Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365971 | 0.85 | MAPK14 (0.50) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10366595 | 0.85 | LMNA (0.46) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10368553 | 0.82 | HPGD (0.52) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10365977 | 0.81 | RIPK2 (0.63) | POLBALDH1A1HPGDRAB9AMAPK1 | |
| SCHEMBL6963674 | 0.81 | POLB (0.55) | POLBALDH1A1HPGDMAPK1RIPK2 | |
| SCHEMBL10365404 | 0.80 | POLB (0.51) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10366102 | 0.80 | HPGD (0.50) | POLBALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL10366707 | 0.79 | POLB (0.52) | POLBNPC1RAB9A | |
| SCHEMBL10368592 | 0.79 | MAPK1 (0.44) | ALDH1A1HPGDNPC1RAB9AMAPK1 | |
| SCHEMBL10340537 | 0.78 | ALDH1A1 (0.68) | ALDH1A1HPGDRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |
| US-4589905-A | TERRESTRIAL AND AQUATIC APPLICATIONS | ELI LILLY AND COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0151867-A2 | Cyanopyrazole herbicides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |