{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":6,"total":253,"mapped":6},"pagination":{"has_next":true,"next_token":"-1[]P29474,1,P29474,32,9]["},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"Q8NBP7","source":"Q8NBP7|Proprotein convertase subtilisin/kexin type 9","targets":["2P4E|Crystal Structure of PCSK9|X-RAY DIFFRACTION|1.98|Homo sapiens|0|HYDROLASE","2PMW|The Crystal Structure of Proprotein convertase subtilisin kexin type 9 (PCSK9)|X-RAY DIFFRACTION|2.3|Homo sapiens|0|HYDROLASE","2QTW|The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain|X-RAY DIFFRACTION|1.9|Homo sapiens|0|HYDROLASE","2W2M|WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR|X-RAY DIFFRACTION|2.4|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2N|WT PCSK9-deltaC bound to EGF-A H306Y mutant of LDLR|X-RAY DIFFRACTION|2.3|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2O|PCSK9-deltaC D374Y mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.62|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2P|PCSK9-deltaC D374A mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.62|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2Q|PCSK9-deltaC D374H mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.33|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2XTJ|The crystal structure of PCSK9 in complex with 1D05 Fab|X-RAY DIFFRACTION|2.7|HOMO SAPIENS|0|HYDROLASE/ANTIBODY","3BPS|PCSK9:EGF-A complex|X-RAY DIFFRACTION|2.41|Homo sapiens|0|HYDROLASE/Lipid Transport","3GCW|PCSK9:EGFA(H306Y)|X-RAY DIFFRACTION|2.7|Homo sapiens|0|PROTEIN BINDING","3GCX|PCSK9:EGFA (pH 7.4)|X-RAY DIFFRACTION|2.7|Homo sapiens|0|PROTEIN BINDING","3H42|Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody|X-RAY DIFFRACTION|2.3|Homo sapiens|0|HYDROLASE/IMMUNE SYSTEM","3M0C|The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor|X-RAY DIFFRACTION|7.01|Homo sapiens|0|PROTEIN BINDING","3P5B|The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation|X-RAY DIFFRACTION|3.3|Homo sapiens|0|HYDROLASE/LIPID BINDING PROTEIN","3P5C|The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation|X-RAY DIFFRACTION|4.2|Homo sapiens|0|HYDROLASE/LIPID BINDING PROTEIN","3SQO|PCSK9 J16 Fab complex|X-RAY DIFFRACTION|2.7|Homo sapiens|0|HYDROLASE/Immune system","4K8R|An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo|X-RAY DIFFRACTION|3.22|Homo sapiens|0|IMMUNE SYSTEM","4NE9|PCSK9 in complex with LDLR peptide|X-RAY DIFFRACTION|2.6|Homo sapiens|0|HYDROLASE","4NMX|PCSK9(deltaCRD) in complex with phage-derived inhibitory peptide 2-8|X-RAY DIFFRACTION|1.85|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/HYDROLASE INHIBITOR","4OV6|Crystal structure of PCSK9(53-451) with Adnectin|X-RAY DIFFRACTION|2.69|Homo sapiens|0|HYDROLASE/PROTEIN BINDING","5OCA|PCSK9:Fab Complex with Dextran Sulfate|X-RAY DIFFRACTION|2.3|Homo sapiens|0|HYDROLASE","5VL7|PCSK9 complex with Fab33|X-RAY DIFFRACTION|3.5|Homo sapiens|0|HYDROLASE","5VLA|Short PCSK9 delta-P' complex with Fusion2 peptide|X-RAY DIFFRACTION|2.4|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","5VLH|Short PCSK9 delta-P' complex with peptide Pep1|X-RAY DIFFRACTION|2.86|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","5VLK|Short PCSK9 delta-P' complex with shrunken peptide bearing homo-Arginine|X-RAY DIFFRACTION|2.2|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","5VLL|Short PCSK9 delta-P' complex with peptide Pep3|X-RAY DIFFRACTION|2.37|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE","5VLP|PCSK9 complex with LDLR antagonist peptide and Fab7G7|X-RAY DIFFRACTION|2.9|Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT|0|HYDROLASE","6E4Y|Anti-PCSK9 fab 6E2 bound to the N-terminal peptide from PCSK9, unmodified|X-RAY DIFFRACTION|2.24|Mus musculus; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6E4Z|Anti-PCSK9 fab 6E2 bound to the modified N-terminal peptide from PCSK9|X-RAY DIFFRACTION|2.202|Mus musculus; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6MV5|Anti-PCSK9 fab 6E2 bound to the N-terminal peptide from PCSK9 (E32K)|X-RAY DIFFRACTION|2.1|Mus musculus; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6OLZ|Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA|ELECTRON MICROSCOPY|3.9|Homo sapiens|0|RIBOSOME","6OM0|Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs|ELECTRON MICROSCOPY|3.1|Homo sapiens|0|RIBOSOME","6OM7|Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs|ELECTRON MICROSCOPY|3.7|Homo sapiens|0|RIBOSOME","6U26|PCSK9 in complex with compound 16|X-RAY DIFFRACTION|1.53|Homo sapiens|0|HYDROLASE/HYDROLASE Inhibitor","6U2F|PCSK9-Fab 7G7 complex bound to cis-1-amino-4-phenylcyclohexaneacyl-WNLK(hR)IGLLR - NH2|X-RAY DIFFRACTION|2.94|Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT|0|HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM","6U2N|PCSK9 in complex with compound 4|X-RAY DIFFRACTION|2.15|Homo sapiens|0|HYDROLASE","6U2P|PCSK9 in complex with compound 5|X-RAY DIFFRACTION|2.04|Homo sapiens|0|HYDROLASE","6U36|PCSK9 in complex with a Fab and compound 14|X-RAY DIFFRACTION|2.7|Homo sapiens|0|HYDROLASE/Immune System","6U38|PCSK9 in complex with a Fab and compound 8|X-RAY DIFFRACTION|2.73|Homo sapiens|0|HYDROLASE/Immune System","6U3I|Design of organo-peptides as bipartite PCSK9 antagonists|X-RAY DIFFRACTION|2.9|Homo sapiens; Mus musculus; SYNTHETIC CONSTRUCT|0|HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM","6U3X|PCSK9 in complex with compound 2|X-RAY DIFFRACTION|2.64|Homo sapiens|0|HYDROLASE","6XIB|PCSK9(deltaCRD) in complex with cyclic peptide 30|X-RAY DIFFRACTION|1.546|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","6XIC|PCSK9(deltaCRD) in complex with cyclic peptide 40|X-RAY DIFFRACTION|1.377|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","6XID|PCSK9(deltaCRD) in complex with cyclic peptide 51|X-RAY DIFFRACTION|1.482|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","6XIE|PCSK9(deltaCRD) in complex with cyclic peptide 77|X-RAY DIFFRACTION|1.43|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","6XIF|PCSK9(deltaCRD) in complex with cyclic peptide 83|X-RAY DIFFRACTION|1.774|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","7ANQ|Complete PCSK9 C-ter domain in complex with VHH P1.40|X-RAY DIFFRACTION|2.2|Homo sapiens; Lama glama|0|HYDROLASE","7KEV|PCSK9 in complex with a cyclic peptide LDLR disruptor|X-RAY DIFFRACTION|2.8|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIPID TRANSPORT, HYDROLASE","7KFA|PCSK9 in complex with PCSK9i a 13mer cyclic peptide LDLR disruptor|X-RAY DIFFRACTION|2.45|Homo sapiens; SYNTHETIC CONSTRUCT|0|LIPID TRANSPORT, HYDROLASE","7S5G|PCSK9 in complex with compound 19|X-RAY DIFFRACTION|2.041|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING,HYDROLASE","7S5H|PCSK9(deltaCRD) in complex with cyclic peptide 35|X-RAY DIFFRACTION|1.272|Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING,HYDROLASE","8FPO|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.997|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FPQ|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.503|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVL|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|1.961|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVM|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.852|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVN|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.71|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVO|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.652|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVP|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.602|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8FVQ|PCSK9 in complex with an inhibitor|X-RAY DIFFRACTION|2.57|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8VDV|pcsk9 in complex with inhibitor|X-RAY DIFFRACTION|1.972|Homo sapiens; SYNTHETIC CONSTRUCT|0|HYDROLASE/INHIBITOR","8WFR|The Crystal Structure of PCSK9 from Biortus.|X-RAY DIFFRACTION|1.95|Homo sapiens|0|HYDROLASE"]},{"input":"P01130","source":"P01130|Low-density lipoprotein receptor","targets":["1AJJ|LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING|X-RAY DIFFRACTION|1.7|Homo sapiens|0|RECEPTOR","1D2J|LDL RECEPTOR LIGAND-BINDING MODULE 6|SOLUTION NMR||Homo sapiens|0|SIGNALING PROTEIN","1F5Y|NMR STRUCTURE OF A CONCATEMER OF THE FIRST AND SECOND LIGAND-BINDING MODULES OF THE HUMAN LDL RECEPTOR|SOLUTION NMR||Homo sapiens|0|LIPID BINDING PROTEIN","1F8Z|NMR STRUCTURE OF THE SIXTH LIGAND-BINDING MODULE OF THE LDL RECEPTOR|SOLUTION NMR|||0|LIPID BINDING PROTEIN","1HJ7|NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures|SOLUTION NMR||HOMO SAPIENS|0|CELL-SURFACE RECEPTOR","1HZ8|SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR|SOLUTION NMR||Homo sapiens|0|LIPID BINDING PROTEIN","1I0U|SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR|SOLUTION NMR||Homo sapiens|0|LIPID BINDING