Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | GAA | P10253 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30488545 | 1.00 | TNK2 (0.41) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL30488495 | 1.00 | TNK2 (0.41) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL25862365 | 1.00 | TNK2 (0.41) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL29030601 | 1.00 | TNK2 (0.41) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL25296656 | 0.84 | CACNA2D1 (0.42) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL25256876 | 0.84 | CACNA2D1 (0.42) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL25862420 | 0.84 | CACNA2D1 (0.42) | ALDH1A1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL29326412 | 0.83 | NLRP3 (0.48) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL25300770 | 0.81 | NLRP3 (0.46) | TNK2ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL30488484 | 0.81 | NLRP3 (0.46) | TNK2ALDH1A1GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |