{"context":{"query":">>uniprot>>reactome","source_dataset":"uniprot","target_dataset":"reactome"},"stats":{"queried":1,"total":22,"mapped":1},"pagination":{"has_next":false},"schema":"id|name|tax_id|is_disease_pathway","mappings":[{"input":"Q14790","source":"Q14790|Caspase-8","targets":["R-HSA-111465|Apoptotic cleavage of cellular proteins|9606|false","R-HSA-140534|Caspase activation via Death Receptors in the presence of ligand|9606|false","R-HSA-168638|NOD1/2 Signaling Pathway|9606|false","R-HSA-2562578|TRIF-mediated programmed cell death|9606|false","R-HSA-264870|Caspase-mediated cleavage of cytoskeletal proteins|9606|false","R-HSA-3371378|Regulation by c-FLIP|9606|false","R-HSA-5213460|RIPK1-mediated regulated necrosis|9606|false","R-HSA-5218900|CASP8 activity is inhibited|9606|false","R-HSA-5357786|TNFR1-induced proapoptotic signaling|9606|false","R-HSA-5357905|Regulation of TNFR1 signaling|9606|false","R-HSA-5660668|CLEC7A/inflammasome pathway|9606|false","R-HSA-5675482|Regulation of necroptotic cell death|9606|false","R-HSA-69416|Dimerization of procaspase-8|9606|false","R-HSA-75108|Activation, myristolyation of BID and translocation to mitochondria|9606|false","R-HSA-75153|Apoptotic execution phase|9606|false","R-HSA-75157|FasL/ CD95L signaling|9606|false","R-HSA-75158|TRAIL  signaling|9606|false","R-HSA-9013957|TLR3-mediated TICAM1-dependent programmed cell death|9606|false","R-HSA-933543|NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10|9606|false","R-HSA-9686347|Microbial modulation of RIPK1-mediated regulated necrosis|9606|true","R-HSA-9693928|Defective RIPK1-mediated regulated necrosis|9606|true","R-HSA-9758274|Regulation of NF-kappa B signaling|9606|false"]}]}