Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712857 | 0.82 | GRM1 (0.42) | ALDH1A1NPC1MAPTRAB9AHSD17B10 | |
| SCHEMBL20550642 | 0.78 | LMNA (0.35) | LMNAMAPK1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8309818 | 0.75 | LMNA (0.39) | LMNAMAPK1SMN1; SMN2NPC1MAPT | |
| SCHEMBL21712867 | 0.74 | TSHR (0.31) | LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21712865 | 0.73 | GRM1 (0.31) | LMNAMAPK1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL9303456 | 0.71 | ADORA3 (0.35) | LMNAMAPK1SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL29176411 | 0.66 | CTSD (0.54) | LMNAMAPK1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL17238223 | 0.66 | TSHR (0.53) | ALDH1A1MAPTALOX15HSD17B10HTT | |
| SCHEMBL29742701 | 0.66 | TSHR (0.45) | MAPK1ALDH1A1ALOX15HSD17B10L3MBTL1 | |
| SCHEMBL8310429 | 0.64 | LMNA (0.42) | LMNAMAPK1SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183193-A1 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2023-06-15 | — | — | US | disclosed |
| CN-110603250-B | Herbicidal 4-difluoromethylbenzamides | 拜耳作物科学股份公司 | 2022-09-30 | — | — | CN | disclosed |
| EP-3619201-B1 | HERBICIDALLY ACTIVE 4-DIFLUORMETHYLBENZOYLAMIDE | BAYER CROPSCIENCE AG (DE) | 2022-08-10 | — | — | EP | disclosed |
| EP-3619201-A1 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION | Bayer CropScience Aktiengesellschaft (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-20200055829-A1 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-20 | — | — | US | disclosed |
| CN-110603250-A | Herbicidal 4-difluoromethylbenzamides | 拜耳作物科学股份公司 | 2019-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055829-A1 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION | DDT, CYP4X1, CBR3 | LMNA 3760/4885MAPK1 3774/4885SMN1; SMN2 3806/4885 |
| US-20230183193-A1 | 4-DIFLUOROMETHYL BENZOYL AMIDES WITH HERBICIDAL ACTION | DDT, CYP4X1, CBR3 | LMNA 3760/4885MAPK1 3774/4885SMN1; SMN2 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.