PROTEIN","1IJQ|Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair|X-RAY DIFFRACTION|1.5|Homo sapiens|0|LIPID TRANSPORT","1LDL|THREE-DIMENSIONAL STRUCTURE OF A CYSTEINE-RICH REPEAT FROM THE LOW-DENSITY LIPOPROTEIN RECEPTOR|SOLUTION NMR||Homo sapiens|0|BINDING PROTEIN","1LDR|SECOND REPEAT OF THE LDL RECEPTOR LIGAND-BINDING DOMAIN|SOLUTION NMR||Homo sapiens|0|BINDING PROTEIN","1N7D|Extracellular domain of the LDL receptor|X-RAY DIFFRACTION|3.7|Homo sapiens|0|LIPID TRANSPORT","1XFE|Solution structure of the LA7-EGFA pair from the LDL receptor|SOLUTION NMR||Homo sapiens|0|LIPID TRANSPORT, ENDOCYTOSIS/EXOCYTOSIS","2FCW|Structure of a Complex Between the Pair of the LDL Receptor Ligand-Binding Modules 3-4 and the Receptor Associated Protein (RAP).|X-RAY DIFFRACTION|1.26|Homo sapiens|0|LIPID TRANSPORT/ENDOCYTOSIS/CHAPERONE","2KRI|Structure of a complex between domain V of beta2-glycoprotein I and the fourth ligand-binding module from LDLR determined with Haddock|SOLUTION NMR||Homo sapiens|0|PROTEIN BINDING/ENDOCYTOSIS","2LGP|Solution structure of LA45 from LDLR|SOLUTION NMR||Homo sapiens|0|PROTEIN BINDING","2M7P|RXFP1 utilises hydrophobic moieties on a signalling surface of the LDLa module to mediate receptor activation|SOLUTION NMR||Homo sapiens|0|PROTEIN BINDING","2MG9|Truncated EGF-A|SOLUTION NMR|||0|METAL BINDING PROTEIN","2W2M|WT PCSK9-DELTAC BOUND TO WT EGF-A OF LDLR|X-RAY DIFFRACTION|2.4|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2N|WT PCSK9-deltaC bound to EGF-A H306Y mutant of LDLR|X-RAY DIFFRACTION|2.3|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2O|PCSK9-deltaC D374Y mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.62|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2P|PCSK9-deltaC D374A mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.62|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","2W2Q|PCSK9-deltaC D374H mutant bound to WT EGF-A of LDLR|X-RAY DIFFRACTION|2.33|HOMO SAPIENS|0|HYDROLASE/RECEPTOR","3BPS|PCSK9:EGF-A complex|X-RAY DIFFRACTION|2.41|Homo sapiens|0|HYDROLASE/Lipid Transport","3GCW|PCSK9:EGFA(H306Y)|X-RAY DIFFRACTION|2.7|Homo sapiens|0|PROTEIN BINDING","3GCX|PCSK9:EGFA (pH 7.4)|X-RAY DIFFRACTION|2.7|Homo sapiens|0|PROTEIN BINDING","3M0C|The X-ray Crystal Structure of PCSK9 in Complex with the LDL receptor|X-RAY DIFFRACTION|7.01|Homo sapiens|0|PROTEIN BINDING","3P5B|The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation|X-RAY DIFFRACTION|3.3|Homo sapiens|0|HYDROLASE/LIPID BINDING PROTEIN","3P5C|The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation|X-RAY DIFFRACTION|4.2|Homo sapiens|0|HYDROLASE/LIPID BINDING PROTEIN","3SO6|Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain|X-RAY DIFFRACTION|1.37|Rattus norvegicus; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING/PROTEIN TRANSPORT","4NE9|PCSK9 in complex with LDLR peptide|X-RAY DIFFRACTION|2.6|Homo sapiens|0|HYDROLASE","5OY9|VSV G CR3|X-RAY DIFFRACTION|3.6|Homo sapiens; Vesicular stomatitis Indiana virus (strain Mudd-Summers)|0|VIRAL PROTEIN","5OYL|VSV G CR2|X-RAY DIFFRACTION|2.25|Homo sapiens; Recombinant vesicular stomatitis Indiana virus rVSV-G/GFP|0|VIRAL PROTEIN","9BD8|ApoB 100 beta barrel bound to LDLR beta propeller|ELECTRON MICROSCOPY|4.8|Homo sapiens|0|LIPID TRANSPORT","9BDE|Middle Region of Apolipoprotein B 100 bound to Low Density Lipoprotein Receptor|ELECTRON MICROSCOPY|4.18|Camelus bactrianus; Escherichia coli; Homo sapiens; Mus musculus; Staphylococcus aureus; Streptococcus sp. 'group G'|0|LIPID TRANSPORT","9BDT|Apolipoprotein B 100 bound to LDL receptor and legobody|ELECTRON MICROSCOPY|5.4|Camelus bactrianus; Escherichia coli; Homo sapiens; Mus musculus; Staphylococcus aureus|0|LIPID TRANSPORT","9COO|Nanobody 4 bound to Apolipoprotein B 100|ELECTRON MICROSCOPY|3.73|Camelus bactrianus; Escherichia coli; Homo sapiens; Mus musculus|0|LIPID TRANSPORT"]},{"input":"P08519","source":"P08519|Apolipoprotein(a)","targets":["1I71|HIGH RESOLUTION CRYSTAL STRUCTURE OF APOLIPOPROTEIN(A) KRINGLE IV TYPE 7: INSIGHTS INTO LIGAND BINDING|X-RAY DIFFRACTION|1.45|Homo sapiens|0|HYDROLASE","1JFN|SOLUTION STRUCTURE OF HUMAN APOLIPOPROTEIN(A) KRINGLE IV TYPE 6|SOLUTION NMR||Homo sapiens|0|LIPID TRANSPORT","1KIV|RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)|X-RAY DIFFRACTION|2.1|Homo sapiens|0|KRINGLE","2FEB|NMR Solution Structure, Dynamics and Binding Properties of the Kringle IV Type 8 module of apolipoprotein(a)|SOLUTION NMR||Homo sapiens|0|HYDROLASE","3KIV|RECOMBINANT KRINGLE IV-10/M66 VARIANT OF HUMAN APOLIPOPROTEIN(A)|X-RAY DIFFRACTION|1.8|Homo sapiens|0|KRINGLE","4BV5|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|2.1|HOMO SAPIENS|0|HYDROLASE","4BV7|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|HYDROLASE","4BVC|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|1.6|HOMO SAPIENS|0|HYDROLASE","4BVD|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|1.68|HOMO SAPIENS|0|HYDROLASE","4BVV|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|1.8|HOMO SAPIENS|0|HYDROLASE","4BVW|Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.