⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844738 | 0.70 | MAPT (0.31) | — | |
| SCHEMBL17398541 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL25304303 | 0.68 | DAO (0.33) | — | |
| SCHEMBL22275632 | 0.67 | — | — | |
| SCHEMBL15349216 | 0.66 | MAPT (0.30) | — | |
| SCHEMBL24347990 | 0.66 | MAPT (0.33) | — | |
| SCHEMBL17398641 | 0.66 | MAPT (0.30) | — | |
| SCHEMBL20742459 | 0.65 | BACE1 (0.33) | — | |
| SCHEMBL860252 | 0.65 | — | — | |
| SCHEMBL19019963 | 0.65 | NR1D1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137297-A2 | 5,6-DIHYDRO-4H-THIENO[2,3-C]PYRROLE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023137297-A2 | 5,6-DIHYDRO-4H-THIENO[2,3-C]PYRROLE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-07-20 | — | — | WO | disclosed |