Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.62 |
| ▸ | HTR3A | P46098 | 3/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.58 |
| ▸ | HTR3B | O95264 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082656 | 0.85 | HTR1A (0.59) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL15881097 | 0.84 | SETDB1 (0.52) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL15880500 | 0.82 | POLB (0.49) | HTR1ASLC6A2SLC6A4SLC6A3ADRB1 | |
| SCHEMBL15881007 | 0.82 | DRD2 (0.59) | HTR1ADRD2DRD3 | |
| SCHEMBL7524534 | 0.80 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL255189 | 0.80 | HTR1A (0.68) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL787250 | 0.78 | MAPT (0.69) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL16528267 | 0.78 | MAPT (0.69) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Bromide SCHEMBL10621563 | 0.78 | HTR1A (0.66) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL8634780 | 0.77 | SMN1; SMN2 (0.48) | DRD2DRD3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547505-A | ANTIULCER, ANTIPHLOGISTIC, AND ANTISECRETORY AGENT | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-10-15 | — | — | US | disclosed |