Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK1 | P23458 | 2/20 | 0.44 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581880 | 0.83 | HSD17B10 (0.53) | SMN1; SMN2CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL2883397 | 0.83 | HSD17B10 (0.53) | SMN1; SMN2CYP2C19HSD17B10MEN1KMT2A | |
| SCHEMBL13660831 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19LCK | |
| SCHEMBL21193767 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL3272711 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19LCK | |
| SCHEMBL1320424 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19LCK | |
| SCHEMBL3277927 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19LCK | |
| SCHEMBL29278484 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19HSD17B10 | |
| SCHEMBL30026935 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19HSD17B10 | |
| SCHEMBL29641143 | 0.82 | L3MBTL1 (0.55) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | SMN1; SMN2 2206/4885NPC1 250/4885RAB9A 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.