Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569599 | 1.00 | NPSR1 (0.60) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL11570524 | 1.00 | NPSR1 (0.60) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2412758 | 0.98 | SMN1; SMN2 (0.59) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2416229 | 0.93 | SMN1; SMN2 (0.54) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL2417389 | 0.89 | SMN1; SMN2 (0.46) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL16922982 | 0.89 | SMN1; SMN2 (0.46) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL3075216 | 0.86 | EPHX1 (0.68) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL9381361 | 0.83 | ALDH1A1 (0.55) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL20053080 | 0.82 | KMT2A (0.54) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL14890449 | 0.81 | EPHX2 (0.56) | NPSR1EPHX1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2020-02-25 | — | — | US | disclosed |
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2020-02-25 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | THE UNIVERSITY OF MANCHESTER (GB) | 2018-08-02 | — | — | US | disclosed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| EP-2549991-B1 | FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA | VIFOR (INTERNATIONAL) AG (CH) | 2017-11-22 | — | — | EP | disclosed |
| EP-2549991-B1 | FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA | VIFOR (INTERNATIONAL) AG (CH) | 2017-11-22 | — | — | EP | disclosed |
| US-4343942-A | BACTERICIDES | RESEARCH CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |
| US-4264494-A | Chromium complex dyestuffs for natural polyamides and synthetic nylons | BASF AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| US-4228071-A | Triazine containing fiber-reactive disazo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-10-14 | — | — | US | disclosed |
| US-4212801-A | Unsymmetrical 1:2-chromium complexes containing an azo and an azomethine bond | BASF AKTIENGESELLSCHAFT (DE) | 1980-07-15 | — | — | US | disclosed |
| US-4190726-A | Polycyclic dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| US-4170465-A | PRE- AND POST- EMERGENCE HERBICIDES | ROUSSEL UCLAF (FR) | 1979-10-09 | — | — | US | disclosed |
| US-4052374-A | UNSYMMETRICAL 1:2-CHROMIUM COMPLEXES CONTAINING AN AZO COMPOUND AND AN AZOMETHINE COMPOUND | BASF AKTIENGESELLSCHAFT (DT) | 1977-10-04 | — | — | US | disclosed |
| US-4013684-A | PREPARATION OF 2,5-DIMETHYLFURAN-3-CARBOXYLIC AMIDES | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-4001232-A | N-SUBSTITUTED PROPYLENE DIAMINE, ACETOACETIC ACID, ESTER, OR AMIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3993637-A | Chelatable triazolylazo-N-alkyl(cycloalkyl)acylacetamide dyes | EASTMAN KODAK COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570157-B2 | Cyclic diarylboron derivatives as NLRP3 inflammasome inhibitors | NLRP3, IL1B, NOD1 | NPSR1 3874/4885EPHX1 1164/4885HPGD 825/4885 |
| US-20180215772-A1 | CYCLIC DIARYLBORON DERIVATIVES AS NLRP3 INFLAMMASOME INHIBITORS | NLRP3, IL1B, NOD1 | NPSR1 3874/4885EPHX1 1164/4885HPGD 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.