASE","5LAW|Novel Spiro[3H-indole-3,2 -pyrrolidin]-2(1H)-one Inhibitors of the MDM2-p53 Interaction: HDM2 (MDM2) IN COMPLEX WITH COMPOUND 14|X-RAY DIFFRACTION|1.64|Homo sapiens|0|LIGASE","5LAY|Discovery of New Natural-product-inspired Spiro-oxindole Compounds as Orally Active Inhibitors of the MDM2-p53 Interaction: HDM2 (MDM2) IN COMPLEX WITH COMPOUND 6g|X-RAY DIFFRACTION|2.71|Homo sapiens|0|LIGASE","5LAZ|Novel Spiro[3H-indole-3,2 -pyrrolidin]-2(1H)-one Inhibitors of the MDM2-p53 Interaction: HDM2 (MDM2) IN COMPLEX WITH COMPOUND BI-0252|X-RAY DIFFRACTION|1.66|Homo sapiens|0|LIGASE","5LN2|Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument|X-RAY DIFFRACTION|1.58|Homo sapiens|0|CELL CYCLE","5MNJ|Structure of MDM2-MDMX-UbcH5B-ubiquitin complex|X-RAY DIFFRACTION|2.16|Homo sapiens|0|LIGASE","5OAI|Structure of MDM2 with low molecular weight inhibitor|X-RAY DIFFRACTION|2|Homo sapiens|0|LIGASE","5OC8|HDM2 (17-111, WILD TYPE) COMPLEXED WITH NVP-HDM201 AT 1.56A|X-RAY DIFFRACTION|1.56|Homo sapiens|0|LIGASE","5SWK|Crystal structure of p53 epitope-scaffold based on a inhibitor of cysteine proteases in complex with human MDM2|X-RAY DIFFRACTION|1.923|Entamoeba histolytica; Homo sapiens|0|DE NOVO PROTEIN","5TRF|MDM2 in complex with SAR405838|X-RAY DIFFRACTION|2.1|Homo sapiens|0|LIGASE/LIGASE INHIBITOR","5UMM|CRYSTAL STRUCTURE OF HUMAN MDM2 IN COMPLEX WITH 12-MER PEPTIDE INHIBITOR M3|X-RAY DIFFRACTION|1.65||0|TRANSFERASE/TRANSFERASE INHIBITOR","5VK0|Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI|X-RAY DIFFRACTION|1.8||0|LIGASE/LIGASE INHIBITOR","5WTS|Green fluorescent protein linked MTide-02 inhibitor in complex with mdm2|X-RAY DIFFRACTION|3.004|Aequorea victoria; Camelus dromedarius; Homo sapiens|0|FLUORESCENT PROTEIN/INHIBITOR","5XXK|Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids|X-RAY DIFFRACTION|1.66|Homo sapiens; SYNTHETIC CONSTRUCT|0|ONCOPROTEIN/INHIBITOR","5Z02|Crystal structure of HIS6-tagged Mdm2 with nutlin-3a|X-RAY DIFFRACTION|1.35|Homo sapiens|0|ONCOPROTEIN","5ZXF|The 1.25A Crystal structure of His6-tagged Mdm2 in complex with nutlin-3a|X-RAY DIFFRACTION|1.25|Homo sapiens|0|CELL CYCLE","6AAW|Mdm2 in complex with a D amino Acid Containing Stapled Peptide|X-RAY DIFFRACTION|2|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","6GGN|In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor|X-RAY DIFFRACTION|2|Homo sapiens|0|CELL CYCLE","6H22|Crystal structure of Mdm2 bound to a stapled peptide|X-RAY DIFFRACTION|2.006|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIGASE","6HFA|Crystal structure of hDM2 in complex with a C-terminal triurea capped peptide chimera foldamer.|X-RAY DIFFRACTION|1.79|Homo sapiens; SYNTHETIC CONSTRUCT|0|ONCOPROTEIN","6I29|X-ray structure of the p53-MDM2 inhibitor NMI801 bound to HDM2 at 2.1A resolution|X-RAY DIFFRACTION|2.1|Homo Sapiens|0|LIGASE","6I3S|Crystal structure of MDM2 in complex with compound 13.|X-RAY DIFFRACTION|1.77|Homo sapiens|0|LIGASE"]}]}