|X-RAY DIFFRACTION|2|HOMO SAPIENS|0|HYDROLASE","4KIV|RECOMBINANT KRINGLE IV-10/W72R MUTANT OF HUMAN APOLIPOPROTEIN(A)|X-RAY DIFFRACTION|2.2|Homo sapiens|0|LYSINE BINDING SITE","6RX7|Structure of the KIV type 2 (KIV-2) domain of lipoprotein (a)|X-RAY DIFFRACTION|1.63|Homo sapiens|0|LIPID TRANSPORT","8TCE|Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3353871|X-RAY DIFFRACTION|1.07|Homo sapiens|0|LIPID BINDING PROTEIN","8V8Z|Lipoprotein(a) Kringle IV domain 8 - Lp(a) KIV8 in complex with LY3473329|X-RAY DIFFRACTION|2.01|Homo sapiens|0|LIPID BINDING PROTEIN","8V9B|Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732|X-RAY DIFFRACTION|1.19|Homo sapiens|0|LIPID BINDING PROTEIN"]},{"input":"P02649","source":"P02649|Apolipoprotein E","targets":["1B68|APOLIPOPROTEIN E4 (APOE4), 22K FRAGMENT|X-RAY DIFFRACTION|2|Homo sapiens|0|LIPID TRANSPORT","1BZ4|APOLIPOPROTEIN E3 (APO-E3), TRUNCATION MUTANT 165|X-RAY DIFFRACTION|1.85|Homo sapiens|0|LIPID BINDING PROTEIN","1EA8|Apolipoprotein E3 22kD fragment LYS146GLU mutant|X-RAY DIFFRACTION|1.95|HOMO SAPIENS|0|LIPID BINDING PROTEIN","1GS9|Apolipoprotein E4, 22k domain|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|LIPID BINDING PROTEIN","1H7I|Apolipoprotein E3 22kD fragment LYS146GLN mutant|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|LIPID BINDING PROTEIN","1LE2|STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E|X-RAY DIFFRACTION|3|Homo sapiens|0|LIPOPROTEIN","1LE4|STRUCTURAL BASIS FOR ALTERED FUNCTION IN THE COMMON MUTANTS OF HUMAN APOLIPOPROTEIN-E|X-RAY DIFFRACTION|2.5|Homo sapiens|0|LIPOPROTEIN","1LPE|THREE-DIMENSIONAL STRUCTURE OF THE LDL RECEPTOR-BINDING DOMAIN OF HUMAN APOLIPOPROTEIN E|X-RAY DIFFRACTION|2.25|Homo sapiens|0|LIPOPROTEIN","1NFN|APOLIPOPROTEIN E3 (APOE3)|X-RAY DIFFRACTION|1.8|Homo sapiens|0|LIPID TRANSPORT","1NFO|APOLIPOPROTEIN E2 (APOE2, D154A MUTATION)|X-RAY DIFFRACTION|2|Homo sapiens|0|LIPID TRANSPORT","1OEF|PEPTIDE OF HUMAN APOE RESIDUES 263-286, NMR, 5 STRUCTURES AT PH 4.8, 37 DEGREES CELSIUS AND PEPTIDE:SDS MOLE RATIO OF 1:90|SOLUTION NMR||Homo sapiens|0|APOLIPOPROTEIN","1OEG|PEPTIDE OF HUMAN APOE RESIDUES 267-289, NMR, 5 STRUCTURES AT PH 6.0, 37 DEGREES CELSIUS AND PEPTIDE:SDS MOLE RATIO OF 1:90|SOLUTION NMR||Homo sapiens|0|APOLIPOPROTEIN","1OR2|APOLIPOPROTEIN E3 (APOE3) TRUNCATION MUTANT 165|X-RAY DIFFRACTION|2.5|Homo sapiens|0|LIPID BINDING PROTEIN","1OR3|APOLIPOPROTEIN E3 (APOE3), TRIGONAL TRUNCATION MUTANT 165|X-RAY DIFFRACTION|1.73|Homo sapiens|0|LIPID BINDING PROTEIN","2KC3|NMR solution structure of complete receptor binding domain of human apolipoprotein E|SOLUTION NMR||Homo sapiens|0|LIPOPROTEIN","2KNY|Fusion construct of CR17 from LRP-1 and ApoE residues 130-149|SOLUTION NMR||Homo sapiens|0|METAL BINDING PROTEIN","2L7B|NMR Structure of full length apoE3|SOLUTION NMR||Homo sapiens|0|LIPID TRANSPORT","6IWB|Crystal structure of a computationally designed protein (LD3) in complex with BCL-2|X-RAY DIFFRACTION|2.5|Homo sapiens|0|APOPTOSIS","6NCN|Fragment-based Discovery of an apoE4 Stabilizer|X-RAY DIFFRACTION|1.82|Homo sapiens|0|LIPID TRANSPORT","6NCO|Fragment-based Discovery of an apoE4 Stabilizer|X-RAY DIFFRACTION|1.707|Homo sapiens|0|LIPID TRANSPORT","6V7M|Crystal structure of a proteolytically cleaved, amino terminal domain of apolipoprotein E3|X-RAY DIFFRACTION|2|Homo sapiens|0|LIPID TRANSPORT","7FCR|Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)|X-RAY DIFFRACTION|1.4|Homo sapiens|0|LIPID TRANSPORT","7FCS|Crystal structure of the N-terminal domain of mutants of Human Apolipoprotein-E (ApoE)|X-RAY DIFFRACTION|1.6|Homo sapiens|0|LIPID TRANSPORT","7UVJ|Rationally Designed ED1 Epitope-Scaffold Immunogen for SARS-CoV-2|X-RAY DIFFRACTION|1.99|Escherichia coli|0|DE NOVO PROTEIN","8AX8|Human Apolipoprotein E4 (ApoE4) N-terminal domain (space group P3121)|X-RAY DIFFRACTION|1.551|Homo