SCHEMBL19082889

SCHEMBL19082889

CCCCCc1cc(F)c(OCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.46
RARA P10276 2/20 0.46
RARG P13631 1/20 0.46
FFAR4 Q5NUL3 1/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
PTGS2 P35354 3/20 0.37
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 1/20 0.37
MTOR P42345 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 1/20 0.36
STAT3 P40763 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ESR1 P03372 2/20 0.36
ADRA2A P08913 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19082884 0.96 RARB (0.41) RARBRARARARGFFAR4NPC1
SCHEMBL19082868 0.95 RARB (0.49) RARBRARARARGHSD17B10TSHR
SCHEMBL19082821 0.95 RARB (0.49) RARBRARARARGHSD17B10TSHR
SCHEMBL19082928 0.92 RARB (0.47) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082924 0.92 RARB (0.45) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082856 0.91 RARB (0.44) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082867 0.91 RARB (0.44) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082888 0.91 FFAR4 (0.40) RARBRARARARGFFAR4HSD17B10
SCHEMBL19082923 0.88 RARB (0.40) RARBRARARARGFFAR4NPC1
SCHEMBL19082929 0.88 RARB (0.43) RARBRARARARGFFAR4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9994772-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-06-12 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed