{"context":{"query":">>uniprot>>pdb","source_dataset":"uniprot","target_dataset":"pdb"},"stats":{"queried":1,"total":79,"mapped":1},"pagination":{"has_next":false},"schema":"id|title|method|resolution|source_organism|chain_count|header","mappings":[{"input":"Q9UM73","source":"Q9UM73|ALK tyrosine kinase receptor","targets":["2KUP|Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN/ONCOPROTEIN","2KUQ|Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK|SOLUTION NMR||Homo sapiens; synthetic construct|0|SIGNALING PROTEIN","2XB7|Structure of Human Anaplastic Lymphoma Kinase in complex with NVP- TAE684|X-RAY DIFFRACTION|2.5|HOMO SAPIENS|0|TRANSFERASE","2XBA|Structure of Human Anaplastic Lymphoma Kinase in complex with PHA- E429|X-RAY DIFFRACTION|1.95|HOMO SAPIENS|0|TRANSFERASE","2XP2|Structure of the Human Anaplastic Lymphoma Kinase in Complex with Crizotinib (PF-02341066)|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","2YFX|Structure of L1196M Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|TRANSFERASE","2YHV|Structure of L1196M Mutant Anaplastic Lymphoma Kinase|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","2YJR|Structure of F1174L Mutant Anaplastic Lymphoma Kinase|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","2YJS|Structure of C1156Y Mutant Anaplastic Lymphoma Kinase|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","2YS5|Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK|SOLUTION NMR||Homo sapiens; SYNTHETIC CONSTRUCT|0|SIGNALING PROTEIN","2YT2|Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK|SOLUTION NMR||Homo sapiens|0|SIGNALING PROTEIN","3AOX|X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802|X-RAY DIFFRACTION|1.75|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","3L9P|Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain|X-RAY DIFFRACTION|1.8|Homo sapiens|0|TRANSFERASE","3LCS|Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain|X-RAY DIFFRACTION|1.95|Homo sapiens|0|TRANSFERASE","3LCT|Crystal Structure of the Anaplastic Lymphoma Kinase Catalytic Domain|X-RAY DIFFRACTION|2.1|Homo sapiens|0|TRANSFERASE","4ANL|Structure of G1269A Mutant Anaplastic Lymphoma Kinase|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|TRANSFERASE","4ANQ|Structure of G1269A Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|1.76|HOMO SAPIENS|0|TRANSFERASE","4ANS|Structure of L1196M,G1269A Double Mutant Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|1.85|HOMO SAPIENS|0|TRANSFERASE","4CCB|Structure of the Human Anaplastic Lymphoma Kinase in Complex with 3-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy)-5-(5-methyl-1H- pyrazol-4-yl)pyridin-2-amine|X-RAY DIFFRACTION|2.03|HOMO SAPIENS|0|TRANSFERASE","4CCU|Structure of the Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy) pyridin-3-yl)-4-methylthiazol-2-yl)propan-2-ol|X-RAY DIFFRACTION|2|HOMO SAPIENS|0|TRANSFERASE","4CD0|Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2- yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol|X-RAY DIFFRACTION|2.23|HOMO SAPIENS|0|TRANSFERASE","4CLI|Structure of the Human Anaplastic Lymphoma Kinase in Complex with PF- 06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16, 17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).|X-RAY DIFFRACTION|2.05|HOMO SAPIENS|0|TRANSFERASE","4CLJ|Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).|X-RAY DIFFRACTION|1.66|HOMO SAPIENS|0|TRANSFERASE","4CMO|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 2-((1R)-1-((3-amino-6-(2-methoxypyridin-3-yl)pyrazin-2-yl) oxy)ethyl)-4-fluoro-N-methylbenzamide|X-RAY DIFFRACTION|2.05|HOMO SAPIENS|0|TRANSFERASE","4CMT|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 3-((1R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)ethoxy)- 5-(3-(methylsulfonyl)phenyl)pyridin-2-amine|X-RAY DIFFRACTION|1.73|HOMO SAPIENS|0|TRANSFERASE","4CMU|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (10R)-7-amino-12-fluoro-1,3,10,16-tetramethyl-16,17-dihydro- 1H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecin-15(10H)-one|X-RAY DIFFRACTION|1.8|HOMO SAPIENS|0|TRANSFERASE","4CNH|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 3-((1R)-1-(5-fluoro-2-methoxyphenyl)ethoxy)-5-(1-methyl-1H- 1,2,3-triazol-5-yl)pyridin-2-amine|X-RAY DIFFRACTION|1.9|HOMO SAPIENS|0|TRANSFERASE","4CTB|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile|X-RAY DIFFRACTION|1.79|HOMO SAPIENS|0|TRANSFERASE","4CTC|Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor 7-amino-3-cyclopropyl-12-fluoro-1,10,16-trimethyl-16,17- dihydro-1H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecin-15(10H)-one|X-RAY DIFFRACTION|2.03|HOMO SAPIENS|0|TRANSFERASE","4DCE|Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor|X-RAY DIFFRACTION|2.03|Homo sapiens|0|Transferase/Inhibitor","4FNW|Crystal structure of the apo F1174L anaplastic lymphoma kinase catalytic domain|X-RAY DIFFRACTION|1.75|Homo sapiens|0|TRANSFERASE","4FNX|Crystal structure of the apo R1275Q anaplastic lymphoma kinase catalytic domain|X-RAY DIFFRACTION|1.7|Homo sapiens|0|TRANSFERASE","4FNY|Crystal structure of the R1275Q anaplastic lymphoma kinase catalytic domain in complex with a benzoxazole inhibitor|X-RAY DIFFRACTION|2.45|Homo sapiens|0|Transferase/Inhibitor","4FNZ|Crystal structure of human anaplastic lymphoma kinase in complex with piperidine-carboxamide inhibitor 2|X-RAY DIFFRACTION|2.6|Homo sapiens|0|Transferase/Inhibitor","4FOB|Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1|X-RAY DIFFRACTION|1.9|Homo sapiens|0|Transferase/Inhibitor","4FOC|Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 2|X-RAY DIFFRACTION|1.7|Homo sapiens|0|Transferase/Inhibitor","4FOD|Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36|X-RAY DIFFRACTION|2|Homo sapiens|0|Transferase/Inhibitor","4JOA|Crystal Structure of Human Anaplastic Lymphoma Kinase in complex with 7-azaindole based inhibitor|X-RAY DIFFRACTION|2.7|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4MKC|Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378|X-RAY DIFFRACTION|2.01|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","4TT7|Crystal structure of human ALK with a covalent modification|X-RAY DIFFRACTION|2.1|Homo sapiens|0|TRANSFERASE","4Z55|Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378|X-RAY DIFFRACTION|1.55|Homo sapiens|0|Transferase/Transferase Inhibitor","5A9U|Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).|X-RAY DIFFRACTION|1.6|HOMO SAPIENS|0|TRANSFERASE","5AA8|Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).|X-RAY DIFFRACTION|1.86|HOMO SAPIENS|0|TRANSFERASE","5AA9|Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).|X-RAY DIFFRACTION|1.93|HOMO SAPIENS|0|TRANSFERASE","5AAA|Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|1.73|HOMO SAPIENS|0|TRANSFERASE","5AAB|Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|2.2|HOMO SAPIENS|0|TRANSFERASE","5AAC|Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|TRANSFERASE","5FTO|Crystal structure of the ALK kinase domain in complex with Entrectinib|X-RAY DIFFRACTION|2.22|HOMO SAPIENS|0|TRANSFERASE","5FTQ|Crystal structure of the ALK kinase domain in complex with Cmpd 17|X-RAY DIFFRACTION|1.7|HOMO SAPIENS|0|TRANSFERASE","5IMX|Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine|X-RAY DIFFRACTION|2.12|Homo sapiens|0|TRANSFERASE/TRANSFERASE INHIBITOR","5IUG|Crystal Structure of Anaplastic Lymphoma Kinase (ALK) in complex with 5a|X-RAY DIFFRACTION|1.93|Homo sapiens|0|TRANSFERASE","5IUH|Crystal Structure of the Anaplastic Lymphoma Kinase (ALK) in complex with 5d|X-RAY DIFFRACTION|2.1|Homo sapiens|0|TRANSFERASE","5IUI|Crystal Structure of Anaplastic Lyphoma Kinase (ALK) in complex with 4|X-RAY DIFFRACTION|1.88|Homo sapiens|0|TRANSFERASE","5KZ0|Structure of Human Anaplastic Lymphoma Kinase in Complex With 