sapiens|0|LIPID BINDING PROTEIN","8AX9|Human Apolipoprotein E4 (ApoE4) N-terminal domain (space group P212121)|X-RAY DIFFRACTION|1.549|Homo sapiens|0|LIPID BINDING PROTEIN","8CDY|N-terminal domain of human apolipoprotein E|X-RAY DIFFRACTION|1.9|Escherichia coli; Homo sapiens|0|LIPID TRANSPORT","8CE0|N-terminal domain of human apolipoprotein E|X-RAY DIFFRACTION|1.75|Escherichia coli; Homo sapiens|0|LIPID TRANSPORT","8GRX|APOE4 receptor in complex with APOE4 NTD|ELECTRON MICROSCOPY|3.0|Homo sapiens|0|IMMUNE SYSTEM"]},{"input":"P08887","source":"P08887|Interleukin-6 receptor subunit alpha","targets":["1N26|Crystal Structure of the extra-cellular domains of Human Interleukin-6 Receptor alpha chain|X-RAY DIFFRACTION|2.4|Homo sapiens|0|CYTOKINE","1P9M|Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex|X-RAY DIFFRACTION|3.65|Homo sapiens|0|signaling protein/cytokine","2ARW|The solution structure of the membrane proximal cytokine receptor domain of the human interleukin-6 receptor|SOLUTION NMR||Homo sapiens|0|CYTOKINE","5FUC|Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies|X-RAY DIFFRACTION|2.7|CAMELUS DROMEDARIUS; HOMO SAPIENS|0|IMMUNE SYSTEM","7DC8|Crystal structure of Switch Ab Fab and hIL6R in complex with ATP|X-RAY DIFFRACTION|2.757|Homo sapiens|0|IMMUNE SYSTEM","8D82|Cryo-EM structure of human IL-6 signaling complex in detergent: model containing full extracellular domains|ELECTRON MICROSCOPY|3.22|Homo sapiens|0|CYTOKINE","8IOW|Cryo-EM structure of the sarilumab Fab/IL-6R complex|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|IMMUNE SYSTEM","8J6F|Cryo-EM structure of the Tocilizumab Fab/IL-6R complex|ELECTRON MICROSCOPY|3.3|Homo sapiens|0|IMMUNE SYSTEM","8QY5|Structure of interleukin 6.|ELECTRON MICROSCOPY|3.1|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM","8QY6|Structure of interleukin 6 (gp130 P496L mutant).|ELECTRON MICROSCOPY|3.16|Homo sapiens; Mus musculus|0|IMMUNE SYSTEM"]},{"input":"P29474","source":"P29474|Nitric oxide synthase 3","targets":["1M9J|human endothelial nitric oxide synthase with chlorzoxazone bound|X-RAY DIFFRACTION|2.43|Homo sapiens|0|OXIDOREDUCTASE","1M9K|Human Endothelial Nitric Oxide Synthase with 7-Nitroindazole Bound|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE","1M9M|human endothelial nitric oxide synthase with 6-nitroindazole bound|X-RAY DIFFRACTION|1.96|Homo sapiens|0|OXIDOREDUCTASE","1M9Q|human endothelial nitric oxide synthase with 5-nitroindazole bound|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE","1M9R|human endothelial nitric oxide synthase with 3-Bromo-7-Nitroindazole bound|X-RAY DIFFRACTION|2.56|Homo sapiens|0|OXIDOREDUCTASE","1NIW|Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin|X-RAY DIFFRACTION|2.05|Rattus norvegicus; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/OXIDOREDUCTASE","2LL7|Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide|SOLUTION NMR||Homo sapiens|0|OXIDOREDUCTASE","2MG5|Solution Structure of Calmodulin bound to the target peptide of Endothelial Nitrogen Oxide Synthase phosphorylated at Thr495|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|Metal binding protein/target peptide","2N8J|Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide Synthase Calmodulin Binding Domain Peptide at Physiological Calcium Concentration|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|PROTEIN BINDING","3EAH|Structure of inhibited human eNOS oxygenase domain|X-RAY DIFFRACTION|2.44|Homo sapiens|0|OXIDOREDUCTASE","3NOS|HUMAN ENDOTHELIAL NITRIC OXIDE SYNTHASE WITH ARGININE SUBSTRATE|X-RAY DIFFRACTION|2.4|Homo sapiens|0|OXIDOREDUCTASE","4D1O|Structure of human endothelial nitric oxide synthase heme domain with L-Arg bound|X-RAY DIFFRACTION|1.819|HOMO SAPIENS|0|OXIDOREDUCTASE","4D1P|Structure of human endothelial nitric oxide synthase heme domain IN COMPLEX WITH 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2-YL)METHOXY) METHYL)PYRROLIDIN-3-YL)OXY) METHYL)-4-METHYLPYRIDIN-2-AMINE|X-RAY DIFFRACTION|1.731|HOMO SAPIENS|0|OXIDOREDUCTASE","5UO8|Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-aminoquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile|X-RAY DIFFRACTION|2.18|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5UO9|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine|X-RAY DIFFRACTION|2.19|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOA|Structure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOB|Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile|X-RAY