{"context":{"query":">>uniprot>>string","source_dataset":"uniprot","target_dataset":"string"},"stats":{"queried":6,"total":6,"mapped":6},"pagination":{"has_next":false},"schema":"id|preferred_name|protein_size|interaction_count|annotation","mappings":[{"input":"Q13315","source":"Q13315|Serine-protein kinase ATM","targets":["9606.ENSP00000278616|ATM|3056|6446|Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospec [...] "]},{"input":"P07288","source":"P07288|Prostate-specific antigen","targets":["9606.ENSP00000314151|KLK3|261|2776|Prostate-specific antigen; Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum."]},{"input":"O14746","source":"O14746|Telomerase reverse transcriptase","targets":["9606.ENSP00000309572|TERT|1132|5450|Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] "]},{"input":"Q8IWU2","source":"Q8IWU2|Serine/threonine-protein kinase LMTK2","targets":["9606.ENSP00000297293|LMTK2|1503|806|Serine/threonine-protein kinase LMTK2; Phosphorylates PPP1C, phosphorylase b and CFTR; Belongs to the protein kinase superfamily. Tyr protein kinase family."]},{"input":"P23229","source":"P23229|Integrin alpha-6","targets":["9606.ENSP00000386896|ITGA6|1091|2768|Integrin alpha-6 heavy chain; Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds t [...] "]},{"input":"O75751","source":"O75751|Solute carrier family 22 member 3","targets":["9606.ENSP00000275300|SLC22A3|556|1398|Solute carrier family 22 member 3; Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family."]}]}