SCHEMBL16613301

SCHEMBL16613301

c1ccc(-c2nc(-n3c4ccccc4c4ccccc43)nc3cocc23)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.41
KDM4E B2RXH2 5/20 0.37
NPC1 O15118 2/20 0.37
METAP1 P53582 4/20 0.36
LRRK2 Q5S007 1/20 0.35
NPY5R Q15761 1/20 0.35
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.33
CCR1 P32246 2/20 0.33
CCR5 P51681 2/20 0.33
CCR8 P51685 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
BLM P54132 1/20 0.33
HIF1A Q16665 1/20 0.33
DOHH Q9BU89 1/20 0.33
P4HTM Q9NXG6 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613351 0.89 AHR (0.37) MCL1KDM4ENPC1METAP1LRRK2
SCHEMBL12014847 0.86 MCL1 (0.47) MCL1KDM4ENPC1METAP1LMNA
SCHEMBL16613396 0.81 KDM4E (0.48) KDM4ELMNATDP1POLBHIF1A
SCHEMBL16613261 0.81 MCL1 (0.40) MCL1KDM4ENPC1METAP1LRRK2
SCHEMBL16613769 0.81 MCL1 (0.43) MCL1KDM4ENPC1METAP1LRRK2
SCHEMBL21213120 0.79 MCL1 (0.44) MCL1KDM4ENPC1METAP1LRRK2
SCHEMBL16613283 0.78 ALDH1A1 (0.46) KDM4ELMNATDP1POLBALDH1A1
SCHEMBL16613381 0.78 MCL1 (0.40) MCL1KDM4ENPC1METAP1NPY5R
SCHEMBL16613277 0.77 TUBB4A (0.36) KDM4ETDP1TP53SMN1; SMN2ALDH1A1
SCHEMBL16613739 0.77 ADORA1 (0.55) MCL1KDM4ENPC1METAP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed