Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417198 | 0.87 | NOTUM (0.53) | NOTUMCYP11B1CYP11B2CDC7KDM4E | |
| SCHEMBL2474356 | 0.85 | FFAR4 (0.44) | CDC7FFAR4KDM4EALDH1A1HPGD | |
| SCHEMBL30622606 | 0.85 | FFAR4 (0.44) | CDC7FFAR4KDM4EALDH1A1HPGD | |
| SCHEMBL13656872 | 0.82 | FFAR4 (0.41) | NOTUMCYP11B1CYP11B2CDC7FFAR4 | |
| SCHEMBL1876083 | 0.80 | PIK3CD (0.44) | CDC7FFAR4HTR6 | |
| SCHEMBL23360853 | 0.79 | NOTUM (0.47) | NOTUMCYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL1248298 | 0.79 | TSHR (0.60) | FFAR4KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL793815 | 0.79 | NOTUM (0.47) | NOTUMCYP11B1CYP11B2KDM4EALDH1A1 | |
| SCHEMBL16824129 | 0.78 | OXER1 (0.48) | CYP11B1CYP11B2CDC7FFAR4KDM4E | |
| SCHEMBL28980345 | 0.77 | DYRK1A (0.40) | CDC7FFAR4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752256-B | Preparation method of N-acyl indole compound based on carboxylic acid alkenyl ester as acylation reagent | 六盘水师范学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-108752256-A | A kind of N- acyl indol class compounds process for production thereof based on alkenyl carboxylate as acylting agent | 六盘水师范学院 | 2018-11-06 | — | — | CN | disclosed |
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | PROGENICS PHARMACEUTICALS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009151-A1 | Triazines And Related Compounds Having Antiviral Activity, Compositions And Methods Thereof | HAVCR2, ZC3HAV1, MAVS | NOTUM 1938/4885CYP11B1 1255/4885CYP11B2 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.