{"context":{"query":">>uniprot>>signor","source_dataset":"uniprot","target_dataset":"signor"},"stats":{"queried":1,"total":53,"mapped":1},"pagination":{"has_next":false},"schema":"id|entity_a|entity_b|effect|mechanism|direct|score","mappings":[{"input":"Q5S007","source":"Q5S007|Leucine-rich repeat serine/threonine-protein kinase 2","targets":["SIGNOR-154498|LRRK2|MSN|up-regulates activity|phosphorylation|true|0.55","SIGNOR-166466|LRRK2|LRRK2|up-regulates|phosphorylation|true|0.20","SIGNOR-166470|LRRK2|LRRK2|up-regulates|phosphorylation|true|0.20","SIGNOR-166474|LRRK2|LRRK2|up-regulates|phosphorylation|true|0.20","SIGNOR-169217|ARHGEF7|LRRK2|up-regulates|binding|true|0.46","SIGNOR-169221|LRRK2|ARHGEF7|up-regulates|phosphorylation|true|0.46","SIGNOR-169225|LRRK2|ARHGEF7|up-regulates|phosphorylation|true|0.46","SIGNOR-174044|LRRK2|AKT1|up-regulates|phosphorylation|true|0.38","SIGNOR-188417|LRRK2|LRRK2|up-regulates|phosphorylation|true|0.20","SIGNOR-188421|LRRK2|LRRK2|up-regulates|phosphorylation|true|0.20","SIGNOR-188425|LRRK2|LRRK2|down-regulates|phosphorylation|true|0.20","SIGNOR-188429|LRRK2|LRRK2|unknown|phosphorylation|true|0.20","SIGNOR-188433|LRRK2|LRRK2|unknown|phosphorylation|true|0.20","SIGNOR-188437|LRRK2|LRRK2|unknown|phosphorylation|true|0.20","SIGNOR-192068|LRRK2|SH3GL1|down-regulates|phosphorylation|true|0.47","SIGNOR-192072|LRRK2|SH3GL2|down-regulates|phosphorylation|true|0.47","SIGNOR-192075|LRRK2|SH3GL2|down-regulates|phosphorylation|true|0.47","SIGNOR-195756|LRRK2|MAPT|down-regulates|phosphorylation|true|0.53","SIGNOR-196264|ARFGAP1|LRRK2|up-regulates|binding|true|0.58","SIGNOR-196267|LRRK2|ARFGAP1|down-regulates|phosphorylation|true|0.58","SIGNOR-196732|LRRK2|ARFGAP1|down-regulates|phosphorylation|true|0.58","SIGNOR-202187|LRRK2|DVL3|up-regulates|binding|true|0.48","SIGNOR-202436|LRRK2|SNAPIN|down-regulates|phosphorylation|true|0.51","SIGNOR-205115|LRRK2|AKT|up-regulates|phosphorylation|true|0.38","SIGNOR-237005|LRRK2|Autophagy|up-regulates||false|0.70","SIGNOR-237444|PRKACA|LRRK2|down-regulates activity|phosphorylation|true|0.41","SIGNOR-244410|LRRK2|AKT|up-regulates|phosphorylation|true|0.38","SIGNOR-249690|LRRK2|SNCA|down-regulates activity|phosphorylation|true|0.62","SIGNOR-252598|LRRK2|AKT1|up-regulates|phosphorylation|true|0.38","SIGNOR-260267|LRRK2|Rab8a|up-regulates activity|phosphorylation|true|0.33","SIGNOR-261277|LRRK2|Rab10|down-regulates activity|phosphorylation|true|0.33","SIGNOR-262891|LRRK2|Prdx3|down-regulates activity|phosphorylation|true|0.41","SIGNOR-268928|LRRK2||up-regulates quantity|transcriptional regulation|false|0.29","SIGNOR-276495|LRRK2|DNM1L|up-regulates activity|phosphorylation|true|0.57","SIGNOR-276873|LRRK2|RAB5B|up-regulates activity|phosphorylation|true|0.60","SIGNOR-277196|LRRK2|NSF|up-regulates activity|phosphorylation|true|0.37","SIGNOR-277251|LRRK2|MAP3K5|up-regulates activity|phosphorylation|true|0.33","SIGNOR-277417|LRRK2|Lars|down-regulates activity|phosphorylation|true|0.20","SIGNOR-278183|LRRK2|AP2M1|up-regulates activity|phosphorylation|true|0.26","SIGNOR-278281|LRRK2|PTK2|down-regulates activity|phosphorylation|true|0.20","SIGNOR-278340|LRRK2|RCAN1|up-regulates activity|phosphorylation|true|0.37","SIGNOR-278615|STUB1|LRRK2|down-regulates quantity by destabilization|ubiquitination|true|0.43","SIGNOR-278763|MID2|LRRK2|down-regulates quantity by destabilization|ubiquitination|true|0.20","SIGNOR-278953|LRRK2|RIPK2|up-regulates activity|phosphorylation|true|0.38","SIGNOR-279057|LRRK2|MAP2K3|up-regulates activity|phosphorylation|true|0.39","SIGNOR-279058|LRRK2|Rps15|up-regulates activity|phosphorylation|true|0.48","SIGNOR-279202|LRRK2|EZR|up-regulates activity|phosphorylation|true|0.41","SIGNOR-279203|LRRK2|RDX|up-regulates activity|phosphorylation|true|0.36","SIGNOR-279338|LRRK2|Nlrc4|up-regulates activity|phosphorylation|true|0.36","SIGNOR-279474|LRRK2|Rab29|up-regulates activity|phosphorylation|true|0.58","SIGNOR-279475|LRRK2|Rab29|up-regulates activity|phosphorylation|true|0.58","SIGNOR-279531|LRRK2|BCL2|up-regulates activity|phosphorylation|true|0.33","SIGNOR-39433|LRRK2|MSN|up-regulates activity|phosphorylation|true|0.55"]}]}