DIFFRACTION|2.292|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5UOC|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","5VVB|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Aminoquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5VVC|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)-2-methylbenzonitrile|X-RAY DIFFRACTION|2.4|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5VVD|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(2-(((2-Amino-4-methylquinolin-7-yl)methyl)amino)ethyl)benzonitrile|X-RAY DIFFRACTION|2.25|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","5XOF|Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I|X-RAY DIFFRACTION|1.963|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6AV6|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-Fluoro-5-(3-(methylamino)propyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.08|Homo sapiens|0|OXIDOREDUCTASE","6AV7|Structure of human endothelial nitric oxide synthase heme domain in complex with HW69|X-RAY DIFFRACTION|1.916|Homo sapiens|0|OXIDOREDUCTASE","6CIE|Structure of human endothelial nitric oxide synthase heme domain in complex with N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquino-lin-6-yl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE","6CIF|Structure of the human endothelial nitric oxide synthase heme domain in complex with N-(1-(Piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","6NH1|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.216|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH2|Structure of human endothelial nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.29|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH3|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.01|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH4|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.27|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH5|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.959|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH6|Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.189|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH7|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NH8|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6NHF|Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.83|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE inhibitor","6POU|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(4-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.194|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POV|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.047|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POW|Structure of human endotheial nitric oxide synthase heme domain in complex with 7-(5-(Aminomethyl)pyridin-3-yl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POX|Structure of human endothelialnitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-ethoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.197|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POY|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-propoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.3|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6POZ|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-isopropoxyphenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP0|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(cyclobutylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.97|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP1|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(cyclopropylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.76|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP2|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-((4-(2-Amino-4-methylquinolin-7-yl)-2-(aminomethyl)phenoxy)methyl)benzonitrile|X-RAY DIFFRACTION|2.02|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP3|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-2-ylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","6PP4|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(3-(Aminomethyl)-4-(pyridin-3-ylmethoxy)phenyl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","7M56|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine|X-RAY DIFFRACTION|1.957|Homo sapiens|0|OXIDOREDUCTASE","7TSG|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(dimethylamino)propyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.85|Homo sapiens|0|OXIDOREDUCTASE","7TSH|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)propyl)pyridin-2-amine|X-RAY DIFFRACTION|2.145|Homo sapiens|0|OXIDOREDUCTASE","7TSI|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE","7TSK|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(methylamino)prop-1-yn-1-yl)pyridin-2-amine|X-RAY DIFFRACTION|2.049|Homo sapiens|0|OXIDOREDUCTASE","7TSL|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)propyl)pyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","7TSM|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(3-(4-methylpiperazin-1-yl)prop-1-yn-1-yl)pyridin-2-amine bishydrochloride|X-RAY DIFFRACTION|1.85|Homo sapiens|0|OXIDOREDUCTASE","7TSN|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.08|Homo sapiens|0|OXIDOREDUCTASE","7TSO|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3,3-difluoroazetidin-1-yl)propyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","7TSP|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(4,4-difluoropiperidin-1-yl)prop-1-yn-1-yl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","7UAO|Structure of human endothelial nitric oxide synthase heme domain in complex with (6-(3-(4,4-difluoropiperidin-1-yl)propyl)-4-methylpyridin-2-amine)|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","8FGN|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","8FGO|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.799|Homo sapiens|0|OXIDOREDUCTASE","8FGP|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methoxypyridin-2-amine|X-RAY DIFFRACTION|1.88|Homo sapiens|0|OXIDOREDUCTASE","8FGQ|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-6-methylpyrimidin-2-amine|X-RAY DIFFRACTION|2.2|Homo sapiens|0|OXIDOREDUCTASE","8FGR|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-aminoethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.98|Homo sapiens|0|OXIDOREDUCTASE","8FGS|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(diethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8449|Homo sapiens|0|OXIDOREDUCTASE","8FGT|Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(2,3-difluoro-5-(2-(4-methylpiperazin-1-yl)ethyl)phenethyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","8FGU|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(difluoromethyl)-6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","8UFR|Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.871|Homo sapiens|0|OXIDOREDUCTASE","8UFS|Structure of human endothelial nitric oxide synthase E361Q mutant heme domain obtain after soaking crystal with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","8UFT|Structure of human endothelial nitric oxide synthase P370N mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine|X-RAY DIFFRACTION|1.78|Homo sapiens|0|OXIDOREDUCTASE","8UFU|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(9-amino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)-4-methylquinolin-2-amine|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","9CW2|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-6-(3-((methylamino)methyl)phenyl)pyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW4|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(3-fluoro-5-((methylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW5|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-6-(3-((methylamino)methyl)-5-(trifluoromethyl)phenyl)pyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.88|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW6|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(3-chloro-5-((dimethylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.151|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW7|Structure of human endothelial nitric oxide synthase heme domain bound with 4-methyl-5'-((methylamino)methyl)-[2,3'-bipyridin]-6-amine dihydrochloride|X-RAY DIFFRACTION|1.83|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW8|Structure of human endothelial nitric oxide synthase heme domain bound with 3-(6-amino-4-methylpyridin-2-yl)-5-((methylamino)methyl)benzonitrile dihydrochloride|X-RAY