SCHEMBL1712596

SCHEMBL1712596

CCCCCCCCCCCC(CCCCCCCC)C(CCCCCCCCCC)C(=O)OC(=O)CCC(N)C(=O)OC(=O)C(CCCCCCCCCC)C(CCCCCCCC)CCCCCCCCCCC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.37
GRIK2 Q13002 2/20 0.37
NOD1 Q9Y239 5/20 0.37
NAAA Q02083 1/20 0.36
DGKA P23743 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 3/20 0.34
LAP3 P28838 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33770 0.85 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL9981031 0.84 GRIK1 (0.46) GRIK1GRIK2NOD1NAAADGKA
SCHEMBL29200770 0.82 DGKA (0.47) DGKAMAPTLMNAALDH1A1
SCHEMBL2482147 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL15648440 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL336490 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL192213 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL336371 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL346381 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1
SCHEMBL318615 0.82 DGKA (0.50) DGKAMAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8894981-B2 Water base slurry composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 US claimed
EP-2755628-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF U.S. Cosmetics Corporation (US) 2014-07-23 EP claimed
EP-2727577-A1 Colour pigment powder, pigment dispersion and method of manufacture U.S. Cosmetics Corporation (US) 2014-05-07 EP claimed
WO-2013039483-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF US COSMETICS CORPORATION (US) 2013-03-21 WO claimed
US-20120107379-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. COSMETICS CORPORATION (US) 2012-05-03 US claimed
US-20110318286-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF US COSMETICS CORPORATION (US) 2011-12-29 US claimed
EP-2344109-A2 WATER BASED SLURRY COMPOSITION CONTAINING SURFACE-TREATED COMPOSITE PARTICLES FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. Cosmetics Corporation (US) 2011-07-20 EP claimed
EP-2148644-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE U.S. Cosmetics Corporation (US) 2010-02-03 EP claimed
US-20090191139-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. COSMETICS CORPORATION (US) 2009-07-30 US claimed
WO-2009067516-A2 WATER BASED SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE US COSMETICS CORPORATION (US) 2009-05-28 WO claimed
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE US COSMETICS CORPORATION (US) 2008-12-04 US claimed
WO-2008137175-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE US COSMETICS CORPORATION (US) 2008-11-13 WO claimed
US-8894980-B2 Wet cake composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 US disclosed
US-8894981-B2 Water base slurry composition for cosmetic products and methods of use U.S. COSMETICS CORPORATION (US) 2014-11-25 US disclosed
EP-2755628-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF U.S. Cosmetics Corporation (US) 2014-07-23 EP disclosed
EP-2727577-A1 Colour pigment powder, pigment dispersion and method of manufacture U.S. Cosmetics Corporation (US) 2014-05-07 EP disclosed
US-20090191139-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE U.S. COSMETICS CORPORATION (US) 2009-07-30 US disclosed
WO-2009067516-A2 WATER BASED SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE US COSMETICS CORPORATION (US) 2009-05-28 WO disclosed
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE US COSMETICS CORPORATION (US) 2008-12-04 US disclosed
WO-2008137175-A2 COLOUR PIGMENT POWDER, PIGMENT DISPERSION AND METHOD OF MANUFACTURE US COSMETICS CORPORATION (US) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107379-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE DSG1, CUTA, AQP3 GRIK1 3050/4885GRIK2 3620/4885NOD1 4524/4885
US-20090191139-A1 WATER BASE SLURRY COMPOSITION FOR COSMETIC PRODUCTS AND METHODS OF USE DSG1, CUTA, AQP3 GRIK1 3050/4885GRIK2 3620/4885NOD1 4524/4885
US-20110318286-A1 SPF ENHANCED EXTENDED COLOR BULK POWDERS AND METHODS OF MAKING THEREOF SDHB, SDHA, SF3B3 GRIK1 4850/4885GRIK2 4870/4885NOD1 4077/4885
US-20080299158-A1 FULLY EXTENDED COLOR BULK POWDER, BULK DISPERSION AND METHOD OF USE TYR, CUTA, PDE6D GRIK1 4871/4885GRIK2 4874/4885NOD1 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.