2-[(1R)-1-{[2-amino-5-(1,3-dimethyl-1H-pyrazol-4-yl)pyridin-3-yl]oxy}ethyl]-4-fluoro-N,N-dimethylbenzamide|X-RAY DIFFRACTION|2.3|Homo sapiens|0|Transferase/Transferase Inhibitor","5VZ5|Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501|X-RAY DIFFRACTION|2.5901|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6AT9|Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-A*0101|X-RAY DIFFRACTION|2.9503|Homo sapiens; SYNTHETIC CONSTRUCT|0|IMMUNE SYSTEM","6CDT|Structure of Human Anaplastic Lymphoma Kinase Domain|X-RAY DIFFRACTION|1.8|Homo sapiens|0|TRANSFERASE","6E0R|hALK in complex with compound 7 N-((1S)-1-(5-fluoropyridin-2-yl)ethyl)-1-(5-methyl-1H-pyrazol-3-yl)-3-(oxetan-3-ylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-6-amine|X-RAY DIFFRACTION|2.303|Homo sapiens|0|PROTEIN BINDING","6EBW|hALK in complex with compound 9 (6-(((1S)-1-(5-Fluoropyridin-2-yl)ethyl)amino)-1-(3-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)(morpholin-4-yl)methanone|X-RAY DIFFRACTION|2.455|Homo sapiens|0|TRANSFERASE/INHIBITOR","6EDL|hALK in complex with compound 1 (S)-N-(1-(2,4-difluorophenyl)ethyl)-3-(3-methyl-1H-pyrazol-5-yl)imidazo[1,2-b]pyridazin-6-amine|X-RAY DIFFRACTION|2.799|Homo sapiens|0|TRANSFERASE/INHIBITOR","6MX8|Crystal structure of anaplastic lymphoma kinase (ALK) bound by Brigatinib|X-RAY DIFFRACTION|1.96|Homo sapiens|0|TRANSFERASE","7BTT|A X-ray cocrystal structure of XMU-MP-5 bound to the ALK kinase domain|X-RAY DIFFRACTION|1.86|Homo sapiens|0|TRANSFERASE","7JY4|hALK in complex with ((1S,2S)-1-(2,4-difluorophenyl)-2-(2-(3-methyl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenoxy)cyclopropyl)methanamine|X-RAY DIFFRACTION|2.42|Homo sapiens|0|TRANSFERASE","7JYR|hALK in complex with 1-[(1R,2R)-1-(2,4-difluorophenyl)-2-[2-(5-methyl-1H-pyrazol-3-yl)-4-(trifluoromethyl)phenoxy]cyclopropyl]methanamine|X-RAY DIFFRACTION|2.32|Homo sapiens|0|TRANSFERASE","7JYS|hALK in complex with 3-(3-chlorophenyl)-5-methyl-1H-pyrazole|X-RAY DIFFRACTION|2.22|Homo sapiens|0|TRANSFERASE","7JYT|hALK in complex with 3-(3-methyl-1H-pyrazol-5-yl)pyridine|X-RAY DIFFRACTION|2|Homo sapiens|0|TRANSFERASE","7LRZ|Structure of the Human ALK GRD|X-RAY DIFFRACTION|1.91|Homo sapiens|0|TRANSFERASE","7LS0|Structure of the Human ALK GRD bound to AUG|X-RAY DIFFRACTION|3.05|Homo sapiens|0|TRANSFERASE/TRANSFERASE ACTIVATOR","7MZW|Anaplastic lymphoma kinase (ALK) extracellular ligand binding region 673-1025|SOLUTION NMR||Homo sapiens|0|TRANSFERASE","7MZY|Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986|X-RAY DIFFRACTION|1.5|Homo sapiens|0|TRANSFERASE","7N00|Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha|ELECTRON MICROSCOPY|2.27|Homo sapiens|0|TRANSFERASE","7NWZ|ALK:ALKAL2 complex|X-RAY DIFFRACTION|4.17|Homo sapiens|0|PROTEIN BINDING","7NX3|Crystal structure of ALK in complex with Fab324|X-RAY DIFFRACTION|2.81|Homo sapiens; Mus musculus|0|PROTEIN BINDING","7NX4|Crystal structure of the TG and EGF-like domains of ALK|X-RAY DIFFRACTION|3|Homo sapiens|0|PROTEIN BINDING","7R7K|Structure of Human Anaplastic Lymphoma Kinase Domain in complex with (4-[6-amino-5-[(1~{R})-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-3-pyridyl]isoindolin-1-one)|X-RAY DIFFRACTION|1.831|Homo sapiens|0|TRANSFERASE","7R7R|Structure of Human Anaplastic Lymphoma Kinase Domain in complex with ((2~{R})-2-[5-[6-amino-5-[(1~{R})-1-[5-fluoro-2-(triazol-2-yl)phenyl]ethoxy]-3-pyridyl]-4-methyl-thiazol-2-yl]propane-1,2-diol)|X-RAY DIFFRACTION|1.935|Homo sapiens|0|TRANSFERASE","8ARJ|Anaplastic Lymphoma Kinase with a novel carboline inhibitor|X-RAY DIFFRACTION|1.645|Homo sapiens|0|ANTITUMOR PROTEIN","9G5I|Cryo-EM structure of a 2:1 ALK:ALKAL2 complex obtained after re-processing of EMPIAR-10930 data|ELECTRON MICROSCOPY|3.2|Homo sapiens|0|CYTOKINE","9GBE|Structure of Human Anaplastic Lymphoma Kinase (ALK) harboring the G1202R/L1196M Compound Mutation in Complex with NVL-655|X-RAY DIFFRACTION|1.58|Homo sapiens|0|ONCOPROTEIN"]}]}