DIFFRACTION|1.92|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CW9|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(2,3-difluoro-5-((methylamino)methyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|2.12|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWD|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((dimethylamino)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.92|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWI|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((3,3-difluoroazetidin-1-yl)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.73|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWJ|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(5-((4,4-difluoropiperidin-1-yl)methyl)-2,3-difluorophenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9CWK|Structure of human endothelial nitric oxide synthase heme domain bound with 6-(2,3-difluoro-5-(2-(methylamino)ethyl)phenyl)-4-methylpyridin-2-amine dihydrochloride|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/INHIBITOR","9C1Z|Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(((4-(6-aminopyridin-2-yl)butyl)amino)methyl)phenoxy)methyl)quinolin-2-amine|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","9MWN|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|2|Homo sapiens|0|OXIDOREDUCTASE","9MWO|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.76|Homo sapiens|0|OXIDOREDUCTASE","9MWP|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(furan-3-carboximidamido)benzyl)amino)ethyl)phenyl)furan-3-carboximidamide|X-RAY DIFFRACTION|1.86|Homo sapiens|0|OXIDOREDUCTASE","9MWQ|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(isoxazole-3-carboximidamido)benzyl)amino)ethyl)phenyl)isoxazole-3-carboximidamide|X-RAY DIFFRACTION|1.938|Homo sapiens|0|OXIDOREDUCTASE","9MWR|Structure of human endothelial nitric oxide synthase heme domain bound with N-(4-(2-((3-(thiazole-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-2-carboximidamide|X-RAY DIFFRACTION|1.97|Homo sapiens|0|OXIDOREDUCTASE","9MWS|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(2-((3-(thiazole-5-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.899|Homo sapiens|0|OXIDOREDUCTASE","9MWT|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(2-((3-(furan-2-carboximidamido)benzyl)amino)ethyl)phenyl)furan-2-carboximidamide|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE","9MWU|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)furan-2-carboximidamide|X-RAY DIFFRACTION|1.736|Homo sapiens|0|OXIDOREDUCTASE","9MWV|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiophene-2-carboximidamide|X-RAY DIFFRACTION|1.896|Homo sapiens|0|OXIDOREDUCTASE","9MWW|Structure of human endothelial nitric oxide synthase heme domain bound with N-(3-(((2-(3-(aminomethyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)methyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE","9MWX|Structure of human endothelial nitric oxide synthase heme domain bound withN-(4-(2-((3-(thiazole-5-carboximidamido)benzyl)amino)ethyl)phenyl)thiazole-5-carboximidamide|X-RAY DIFFRACTION|1.839|Homo sapiens|0|OXIDOREDUCTASE","9MZ1|Structure of human endothelial nitric oxide synthase heme domain bound with 7-(3-aminomethyl)phenyl-6-fluoro-4-methylquinoin-2-amine|X-RAY DIFFRACTION|2.05|Homo sapiens|0|OXIDOREDUCTASE","9MZ2|Structure of human endothelial nitric oxide synthase heme domain bound with 2-(2-amino-6-fluoro-4-methylquinolin-7-yl)-5-(aminomethyl)phenol|X-RAY DIFFRACTION|1.99|Homo sapiens|0|OXIDOREDUCTASE","9MZ3|Structure of human endothelial nitric oxide synthase heme domain bound 2-(2-amino-6-fluoro-4-methylquinolin-7-yl)-5-(2-aminoethyl)phenol|X-RAY DIFFRACTION|1.95|Homo sapiens|0|OXIDOREDUCTASE","9MZ4|Structure of human endothelial nitric oxide synthase heme domain bound 7-(3-(aminomethyl)-4-(cyclopropylmethoxy)phenyl)-6-fluoro-4-methylquinolin-2-amine|X-RAY DIFFRACTION|1.94|Homo sapiens|0|OXIDOREDUCTASE","9Q4X|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(dimethylamino)ethyl)-2,3-difluorophenoxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.15|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q4Y|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((2,3-difluoro-5-(2-(methylamino)ethyl)phenoxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|2.1|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q4Z|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(ethyl(methyl)amino)ethyl)-2,3-difluorophenxy)methyl)-4-methylphridin-2-amine|X-RAY DIFFRACTION|1.9|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR","9Q51|Structure of human endothelial nitric oxide synthase heme domain bound with 6-((5-(2-(diethylamino)ethyl)-2,3-difluorophenxy)methyl)-4-methylpyridin-2-amine|X-RAY DIFFRACTION|1.8|Homo sapiens|0|OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR"]}]}