Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.79 |
| ▸ | THRB | P10828 | 6/20 | 0.79 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959119 | 0.89 | RORC (0.63) | RORCTHRBCDK9ALDH1A1L3MBTL1 | |
| SCHEMBL22959110 | 0.88 | RORC (1.00) | RORCTHRBCDK9CHEK1 | |
| SCHEMBL22959272 | 0.88 | RORC (0.75) | RORCTHRBCDK9CHEK1ALDH1A1 | |
| SCHEMBL22959321 | 0.87 | RORC (0.73) | RORCTHRBCDK9CHEK1ALDH1A1 | |
| SCHEMBL22959177 | 0.85 | RORC (0.80) | RORCTHRBALDH1A1THRAL3MBTL1 | |
| SCHEMBL22959179 | 0.82 | RORC (0.85) | RORCTHRBTHRA | |
| SCHEMBL22959350 | 0.80 | RORC (0.82) | RORCTHRBTHRA | |
| SCHEMBL22959412 | 0.80 | RORC (0.81) | RORCTHRBTHRA | |
| SCHEMBL22959408 | 0.79 | RORC (1.00) | RORCTHRBCDK9CHEK1THRA | |
| SCHEMBL22959117 | 0.79 | RORC (0.62) | RORCTHRBCDK9ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |