{"context":{"query":">>hgnc>>ensembl>>uniprot>>reactome","source_dataset":"hgnc","target_dataset":"reactome"},"stats":{"queried":5,"total":26,"mapped":3},"pagination":{"has_next":false},"schema":"id|name|tax_id|is_disease_pathway","mappings":[{"input":"SOD1","source":"HGNC:11179|superoxide dismutase 1","targets":["R-HSA-114608|Platelet degranulation |9606|false","R-HSA-3299685|Detoxification of Reactive Oxygen Species|9606|false","R-HSA-8950505|Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation|9606|false"]},{"input":"FUS","source":"HGNC:4010|FUS RNA binding protein","targets":["R-HSA-72163|mRNA Splicing - Major Pathway|9606|false","R-HSA-72203|Processing of Capped Intron-Containing Pre-mRNA|9606|false","R-HSA-9770562|mRNA Polyadenylation|9606|false","R-HSA-9918481|Dengue Virus-Host Interactions|9606|true"]},{"input":"TBK1","source":"HGNC:11584|TANK binding kinase 1","targets":["R-HSA-1606341|IRF3 mediated activation of type 1 IFN|9606|false","R-HSA-168928|DDX58/IFIH1-mediated induction of interferon-alpha/beta|9606|false","R-HSA-3134975|Regulation of innate immune responses to cytosolic DNA|9606|false","R-HSA-3249367|STAT6-mediated induction of chemokines|9606|false","R-HSA-3270619|IRF3-mediated induction of type I IFN|9606|false","R-HSA-5205685|PINK1-PRKN Mediated Mitophagy|9606|false","R-HSA-5357786|TNFR1-induced proapoptotic signaling|9606|false","R-HSA-5357905|Regulation of TNFR1 signaling|9606|false","R-HSA-9008059|Interleukin-37 signaling|9606|false","R-HSA-9013973|TICAM1-dependent activation of IRF3/IRF7|9606|false","R-HSA-918233|TRAF3-dependent IRF activation pathway|9606|false","R-HSA-933541|TRAF6 mediated IRF7 activation|9606|false","R-HSA-936440|Negative regulators of DDX58/IFIH1 signaling|9606|false","R-HSA-936964|Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)|9606|false","R-HSA-9679191|Potential therapeutics for SARS|9606|true","R-HSA-9692916|SARS-CoV-1 activates/modulates innate immune responses|9606|true","R-HSA-9705671|SARS-CoV-2 activates/modulates innate and adaptive immune responses|9606|true","R-HSA-9824878|Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 |9606|false","R-HSA-9828211|Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation|9606|false"]}],"not_found":["TARDBP","C9orf72"]}